Estrogen-producing steroidogenic pathways in parietal cells of the rat gastric mucosa

Life Sciences

Volumn 74, Issue 18, 2004, Pages 2327-2337

  Ueyama, Takashi ^a   Shirasawa, Nobuyuki ^a   Ito, Takao ^a   Tsuruo, Yoshihiro ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Gastric mucosa; Parietal cells; Portal vein; Rat; Steroidogenic enzymes; Stomach

Indexed keywords

3ALPHA HYDROXYSTEROID DEHYDROGENASE; AROMATASE; CYTOCHROME P450; ESTRADIOL; ESTROGEN; ESTRONE; MESSENGER RNA; STEROID 17ALPHA MONOOXYGENASE; STEROID 5ALPHA REDUCTASE; TESTOSTERONE 17BETA DEHYDROGENASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; ESTRONE BLOOD LEVEL; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MESENTERIC ARTERY; METABOLITE; NONHUMAN; PORTAL VEIN; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROID METABOLISM; STEROIDOGENESIS; STOMACH MUCOSA; STOMACH PARIETAL CELL; TESTOSTERONE BLOOD LEVEL;

EID: 1342324044     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.10.005     Document Type: Article

References (32)

1. Adamski J., Jakob F.J. A guide to 17β-hydroxysteroid dehydrogenases. Molecular and Cellular Endocrinology. 171(1-2):2001;1-4.
2. Akinola L.A., Poutanen M., Vihko R. Cloning of rat 17β- hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes. Endocrinology. 137(5):1996;1572-1579.
3. Andersson S., Bishop R.W., Russell D.W. Expression cloning and regulation of steroid 5α-reductase, an enzyme essential for male sexual differentiation. Journal of Biological Chemistry. 264(27):1989;16249-16255.
4. Biswas M.G., Russell D.W. Expression cloning and characterization of oxidative 17β- and 3α-hydroxysteroid dehydrogenases from rat and human prostate. Journal of Biological Chemistry. 272(25):1997;15959-15966.
5. Deyashiki Y., Ohshima K., Nakanishi M., Sato K., Matsuura K., Hara A. Molecular cloning and characterization of mouse estradiol 17β- dehydrogenase (A-specific), a member of the aldoketoreductase family. Journal of Biological Chemistry. 270(18):1995;10461-10467.
6. Farrell G.C., Koltai A., Murray M. Source of raised serum estrogens in male rats with portal bypass. Journal of Clinical Investigation. 81(1):1988;221-228.
7. Farthing M.J., Vinson G.P., Edwards C.R., Dawson A.M. Testosterone metabolism by the rat gastrointestinal tract, in vitro and in vivo. Gut. 23(3):1982;226-234.
8. Geissler W.M., Davis D.L., Wu L., Bradshaw K.D., Patel S., Mendonca B.B., Elliston K.O., Wilson J.D., Russell D.W., Andersson S. Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3. Nature Genetics. 7(1):1994;34-39.
9. Ghersevich S., Nokelainen P., Poutanen M., Orava M., Autio-Harmainen H., Rajaniemi H., Vihko R. Rat 17β-hydroxysteroid dehydrogenase type 1: primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo. Endocrinology. 135(4):1994;1477-1487.
10. Hickey G.J., Krasnow J.S., Beattie W.G., Richard J.S. Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3′, 5′-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5′ genomic DNA. Molecular Endocrinology. 4(1):1990;3-12.
11. Imai M., Shimada H., Okada Y., Matsushima-Hibiya Y., Ogishima T., Ishimura Y. Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P-450 in rat adrenal cortex. FEBS Letter. 263(2):1990;299-302.
12. Kitawaki J., Yoshida N., Osawa Y. An enzyme-linked immunosorbent assay for quantitation of aromatase cytochrome P-450. Endocrinology. 124(3):1989;1417-1423.
13. Le Goascogne C., Sananès N., Eychenne B., Gouézou M., Baulieu E.E., Robel P. Androgen biosynthesis in the stomach: expression of cytochrome P450 17α-hydroxylase/17,20-lyase messenger ribonucleic acid and protein, and metabolism of pregnenolone and progesterone by parietal cells of the rat gastric mucosa. Endocrinology. 136(4):1995;1744-1752.
14. Makino T. Radioimmunoassay of sex steroids. Folia Endocrinologica Japonica (in Japanese). 49(3):1973;629-645.
