메뉴 건너뛰기




Volumn 188, Issue 2, 1999, Pages 220-226

Release of Helicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium

Author keywords

Gastric cells; Helicobacter pylori; Outer membrane vesicles; Secretion; Toxin internalization; Vacuolating cytotoxin

Indexed keywords

CYTOTOXIN;

EID: 0032982467     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199906)188:2<220::AID-PATH307>3.0.CO;2-C     Document Type: Article
Times cited : (223)

References (39)
  • 1
    • 0031911053 scopus 로고    scopus 로고
    • Evidence for specific secretion rather than autolysis in the release of some Helicobacter pylori proteins
    • Vanet A, Labigne A. Evidence for specific secretion rather than autolysis in the release of some Helicobacter pylori proteins. Infect Immun 1998; 66: 1023-1027.
    • (1998) Infect Immun , vol.66 , pp. 1023-1027
    • Vanet, A.1    Labigne, A.2
  • 2
    • 0030021824 scopus 로고    scopus 로고
    • Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis
    • Phadnis SH, Parlow M, Levy M, et al. Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis. Infect Immun 1996; 64: 905-912.
    • (1996) Infect Immun , vol.64 , pp. 905-912
    • Phadnis, S.H.1    Parlow, M.2    Levy, M.3
  • 3
    • 0031003615 scopus 로고    scopus 로고
    • Localization of Helicobacter pylori urease and heat shock protein in human gastric biopsies
    • Dunn BE, Vakil NB, Schneider BG, et al. Localization of Helicobacter pylori urease and heat shock protein in human gastric biopsies. Infect Immun 1997; 65: 1181-1188.
    • (1997) Infect Immun , vol.65 , pp. 1181-1188
    • Dunn, B.E.1    Vakil, N.B.2    Schneider, B.G.3
  • 4
    • 0029963677 scopus 로고    scopus 로고
    • Cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
    • Censini S, Lange C, Xiang Z, et al. Cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 1996; 93: 14 648-14 653.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14648-14653
    • Censini, S.1    Lange, C.2    Xiang, Z.3
  • 5
    • 0027450561 scopus 로고
    • The complete general secretory pathway in Gram-negative bacteria
    • Pugsley AP. The complete general secretory pathway in Gram-negative bacteria. Microbiol Rev 1993; 57: 50-108.
    • (1993) Microbiol Rev , vol.57 , pp. 50-108
    • Pugsley, A.P.1
  • 6
    • 0028308711 scopus 로고
    • Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains
    • Cover TL, Tummuru MKR, Cao P, Thompson SA, Blaser MJ. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J Biol Chem 1994; 269: 10 566-10 573.
    • (1994) J Biol Chem , vol.269 , pp. 10566-10573
    • Cover, T.L.1    Tummuru, M.K.R.2    Cao, P.3    Thompson, S.A.4    Blaser, M.J.5
  • 7
    • 0028355422 scopus 로고
    • Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease
    • Telford JL, Ghiara P, Dell'Orco M, et al. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med 1994; 179: 1653-1658.
    • (1994) J Exp Med , vol.179 , pp. 1653-1658
    • Telford, J.L.1    Ghiara, P.2    Dell'Orco, M.3
  • 8
    • 0028365481 scopus 로고
    • Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: Structural similarities with the IgA protease type of exported protein
    • Schmitt W, Haas R. Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol Microbiol 1994; 12: 307-319.
    • (1994) Mol Microbiol , vol.12 , pp. 307-319
    • Schmitt, W.1    Haas, R.2
  • 9
    • 0029898566 scopus 로고    scopus 로고
    • Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin
    • Lupetti P, Heuser JE, Manetti R, et al. Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin. J Cell Biol 1996; 133: 801-807.
    • (1996) J Cell Biol , vol.133 , pp. 801-807
    • Lupetti, P.1    Heuser, J.E.2    Manetti, R.3
  • 10
    • 0030809535 scopus 로고    scopus 로고
    • Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin reveals its pattern of assembly
