메뉴 건너뛰기




Volumn 18, Issue 2, 2004, Pages 189-198

HIV-1 Nef protein in the nucleus influences adipogenesis as well as viral transcription through the peroxisome proliferator-activated receptors

Author keywords

Fatty acids; HIV 1; Lipids; Long terminal repeats; Nef; Nutrition; Peroxisome proliferator activated receptors

Indexed keywords

FATTY ACID; NEF PROTEIN; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; VIRUS PROTEIN;

EID: 1342289537     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200401230-00007     Document Type: Article
Times cited : (46)

References (30)
  • 1
    • 0034736521 scopus 로고    scopus 로고
    • Retroviruses in foreign species and the problem of provirus silencing
    • Svoboda J, Hejinar J, Geryk J, Elleder D, Vernerova Z. Retroviruses in foreign species and the problem of provirus silencing. Gene 2000, 261:181-188.
    • (2000) Gene , vol.261 , pp. 181-188
    • Svoboda, J.1    Hejinar, J.2    Geryk, J.3    Elleder, D.4    Vernerova, Z.5
  • 2
    • 0033396957 scopus 로고    scopus 로고
    • Fat distribution and metabolic changes in patients with HIV infection
    • Safrin S, Grunfeld C. Fat distribution and metabolic changes in patients with HIV infection. AIDS 1999, 13:2493-2505.
    • (1999) AIDS , vol.13 , pp. 2493-2505
    • Safrin, S.1    Grunfeld, C.2
  • 4
    • 0035056911 scopus 로고    scopus 로고
    • Peroxisomal proliferator activity legand therapy for HIV lipodiestrophy
    • Smith KJ, Skelton HC. Peroxisomal proliferator activity legand therapy for HIV lipodiestrophy. Clin Exp Dermatol 2001, 26:155-161.
    • (2001) Clin Exp Dermatol , vol.26 , pp. 155-161
    • Smith, K.J.1    Skelton, H.C.2
  • 5
    • 0037053290 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects
    • Hayes MM, Lane BR, King SR, Markovitz DM, Coffey MJ. Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects. J Biol Chem 2002, 277:16913-16919.
    • (2002) J Biol Chem , vol.277 , pp. 16913-16919
    • Hayes, M.M.1    Lane, B.R.2    King, S.R.3    Markovitz, D.M.4    Coffey, M.J.5
  • 6
    • 0028804160 scopus 로고
    • Genomic structure of an attenuated quasi-species of HIV-1 from a blood transfusion donor and recipients
    • Deacon NJ, Tsykin A, Solomon A, Smith K, Lundford-Menting M, Hooker DJ, et al. Genomic structure of an attenuated quasi-species of HIV-1 from a blood transfusion donor and recipients. Science 1995, 27:988-991.
    • (1995) Science , vol.27 , pp. 988-991
    • Deacon, N.J.1    Tsykin, A.2    Solomon, A.3    Smith, K.4    Lundford-Menting, M.5    Hooker, D.J.6
  • 7
    • 0033519616 scopus 로고    scopus 로고
    • Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1 - A report from the Sydney Blood Bank Cohort
    • Learmont JC, Geczy AF, Mills J, Ashton LJ, Raynes-Greenow CH, Garsia RJ, et al. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1 - A report from the Sydney Blood Bank Cohort. N Engl J Med 1999, 340:1715-1722.
    • (1999) N Engl J Med , vol.340 , pp. 1715-1722
    • Learmont, J.C.1    Geczy, A.F.2    Mills, J.3    Ashton, L.J.4    Raynes-Greenow, C.H.5    Garsia, R.J.6
  • 8
    • 0030991739 scopus 로고    scopus 로고
    • Vaccine effect using a live attenuated nef-deficient simian immunodeficiency virus of African green monkeys in the absence of detectable vaccine virus replication in vivo
    • Beer B, Baier M, Megede JZ, Norley S, Kurth R. Vaccine effect using a live attenuated nef-deficient simian immunodeficiency virus of African green monkeys in the absence of detectable vaccine virus replication in vivo. Proc Natl Acad Sci USA 1998, 94:4062-4067.
    • (1998) Proc Natl Acad Sci USA , vol.94 , pp. 4062-4067
    • Beer, B.1    Baier, M.2    Megede, J.Z.3    Norley, S.4    Kurth, R.5
  • 9
    • 0342505323 scopus 로고    scopus 로고
    • Pathogenic conversion of live-attenuated SIV vaccines is associated with expression of truncated nef
    • Sawai ET, Hamza MS, Ye M, Shaw KE, Luciw PA. Pathogenic conversion of live-attenuated SIV vaccines is associated with expression of truncated nef. J Virol 2000, 74:2038-2045.
    • (2000) J Virol , vol.74 , pp. 2038-2045
    • Sawai, E.T.1    Hamza, M.S.2    Ye, M.3    Shaw, K.E.4    Luciw, P.A.5
  • 10
    • 0028246191 scopus 로고
    • Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity
    • Jamieson BD, Aldovandi GM, Planelles V, Jowett JBM, Gao L, Bloch LM, et al. Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity. J Virol 1994, 6:3478-3485.
    • (1994) J Virol , vol.6 , pp. 3478-3485
    • Jamieson, B.D.1    Aldovandi, G.M.2    Planelles, V.3    Jowett, J.B.M.4    Gao, L.5    Bloch, L.M.6
  • 11
    • 0034948709 scopus 로고    scopus 로고
    • Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
    • Simmons A, Aluvihare V, McMichael A. Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity 2001, 14:763-777.
    • (2001) Immunity , vol.14 , pp. 763-777
