Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity

Molecular Pharmacology

Volumn 65, Issue 3, 2004, Pages 655-664

  Burcham, Philip C ^a   Fontaine, Frank R ^a   Kaminskas, Lisa M ^a   Petersen, Dennis R ^b   Pyke, Simon M ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALDEHYDE; ALLYL ALCOHOL; AMINOGUANIDINE; BOVINE SERUM ALBUMIN; CARBONYL DERIVATIVE; CARNOSINE; DIHYDRALAZINE; HYDRALAZINE; HYDRAZONE DERIVATIVE; LYSINE; METHOXYAMINE; PEPTIDE; PYRIDOXAMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DNA INTERACTION; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG TARGETING; IMMUNOREACTIVITY; LIVER CELL; MALE; MASS SPECTROMETRY; MICHAEL ADDITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; WESTERN BLOTTING;

ACROLEIN; ANIMALS; ANTIHYPERTENSIVE AGENTS; CELLS, CULTURED; CYTOPROTECTION; DRUG TOXICITY; HEPATOCYTES; HYDRALAZINE; MICE; PROTECTIVE AGENTS; PROTEINS;

EID: 1342308332     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.3.655     Document Type: Article

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