Attentional Modulation of Prepulse Inhibition: A New Startle Paradigm

Neuropsychobiology

Volumn 49, Issue 2, 2004, Pages 88-93

  Heekeren, Karsten ^a   Meincke, Ulrich ^a   Geyer, Mark A ^b   Gouzoulis Mayfrank, Euphrosyne ^a,c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Attention; Prepulse inhibition; Sensorimotor gating; Startle reaction

Indexed keywords

ADULT; ARTICLE; ATTENTION; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; HUMAN; MALE; NORMAL HUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; SAMPLE SIZE; SENSORIMOTOR FUNCTION; STARTLE REFLEX;

ACOUSTIC STIMULATION; ADULT; ATTENTION; HUMANS; INHIBITION (PSYCHOLOGY); MALE; REACTION TIME; REFLEX, ACOUSTIC; RELAXATION; STARTLE REACTION; TIME FACTORS;

EID: 1342312182     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076416     Document Type: Article

References (20)

1. Graham FK: Presidential Address, 1974. The more or less startling effects of weak prestimulation. Psychophysiology 1975;12:238-248.
2. Norris CM, Blumenthal TD: A relationship between inhibition of the acoustic startle response and the protection of prepulse processing. Psychobiology 1996;24:160-168.
3. Braff DL, Geyer MA: Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry 1990;47:181-188.
4. Cadenhead KS, Geyer MA, Braff DL: Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am J Psychiatry 1993;150:1862-1867.
5. Meincke U, Topper R, Hoff P: The electrically elicited startle blink reflex in patients with schizophrenia: A threshold study of different reflex components. Neuropsychobiology 1999;39:76-80.
6. Silverstein LD, Graham FK, Calloway JM: Preconditioning and excitability of the human orbicularis oculi reflex as a function of state. Electroencephalogr Clin Neurophysiol 1980;48:406-417.
7. Filion DL, Dawson ME, Schell AM: The psychological significance of human startle eyeblink modification: A review. Biol Psychol 1998;47:1-43.
8. Filion DL, Dawson ME, Schell AM: Modification of the acoustic startle-reflex eyeblink: A tool for investigating early and late attentional processes. Biol Psychol 1993;35:185-200.
9. Bradley MM, Cuthbert BN, Lang PJ: Pictures as prepulse: Attention and emotion in startle modification. Psychophysiology 1993;30:541-545.
10. Braff DL, Perry W, Cadenhead K, Swerdlow NR, Geyer MA: Attentional manipulations of prepulse inhibition of the startle reflex. Biol Psychiatry 1997;41:65S.
11. Dawson ME, Schell AM, Swerdlow NR, Filion DL: Cognitive, clinical, and neurophysiological implications of startle modification; in Lang PJ, Simons RF, Balaban M (eds): Attention and Orienting: Sensory and Motivational Processes. Hillsdale, Erlbaum, 1997, pp 257-327.
12. Braff DL, Grillon C, Geyer MA: Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 1992;49:206-215.
13. Braff DL, Geyer MA, Light GA, Sprock J, Perry W, Cadenhead KS, Swerdlow NR: Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res 2001;49:171-178.
14. Blumenthal TD: Short lead interval startle modification; in Dawson ME, Schell AM, Böhmelt AH (eds): Startle Modification: Implications for Neuroscience, Cognitive Science and Clinical Science. New York, Cambridge University Press, 1999, pp 51-71.
15. Silverstein LD, Graham FK, Bohlin G: Selective attention effects on the reflex blink. Psychophysiology 1981;18:240-247.
16. Filion DL, Dawson ME, Schell AM: Probing the orienting response with startle modification and secondary reaction time. Psychophysiology 1994;31:68-78.
17. Jennings PD, Schell AM, Filion DL, Dawson ME: Tracking early and late stages of information processing: Contributions of startle eyeblink reflex modification. Psychophysiology 1996;33:148-155.
18. Hazlett EA, Dawson ME, Schell AM, Nuechterlein KH: Attentional stages of information processing during a continuous performance test: A startle modification analysis. Psychophysiology 2001;38:669-677.
19. Wynn JK, Dawson ME, Schell AM: Discrete and continuous prepulses have differential effects on startle prepulse inhibition and skin conductance orienting. Psychophysiology 2000;37:224-230.
20. Hackley SA, Graham FK: Early selective attention effects on cutaneous and acoustic blink reflexes. Physiol Psychol 1984;11:235-242.