Cardiac heart disease in the era of sucrose polyester, Helicobacter pylori and Chlamydia pneumoniae

Medical Hypotheses

Volumn 62, Issue 2, 2004, Pages 257-267

  Fouad, F M ^a   Mamer, Orval ^a   Sauriol, Francois ^a   Khayyal, M ^a   Lesimple, A ^a   Ruhenstroth Bauer, G ^b  

^a MCGILL UNIVERSITY   (Canada)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARABINITOL; CHOLESTEROL; ESSENTIAL FATTY ACID; LAURIC ACID; LIPID; MANNITOL; PALMITIC ACID; PANCREAS ENZYME; SORBITOL; SUCROSE POLYESTER; TRIACYLGLYCEROL; VITAMIN;

ABSORPTION; BACTERIAL INFECTION; CARDIOVASCULAR DISEASE; CELL ACTIVATION; CELL MEMBRANE; CHLAMYDOPHILA PNEUMONIAE; ENDOTHELIUM CELL; ERYTHROCYTE FRAGILITY; FAT INTAKE; GASTRITIS; GROWTH DISORDER; HEART DISEASE; HELICOBACTER PYLORI; HUMAN; INFERTILITY; INFLAMMATION; ISCHEMIC HEART DISEASE; LIPID ABSORPTION; LIPID METABOLISM; LIPOLYSIS; MICELLE; NONHUMAN; OXIDATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REVIEW; SEROLOGY; SKIN DEFECT;

CHLAMYDIA; CHLAMYDOPHILA PNEUMONIAE; HELICOBACTER; HELICOBACTER PYLORI; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 1342289614     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(03)00301-3     Document Type: Article

References (95)

1. Woodward M, Morrison C, McColl K. An investigation into factors associated with Helicobacter pylori infection. J Clin Epidemiol 2000;53:175-81; Leong RW-L, Sung JJY. Review article: helicobacter species and hepatobiliary diseases. Aliment Pharmacol Ther 2002;16:1037-45.
2. Woodward M, Morrison C, McColl K. An investigation into factors associated with Helicobacter pylori infection. J Clin Epidemiol 2000;53:175-81; Leong RW-L, Sung JJY. Review article: helicobacter species and hepatobiliary diseases. Aliment Pharmacol Ther 2002;16:1037-45.
3. Patel P, Carrington D, Strachan DP, et al. Fibrinogen: a link between chronic infection and coronary heart disease. Lancet 1994;343:1634-5.
4. Martin-de-Argila C, Boixeda D, Canton R, Gisber JP, Fuertes A. High seroprevalence of Helicobacter pylori infection in coronary heart disease. Lancet 1995;346:310.
5. Law MR, Morris JK. Why is mortality higher in poorer area and in more northern areas of England and Wales? J Epidemiol Community Health 1998;52:344-52.
6. Caselli M, Zaffoni E, Ruina M, et al. Helicobacter pylori and chronic bronchitis. Scand J Gastroenterol 1999;34:828-30.
7. Haan M, Kaplan GA, Camacho T. Poverty and health: prospective evidence from the Alameda County study. Am J Epidemiol 1987;125:989-98.
8. Eames M, Ben-Sholomo Y, Marmot MG. Social deprivation and premature mortality: regional comparison across England. BMJ 1993;307:1097-102.
9. Marmot MG, Shipley MJ. Do socioeconomic differences in mortality persist after retirement? 25 Year follow up of civil servants from the first Whitehall study. BMJ 1996;313:1177-80.
10. Dhurandhar NV. Infectobesity: obesity of infectious origin. J Nutr 2001;131:2794S-7S.
11. Mattson FH, Volpenhein RA. The digestion and adsorption of triglycerides. J Biol Chem 1964;239:2772-7.
12. Surpuriya V, Higuchi WI. Two-step interfacial barrier mechanism for the transport of micelles-solubilized solute across an oil-water interface. Biochem Biophys Acta 1972;290:375-83.
13. Jandacek RJ. The effect of nonabsorbable lipids on the intestinal absorption of lipophiles. Drug Metab Rev 1982;13:695-714.