    • Cover TL, Hanson PI, Heuser JE. Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin reveals its pattern of assembly. J Cell Biol 1997; 138: 759-769.
    • (1997) J Cell Biol , vol.138 , pp. 759-769
    • Cover, T.L.1    Hanson, P.I.2    Heuser, J.E.3
  • 11
    • 0029822812 scopus 로고    scopus 로고
    • Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cells
    • Garner JA, Cover TL. Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cells. Infect Immun 1996; 64: 4197-4203.
    • (1996) Infect Immun , vol.64 , pp. 4197-4203
    • Garner, J.A.1    Cover, T.L.2
  • 12
    • 0030663325 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia
    • Ricci V, Fiocca R, Romano M, Solcia E, Ventura U. Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia. J Pathol 1997; 183: 453-459.
    • (1997) J Pathol , vol.183 , pp. 453-459
    • Ricci, V.1    Fiocca, R.2    Romano, M.3    Solcia, E.4    Ventura, U.5
  • 13
    • 0015853721 scopus 로고
    • Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidis
    • Devoe IW, Gilchrist JE. Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidis. J Exp Med 1973; 138: 1156-1167.
    • (1973) J Exp Med , vol.138 , pp. 1156-1167
    • Devoe, I.W.1    Gilchrist, J.E.2
  • 14
    • 0020424303 scopus 로고
    • Generation and release of DNA-binding vesicles by Haemophilus influenzae during induction and loss of competence
    • Deich RA, Hoyer LC. Generation and release of DNA-binding vesicles by Haemophilus influenzae during induction and loss of competence. J Bacteriol 1982; 152: 855-864.
    • (1982) J Bacteriol , vol.152 , pp. 855-864
    • Deich, R.A.1    Hoyer, L.C.2
  • 15
    • 0020604645 scopus 로고
    • Identification and characterization of Campylobacter jejuni outer membrane proteins
    • Blaser MJ, Hopkins JA, Berka RM, Vasil ML, Wang WL. Identification and characterization of Campylobacter jejuni outer membrane proteins. Infect Immun 1983; 42: 276-284.
    • (1983) Infect Immun , vol.42 , pp. 276-284
    • Blaser, M.J.1    Hopkins, J.A.2    Berka, R.M.3    Vasil, M.L.4    Wang, W.L.5
  • 16
    • 0027513975 scopus 로고
    • Specific and nonspecific responses of murine B cells to membrane blebs of Borrelia burgdorferi
    • Whitmire WM, Garon CF. Specific and nonspecific responses of murine B cells to membrane blebs of Borrelia burgdorferi. Infect Immun 1993; 61: 1460-1467.
    • (1993) Infect Immun , vol.61 , pp. 1460-1467
    • Whitmire, W.M.1    Garon, C.F.2
  • 17
    • 0029009438 scopus 로고
    • Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: A novel mechanism of enzyme secretion
    • Kadurugamuwa JL, Beveridge TJ. Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: a novel mechanism of enzyme secretion. J Bacteriol 1995; 177: 3998-4008.
    • (1995) J Bacteriol , vol.177 , pp. 3998-4008
    • Kadurugamuwa, J.L.1    Beveridge, T.J.2
  • 18
    • 0023622882 scopus 로고
    • High incidence of Campylobacter-like organisms in endoscopic biopsies from patients with gastritis, with or without peptic ulcer
    • Fiocca R, Villani L, Turpini F, Solcia E. High incidence of Campylobacter-like organisms in endoscopic biopsies from patients with gastritis, with or without peptic ulcer. Digestion 1987; 38: 234-244.
    • (1987) Digestion , vol.38 , pp. 234-244
    • Fiocca, R.1    Villani, L.2    Turpini, F.3    Solcia, E.4
  • 19
    • 0009642895 scopus 로고
    • The mucosal response to Helicobacter pylori infection and its contribution to gastric pathology
    • Solcia E, Villani L, Luinetti O, Trespi E, Fiocca R. The mucosal response to Helicobacter pylori infection and its contribution to gastric pathology. Microecol Ther 1995; 25: 121-132.
    • (1995) Microecol Ther , vol.25 , pp. 121-132
    • Solcia, E.1    Villani, L.2    Luinetti, O.3    Trespi, E.4    Fiocca, R.5
  • 20
    • 0026739795 scopus 로고
    • Purification and characterization of the vacuolating toxin from Helicobacter pylori