15. Mellon S.H., Bair S.R., Monis H. P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities. Journal of Biological Chemistry. 270(4):1995;1643-1649.
16. Namiki M., Kitamura M., Buczko E., Dufau M.L. Rat testis P-450 17α cDNA: the deduced amino acid sequence, expression and secondary structural configuration. Biochemical Biophysical Research Communications. 157(2):1988;705-712.
17. Nokelainen P., Peltoketo H., Vihko R., Vihko P. Expression cloning of a novel estrogenic mouse 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat. Molecular Endocrinology. 12(7):1998;1048-1059.
18. Nudel U., Zakut R., Shani M., Neuman S., Levy Z., Yaffe D. The nucleotide sequence of the rat cytoplasmic β-actin gene. Nucleic Acids Research. 11(6):1983;1759-1771.
19. Oonk R.B., Krasnow J.S., Beattie W.G., Richards J.S. Cyclic AMP-dependent and -independent regulation of cholesterol side chain cleavage cytochrome P-450 (P-450scc) in rat ovarian granulosa cells and corpora lutea. cDNA and deduced amino acid sequence of rat P-450scc. Journal of Biological Chemistry. 264(36):1989;21934-21942.
20. Osawa Y., Yoshida N., Fronckowiak M., Kitawaki J. Immunoaffinity purification of aromatase cytochrome P-450 from human placental microsomes, metabolic switching from aromatization to 1β and 2β-monohydroxylation, and recognition of aromatase isozymes. Steroids. 50(1-3):1987;11-28.
21. Peltoketo H., Luu-The V., Simard J., Adamski J. 17β-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes. Journal of Molecular Endocrinology. 23(1):1999;1-11.
22. Penning T.M. Molecular endocrinology of hydroxysteroid dehydrogenases. Endocrine Reviews. 18(3):1997;281-305.
23. Simpson E.R., Mahendroo M.S., Means G.D., Kilgore M.W., Hinshelwood M.M., Graham-Lorence S., Amarneh B., Ito Y., Fisher C.R., Michael M.D., Mendelson C.R. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocrine Reviews. 15(3):1994;342-355.
24. Stauber R.E., Rosenblum E., Eagon P.K., Gavaler J.S., Van Thiel D.H. The effect of portal-systemic shunting on hepatic sex hormone receptors in male rats. Gastroenterology. 100(1):1991;168-174.
25. Stolz A., Rahimi-Kiani M., Ameis D., Chan E., Ronk M., Shively J.E. Molecular structure of rat hepatic 3α-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family. Journal of Biological Chemistry. 266(23):1991;15253-15257.
26. Su J., Lin M., Napoli J.L. Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17β/3α-hydroxysteroid/ retinoid short chain dehydrogenase/reductase. Endocrinology. 140(11):1999;5275-5284.
27. Tsuruo Y., Ishimura K., Fujita H., Osawa Y. Immunocytochemical localization of aromatase-containing neurons in the rat brain during pre- and postnatal development. Cell and Tissue Research. 278(1):1994;29-39.
28. Tsai-Morris C.H., Khanum A., Tang P.Z., Dufau M.L. The rat 17β-hydroxysteroid dehydrogenase type III: molecular cloning and gonadotropin regulation. Endocrinology. 140(8):1999;3534-3542.
29. Ueyama T., Shirasawa N., Numazawa M., Yamada K., Shelangouski M., Ito T., Tsuruo Y. Gastric parietal cells: potent endocrine role in secreting estrogen as a possible regulator of gastro-hepatic axis. Endocrinology. 143(8):2002;3162-3170.
30. Yoshida T., Tanemori K., Inatomi K., Ozaki H., Takagi S., Makino T., Kambegawa A. Radioimmunoassay of androstenedione. Clinical Endocrinology (in Japanese). 22(5):1974;671-676.
31. 4 isomerase cDNAs and differential tissue-specific expression of the corresponding mRNAs in steroidogenic and peripheral tissues. Journal of Biological Chemistry. 266(1):1991;583-593.
32. Zhou M.Y., del Carmen Vila M., Gomez-Sanchez E.P., Gomez-Sanchez C.E. Cloning of two alternatively spliced 21-hydroxylase cDNAs from rat adrenal. Journal of Steroid Biochemistry Molecular Biology. 62(4):1997;277-286.