14. Rizzi GP, Taylor HM. A solvent free synthesis of sucrose polyester. J Am Oil Chem Soc 1978;55:398-401.
15. Cooper DA, Berry DA, Spendel VA, et al. Olestra dose response on fat-soluble and water-soluble nutrients in the pig. J Nutr 1997;127:1573S-88S.
16. Cooper DA, Berry DA, Spendel VA, et al. Nutritional status of pigs fed olestra with and without increased dietary levels of vitamins A and E in long term studies. J Nutr 1997;127:1609S-35S.
17. Cooper DA, Berry DA, Spendel VA, et al. The domestic pig as a model for evaluating olestra's nutritional effects. J Nutr 1997;127:1555S-65S.
18. Schlagheck TG, Riccardi KA, Zorich NL, et al. Olestra dose response on fat-soluble and water-soluble nutrients in humans. J Nutr 1997;127:1646S-65S.
19. Schlagheck TG, Kesler JM, Jones MB, et al. Olestra effect on vitamins D and E in humans can be offset by increasing dietary levels of these vitamins. J Nutr 1997;127:1666S-85S; Webb DR, Harrison GG, Lee M-J, Haung M-H. Estimated consumption and eating frequency of olestra from savory snacks using menu census data. J Nutr 1997;127:1547S-54S.
20. Schlagheck TG, Kesler JM, Jones MB, et al. Olestra effect on vitamins D and E in humans can be offset by increasing dietary levels of these vitamins. J Nutr 1997;127:1666S-85S; Webb DR, Harrison GG, Lee M-J, Haung M-H. Estimated consumption and eating frequency of olestra from savory snacks using menu census data. J Nutr 1997;127:1547S-54S.
21. Glueck CJ, Jandacek RJ, Ravi Subbiah MT, et al. Effect of sucrose polyester on fecal bile acid excretion and composition in man. Am J Clin Nutr 1980;33:2177-81.
22. Miller KW, Lawson KD, Tallmadge DH, et al. Disposition of ingested olestra in the Fischer 344 rat. Appl Toxicol 1995;24:229-37.
23. Fallat RW, Glueck CJ, Lutmer R, Mattson FH. Short term study of sucrose polyester, a nonabsorbable fat-like material as a dietary agent for lowering plasma cholesterol. Am J Clin Nutr 1976;29:1204-15.
24. Mattson FH, Volpenhein RA. Hydrolysis of fully esterified alcohols containing from one to eight hydroxyl groups by the lioplytic enzymes of rat pancreatic juice. J Lipid Res 1972;13:325-8.
25. Mattson FH, Nolen GA. Absorbability by rats of compounds containing from one to eight ester groups. J Nutr 1972;102:1171-5.
26. Bernhardt CA. Olestra - a non-caloric fat replacement. Food Technol Int - Europe 1988:176-8.
27. Kester JJ. Food product development using olestra as a fat substitute. In: Yalpani M, editor. Science for the food industry for the 21st century Biotechnology, supercritical fluids, membranes and other advanced techniques for low calorie, healthy food alternatives. Mount Prospect, IL: ATL Press; 1993. p. 37-50.
28. Glueck CJ, Mattson FH, Jandacek RJ. The lowering of plasma cholesterol by sucrose polyester in subjects consuming diets with 800, 300 or less than 50 mg of cholesterol per day. Am J Chem Nutr 1979;32:1636-44.
29. Roberts RJ, Leff RD. Influence of absorbable and nonabsorbable lipids and lipidlike substances on drug bioavailability. Clin Pharmacol Theor 1989;43:299-304.
30. Sletten EG, Hollander D, Dadufalza V. Does the nonabsorbable fat (sucrose polyester) interfere with the Intestinal absorption of vitamin A? Acta Vitaminol Enzymol 1985;7:49-53.
31. Fouad FM, Mamer OA, Shahidi F. Biogenesis of hepatic-acute phase response to trauma. Med Hypotheses 1996;47:157-77.
32. Fouad FM, Mamer OA, Sauriol F, Shahidi F. Chemical and epidemiological aspects of modified butter oil fraction. J Toxicol Environ Health 1998;1:149-79.