    • Cover TL, Blaser MJ. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem 1992; 267: 10 570-10 575.
    • (1992) J Biol Chem , vol.267 , pp. 10570-10575
    • Cover, T.L.1    Blaser, M.J.2
  • 21
    • 0029740061 scopus 로고    scopus 로고
    • Significance of ammonia in the genesis of gastric epithelial lesions induced by Helicobacter pylori: An in vitro study with different bacterial strains and urea concentrations
    • Sommi P, Ricci V, Fiocca R, et al. Significance of ammonia in the genesis of gastric epithelial lesions induced by Helicobacter pylori: an in vitro study with different bacterial strains and urea concentrations. Digestion 1996; 57: 299-304.
    • (1996) Digestion , vol.57 , pp. 299-304
    • Sommi, P.1    Ricci, V.2    Fiocca, R.3
  • 22
    • 0027214170 scopus 로고
    • Cytotoxicity of Helicobacter pylori on human gastric epithelial cells in vitro: Role of cytotoxin(s) and ammonia
    • Ricci V, Sommi P, Fiocca R, et al. Cytotoxicity of Helicobacter pylori on human gastric epithelial cells in vitro: role of cytotoxin(s) and ammonia. Eur J Gastroenterol Hepatol 1993; 5: 687-694.
    • (1993) Eur J Gastroenterol Hepatol , vol.5 , pp. 687-694
    • Ricci, V.1    Sommi, P.2    Fiocca, R.3
  • 23
    • 0023917084 scopus 로고    scopus 로고
    • Human cell line for study of damage to gastric epithelial cell in vitro
    • Romano M, Razandi M, Sekhon S, Krause WJ, Ivey KJ. Human cell line for study of damage to gastric epithelial cell in vitro. J Lab Clin Med 1998; 111: 430-440.
    • (1998) J Lab Clin Med , vol.111 , pp. 430-440
    • Romano, M.1    Razandi, M.2    Sekhon, S.3    Krause, W.J.4    Ivey, K.J.5
  • 24
    • 0014333167 scopus 로고
    • Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide and 'postfixation' in uranyl acetate
    • Hirsch JG, Fedorko ME. Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide and 'postfixation' in uranyl acetate. J Cell Biol 1968; 38: 615-627.
    • (1968) J Cell Biol , vol.38 , pp. 615-627
    • Hirsch, J.G.1    Fedorko, M.E.2
  • 25
    • 0027464718 scopus 로고
    • Cathepsin E in follicle associated epithelium of intestine and tonsils: Localization to M cells and possible role in antigen processing
    • Finzi G, Cornaggia M, Capella C, et al. Cathepsin E in follicle associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing. Histochemistry 1993; 99: 201-211.
    • (1993) Histochemistry , vol.99 , pp. 201-211
    • Finzi, G.1    Cornaggia, M.2    Capella, C.3
  • 26
    • 0028879245 scopus 로고
    • Helicobacter pylori cytotoxin: Importance of native conformation for induction of neutralizing antibodies
    • Manetti R, Massari P, Burroni D, et al. Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies. Infect Immun 1995; 63: 4476-4480.
    • (1995) Infect Immun , vol.63 , pp. 4476-4480
    • Manetti, R.1    Massari, P.2    Burroni, D.3
  • 27
    • 0027434697 scopus 로고
    • Membrane traffic wardens and protein secretion in Gram-negative bacteria
    • Salmond GPC, Reeves P. Membrane traffic wardens and protein secretion in Gram-negative bacteria. Trends Biochem Sci 1993; 18: 7-11.
    • (1993) Trends Biochem Sci , vol.18 , pp. 7-11
    • Salmond, G.P.C.1    Reeves, P.2
  • 28
    • 0030478233 scopus 로고    scopus 로고
    • Pili, peptidases and protein secretion: Curious connections
    • Salmond GPC. Pili, peptidases and protein secretion: curious connections. Trends Microbiol 1996; 12: 474-476.
    • (1996) Trends Microbiol , vol.12 , pp. 474-476
    • Salmond, G.P.C.1
  • 29
    • 0030835739 scopus 로고    scopus 로고
    • The complete genome sequence of the gastric pathogen Helicobacter pylori
    • Tomb JF, White O, Kerlavage AR, et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997; 388: 539-547.
    • (1997) Nature , vol.388 , pp. 539-547
    • Tomb, J.F.1    White, O.2    Kerlavage, A.R.3
  • 30
    • 0031751816 scopus 로고    scopus 로고