33. Fouad FM, Marshall WD, Farrell PG, Prehm P. Immunoelectrophoretic pattern of native mucosal intracellular glycoproteins of hog healthy and drug-intoxicated stomachs and of hog body fluids. J Toxicol Environ Health 1993;39:355-74.
34. Fouad FM, Waldron-Edward D. Isolation and characterization of human and canine gastric mucosal glycoproteins and their degradation by proteases and acid-hydrolases. Hoppe-Seyler's Z Physiol Chem 1980;361:703-13.
35. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999;340:115-26.
36. Barath P, Fishbein MC, Cao J, et al. Detection and localization of tumor necrosis factor in human atheroma. Am J Cardiol 1999;65:297-303.
37. Rus HG, Niculescu F, Vlaicu R. Tumor necrosis factor-alpha in human arterial wall with atherosclerosis. Atherosclerosis 1991;89:247-54.
38. Pober JS, Cotran RS. Cytokines and endothelial cell biology. Physiol Rev 1990;70:427-51.
39. McCarty MF. Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes and visceral obesity: down-regulation with essential fatty acids, ethanol and pentoxifylline. Med Hypotheses 1997;52:465-77.
40. Schumacher A, Arnesen H, Seljeflot I, Sommervoil L. Increased levels of soluble markers of endothelial dysfunction in patients with atherosclerosis heart diseases. Scand J Clin Invest 2002;62:59-68.
41. Schumacher A, Seljeflot I, Lerkerod AB, et al. Positive Chlamydia pneumoniae serology is associated with elevated tumor necrosis factor alpha in patients with coronary heart disease. Atherosclerosis 2002;164:153-60.
42. Fouad FM, Goldberg M, Ruhenstroth-Bauer G. Plasma protein determination as a clinical probe for liver injury in rats induced by thioacetamide, alloxan or ixoten. J Clin Chem Clin Biochem 1983;21:203-8.
43. Fouad FM, Farrell PG, Marshall WD, Scherer R, Ruhenstroth-Bauer G. Partially hepatectomized rats: a model for the study of the effect of toxins on the plasma protein profile of nascent hepatocytes. J Toxicol Environ Health 1992;36:43-57.
44. Fouad FM, Marshall WD, Farrell PG, FitzGerlad S. Acute phase plasma protein response to cholera intoxication in healthy and diabetic rats. J Toxicol Environ Health 1993;38:1-18.
45. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
46. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
47. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
48. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
49. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
50. Delanghe JR, Langlois MR, De Bacquer D, et al. Discriminative value of serum amyloid A and other acute-phase proteins for coronary heart disease. Atherosclerosis 2002;160:471-6; Lamarque D, Moran AP, Szepes Z, Delchier JC, Whittle BJ. Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase. Br J Pharmacol 2000;130:1531-8; Beil W, Enss ML, Muller S, et al. Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells. J Clin Microbiol 2000;38:2215-8; Alkout AM, Blackwell CC, Weir DM. Increased inflammatory responses of persons of blood group O to Helicobacter pylori. Infect Dis 2000;181:1364-9; Fiocca R, Necchi V, Sommi P, et al. Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium. J Pathol 1999;188:220-6; Reyrat JM, Lanzavecchia S, Lupetti P, et al. 3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin. J Mol Biol 1999;290:459-70.
51. Streblow DN, Orloff S, Nelson JA. Do pathogens accelerate atherosclerosis? J Nutr 2001;131:2798S-804S.
52. Shor A, Kuo CC, Patton DL. Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatus plaques. S Afr Med J 1992;82:158-61.
53. Ku CC, Shor A, Campbell LA, et al. Demonstration of Chlamydia pneumoniae in atherosclerosis lesions of coronary arteries. J Infect Dis 1993;167:845-9.
54. Gallin JI, Kaye D, O'Leary WM. Serum lipids in infection. N Engl J Med 1969;281:1081-6.
55. Alvarez C, Ramos A. Lipids, lipoproteins and apoproteins in serum during infection. Clin Chem 1986;32:142-5.
56. Kerttula Y, Weber T. Serum lipids in pneumonia of different aetiology. Ann Clin Res 1988;20:184-8.
57. Niemela S, Karttunen T, Korhonen T, Laara, et al. Could Helicobacter pylori infection increase the risk of coronary hear disease by modifying serum lipid concentrations? Heart 1995;75:573-5.
58. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Accociation of Helicobacter pylori infection with elevated serum lipids. Atherosclerosis 1999;142:207-10.
59. Laurila A, Bloigu A, Nayha S, Hassi J, Leinonen M, Saikku P. Chlamydia pneumoniae antibodies and serum lipids in Finish men. Br Med J 1997;314:1456-7.
60. Grunfeld C, Gulli R, Moser AH, Gavin LA, Feingold KR. Effect of tumor necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat. J Lipid Res 1989;30:579-85.
61. Regnstrom J, Jovinge S, Bavenholm P, et al. Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degree of coronary artery disease. J Intern Med 1998;243:109-13.
62. Strachan DP, Mendall MA, Carrrington D, et al. Helicobacter pylori infection to 13-year mortality and incident ischemic heart disease in the caerphilly. Prospect Heart Dis Study Circulation 1998;98:1286-90.
63. Ma JL, You WC, Gail MH, et al. Helicobacter pylori infection and mode of transmission in a population at high risk of stomach cancer. Intl J Epidemiol 1998;27:570-3.
64. The Atherosclerosis Risk in Communities (ARIC) Study Investigators Folsom AR, Nieto FJ, Sorlie P, Chambless LE, Graham DY. Helicobacter pylori serpositivity and coronary heart disease incidence. Circulation 1998;98:845-50.
65. Campbell TC, Parpia B, Chen J. Diet, life style and the etiology of coronary heart disease: The Cornell China Study. Am J Cardiol 1998;82:18T-21T.
66. Baschetti R. Letter to the Editor. Atherosclerosis 1999;147:190.
67. Danesh J, Wong Y, Ward M, Muir J. Chronic infection with Helicobacter pylori, Chlamydia pneumoniae, or cytomegalovirus: population based study of coronary heart disease. Heart 1999;81:245-7.
68. Wald NJ, Law MR, Morris JK, Bagnall AM. Helicobacter pylori infection and mortality from ischaemic heart disease: negative result from a large, prospective study. BMJ 1997;315:1199-201.
69. Cook D, Mendall MA, Whincup PA, et al. C-reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors. Atherosclerosis 2000;149:139-50.
70. Levine J, Gussow JD, Hastings D, Eccher A. Author's financial relationships with the food and beverage industry and their published positions on the fat substitute olestra. Am J Public Health 2003;93:664-9.
71. What is new - CSPI Press Release, December 3, 1997. Available from: http:/cspinet.org/news/amaoles.htm.
72. Klontz KC. Measurement of selected fecal parameters in subjects consuming increasing levels of olestra (FAP 3997, vol. 289). Office of Premarket Approval (HFS-216), December 26; 1995.
73. Melman A, Christ GJ. The hemodynamics of erection and the pharmacotherapies of erectile dysfunction. Heart Dis 2002;4:252-64.
74. Pukkala E, Kulmala I, Hovi SL, et al. Causes of death among Finnish women with cosmetic breast implants 1971-2001. Ann Plast Surg 2003;51:339-42; Brinton LA, Lubin JH, Burich, et al. Mortality among augmentation mammoplasty patients. Epidemiology 2001;12:321-6.
75. Pukkala E, Kulmala I, Hovi SL, et al. Causes of death among Finnish women with cosmetic breast implants 1971-2001. Ann Plast Surg 2003;51:339-42; Brinton LA, Lubin JH, Burich, et al. Mortality among augmentation mammoplasty patients. Epidemiology 2001;12:321-6.
76. Amer VA, Kupranyez DB, Baker BE. Physical and chemical characteristics of butter fat fractions obtained by crystallization from molten fat. J Am Oil Chem Soc 1985;62:1551-7.