    • Persistence of Helicobacter pylori VacA toxin and vacuolating potential in cultured gastric epithelial cells
    • Sommi P, Ricci V, Fiocca R, et al. Persistence of Helicobacter pylori VacA toxin and vacuolating potential in cultured gastric epithelial cells. Am J Physiol 1998; 275: G681-G688.
    • (1998) Am J Physiol , vol.275
    • Sommi, P.1    Ricci, V.2    Fiocca, R.3
  • 31
    • 0029838654 scopus 로고    scopus 로고
    • Determinants of Helicobacter pylori pathogenicity
    • Labigne A, de Reuse H. Determinants of Helicobacter pylori pathogenicity. Infect Agents Dis 1996; 5: 191-202.
    • (1996) Infect Agents Dis , vol.5 , pp. 191-202
    • Labigne, A.1    De Reuse, H.2
  • 32
    • 0028067979 scopus 로고
    • Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments
    • Papini E, De Bernard M, Milia E, et al. Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments. Proc Natl Acad Sci USA 1994; 91: 9720-9724.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9720-9724
    • Papini, E.1    De Bernard, M.2    Milia, E.3
  • 33
    • 0030868990 scopus 로고    scopus 로고
    • Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers
    • Molinari M, Galli C, Norais N, et al. Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers. J Biol Chem 1997; 272: 25 339-25 344.
    • (1997) J Biol Chem , vol.272 , pp. 25339-25344
    • Molinari, M.1    Galli, C.2    Norais, N.3
  • 34
    • 0026548007 scopus 로고
    • Adherence and internalization of Helicobacter pylori by Hep-2 cells
    • Evans DG, Evans DJ, Graham Y. Adherence and internalization of Helicobacter pylori by Hep-2 cells. Gastroenterology 1992; 102: 1557-1567.
    • (1992) Gastroenterology , vol.102 , pp. 1557-1567
    • Evans, D.G.1    Evans, D.J.2    Graham, Y.3
  • 35
    • 0025057448 scopus 로고
    • Possible evidence of invasiveness of Helicobacter pylori
    • Andersen L, Holck S. Possible evidence of invasiveness of Helicobacter pylori. Eur J Clin Microbiol Infect Dis 1990; 9: 135-138.
    • (1990) Eur J Clin Microbiol Infect Dis , vol.9 , pp. 135-138
    • Andersen, L.1    Holck, S.2
  • 36
    • 0028610509 scopus 로고
    • Electron microscopic study of association between Helicobacter pylori and gastric and duodenal mucosa
    • Noach LA, Rolf TM, Tytgat GNJ. Electron microscopic study of association between Helicobacter pylori and gastric and duodenal mucosa. J Clin Pathol 1994; 47: 699-704.
    • (1994) J Clin Pathol , vol.47 , pp. 699-704
    • Noach, L.A.1    Rolf, T.M.2    Tytgat, G.N.J.3
  • 37
    • 0022553348 scopus 로고
    • Campylobacter-like organisms and surface epithelium abnormalities in active, chronic gastritis in humans: An ultrastructural study
    • Tricottet V, Bruneval P, Vire O, et al. Campylobacter-like organisms and surface epithelium abnormalities in active, chronic gastritis in humans: an ultrastructural study. Ultrastruct Pathol 1986; 10: 113-122.
    • (1986) Ultrastruct Pathol , vol.10 , pp. 113-122
    • Tricottet, V.1    Bruneval, P.2    Vire, O.3
  • 38
    • 0028117801 scopus 로고
    • Epithelial cytotoxicity, immune responses, and inflammatory components of Helicobacter pylori gastritis
    • Fiocca R, Luinetti O, Villani L, Chiaravalli AM, Capella C, Solcia E. Epithelial cytotoxicity, immune responses, and inflammatory components of Helicobacter pylori gastritis. Scand J Gastroenterol 1994; 29 (Suppl 205): 11-21.
    • (1994) Scand J Gastroenterol , vol.29 , Issue.205 SUPPL. , pp. 11-21
    • Fiocca, R.1    Luinetti, O.2    Villani, L.3    Chiaravalli, A.M.4    Capella, C.5    Solcia, E.6
  • 39
    • 0026627852 scopus 로고
    • Macromolecular transport by rat gastric mucosa
    • Curtis GH, Gall DH. Macromolecular transport by rat gastric mucosa. Am J Physiol 1992; 262: G1033-G1039.
    • (1992) Am J Physiol , vol.262
    • Curtis, G.H.1    Gall, D.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.