77. Fouad FM, van de Voort FR, Marshall WD, Farrell PG. A critical evaluation of thermal modification of butter oil. J Am Oil Chem Soc 1990;67:981-8; Fouad FM, van de Voort FR, Marshall WD, Farrell PG. Further development in thermal modification of butter oil. J Food lipids 1993;1:119-41.
78. Fouad FM, van de Voort FR, Marshall WD, Farrell PG. A critical evaluation of thermal modification of butter oil. J Am Oil Chem Soc 1990;67:981-8; Fouad FM, van de Voort FR, Marshall WD, Farrell PG. Further development in thermal modification of butter oil. J Food lipids 1993;1:119-41.
79. Fouad FM, van de Voort FR, Marshall WD, Farrell PG. Modification of butter oil: effects of super critical carbon dioxide extraction and interesterification. J Food Lipids 1994;1:195-219.
80. Allgood GS, Kuter DJ, Roll KT, Taylor SL, Zorich NL. Post marketing surveillance of new food ingredients: results from the program with fat replacer olestra. Regul Toxicol Pharmacol 2001;33:224-33.
81. Cook B, Cooper D, Fitzpatrick D, et al. The influence of high fat meal compared to an olestra meal on coronary artery endothelial dysfunction by Rubidium (Rb)-82 positron emission tomography (PET) and on post prandial serum triglycerides. Clin Positron Imaging 2000;4:150.
82. Patterson RE, Kristal AR, Peters JC, et al. Changes in diet, weight, and serum lipid levels associated with olestra consumption. Arch Inetrn Med 2000;160:2600-4.
83. McRorie J, Kesler J, Bishop L, et al. Effects of wheat barn and olestra on objective measures of stool and subjective reports of GI symptoms. Am J Gastroenterol 2000;95:1244-52.
84. McRorie J, Brown S, Cooper R, et al. Effects of dietary fiber and olestra on regional apparent viscosity and water content of digesta residues in porcine large intestine. Ailment Pharmacol Ther 2000;14:471-7.
85. Cooper DA, Curran-Celentano J, Ciulla TA, et al. Olestra consumption is not associated with macular pigment optical density in a cross sectional volunteers sample in Indianapolis. J Nutr 2000;130:642-7.
86. Balasekaran R, Porter JL, Santa Ana CA, Fordtran JS. Positive results on tests for steatorrhea in persons consuming olestra potato chips. Ann Intern Med 2000; 132:279-82.
87. Neumark-Sztanier D, Kristal AR, Thornquist MD, et al. Early adopters of olestra containing foods. Who are they? J Am Diet Assoc 2000;100:198-204.
88. Blackburn G. Reduced-fat fallacy. Health News 2000;6:4.
89. Rubin E, Rottenberg H. Ethanol-induced injury and adaptation in biological membranes. Fed Proc 1982;41:2465-71.
90. Nishimura T, Yoshida Y, Watanabe F, et al. Blood level of mitochondrial aspartate aminotransferase as an indicator of the extent of ischemic necrosis of the rat liver. Hepataology 1986;6:701-7.
91. Figge K, Haigh-Baird SD. Biodegradation of sucrose poly fatty acid esters in soils. Chemosphere 1997;34:2621-36.
92. Lee DM, Ventullo PM. Degradation of olestra, a non-caloric fat replacer, by microorganisms isolated from activated sludge and other environments. Biodegradation 1996;7:256-65.
93. Weiss J, Papke O, Bignert A, et al. Concentrations of dioxins and other organochlorines (PCBs, DDTs, HCHs) in human milk from Seveso, Milan and a Lombardian rural area in Italy: a study performed 25 years after the heavy dioxin exposure in Seveso. Acta Paediatr 2003;92:467-72.
94. National Toxicology Program, US Department of Health and Human Services, NTP-CERHR Expert panel report on the reproductive and developmental toxicity of propylene glycol, December 2002 NTP-CENTER-PG-02.
95. Chaturvedi N, Fuller JH. Risk of breast cancer is also increased among Danish female air line cabin attendants. BMJ 1996;312:253.