    • Simmons, A.1    Aluvihare, V.2    McMichael, A.3
  • 14
    • 0029021083 scopus 로고
    • A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice
    • Shockett P, Difilippantonio M, Hellman N, Schatz D. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proc Natl Acad Sci USA 1995, 92:6522-6526.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6522-6526
    • Shockett, P.1    Difilippantonio, M.2    Hellman, N.3    Schatz, D.4
  • 15
    • 0036445530 scopus 로고    scopus 로고
    • Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication
    • Yamamoto T, Omoto S, Mizuguchi M, Mizukami H, Okuyama H, Okada N, et al. Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication. Microbiol Immunol 2002, 46:809-817.
    • (2002) Microbiol Immunol , vol.46 , pp. 809-817
    • Yamamoto, T.1    Omoto, S.2    Mizuguchi, M.3    Mizukami, H.4    Okuyama, H.5    Okada, N.6
  • 16
    • 0034812726 scopus 로고    scopus 로고
    • Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation
    • Fang J-Y, Mikovits JA, Bagni R, Petrow-Sadowski CL, Ruscetti FW. Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation. J Virol 2001, 75:9753-9761.
    • (2001) J Virol , vol.75 , pp. 9753-9761
    • Fang, J.-Y.1    Mikovits, J.A.2    Bagni, R.3    Petrow-Sadowski, C.L.4    Ruscetti, F.W.5
  • 17
    • 0033815873 scopus 로고    scopus 로고
    • Extracellular Nef of HIV-1 can target CD4 memory T population
    • Otake K, Ohta M, Minowada J, Hatama S, Takahashi A, Ikemoto A, et al. Extracellular Nef of HIV-1 can target CD4 memory T population. AIDS 2000, 14:1662-1664.
    • (2000) AIDS , vol.14 , pp. 1662-1664
    • Otake, K.1    Ohta, M.2    Minowada, J.3    Hatama, S.4    Takahashi, A.5    Ikemoto, A.6
  • 18
    • 0033542740 scopus 로고    scopus 로고
    • Induction of interleukin-15 production by HIV-1 Nef protein: A role in the proliferation of uninfected cells
    • Quaranta MG, Camponeschi B, Straface E, Malorini W, Viora M. Induction of interleukin-15 production by HIV-1 Nef protein: a role in the proliferation of uninfected cells. Exp Cell Res 1999, 250:112-121.
    • (1999) Exp Cell Res , vol.250 , pp. 112-121
    • Quaranta, M.G.1    Camponeschi, B.2    Straface, E.3    Malorini, W.4    Viora, M.5
  • 19
    • 0027146286 scopus 로고
    • Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell line
    • Murti KG, Brown PS, Ratner L, Garcia V. Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell line. Proc Natl Acad Sci USA 1993, 90:11895-11899.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11895-11899
    • Murti, K.G.1    Brown, P.S.2    Ratner, L.3    Garcia, V.4
  • 20
    • 0028252718 scopus 로고
    • Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines
    • Ranki A, Lagerstedt A, Ovod V, Aavik E, Krohn KJ. Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines. Arch Virol 1994, 139:365-378.
    • (1994) Arch Virol , vol.139 , pp. 365-378
    • Ranki, A.1    Lagerstedt, A.2    Ovod, V.3    Aavik, E.4    Krohn, K.J.5
  • 21
    • 0025328487 scopus 로고
    • A novel T-cell protein which recognizes a palindromic sequence in the negative regulatory element of the human immunodeficiency virus long terminal repeat
    • Orchard K, Perkins N, Chapman C, Harris J, Emery V, Goodwin G, et al. A novel T-cell protein which recognizes a palindromic sequence in the negative regulatory element of the human immunodeficiency virus long terminal repeat. J Virol 1990, 64:3234-3239.
    • (1990) J Virol , vol.64 , pp. 3234-3239
    • Orchard, K.1    Perkins, N.2    Chapman, C.3    Harris, J.4    Emery, V.5    Goodwin, G.6
  • 22
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000, 405:421-424.
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 23
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, Griglio S, Antonucci M, Torra I, Delerive P, Majd Z, et al. Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998, 273:25573-25580.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3    Torra, I.4    Delerive, P.5    Majd, Z.6
  • 24
    • 0027436026 scopus 로고
    • Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages
    • Murphy KM, Sweet MJ, Ross IL, Hume DA. Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages. J Virol 1993, 67:6956-6964.
    • (1993) J Virol , vol.67 , pp. 6956-6964
    • Murphy, K.M.1    Sweet, M.J.2    Ross, I.L.3    Hume, D.A.4
  • 25
    • 0029879580 scopus 로고    scopus 로고
    • Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-kappaB and Sp1 binding elements
    • Ilyinskii PO, Desrosiers RC. Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-kappaB and Sp1 binding elements. J Virol 1996, 70:3118-3126.
    • (1996) J Virol , vol.70 , pp. 3118-3126
    • Ilyinskii, P.O.1    Desrosiers, R.C.2
  • 26
    • 0033599038 scopus 로고    scopus 로고
    • Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
    • Barroso I, Gurnell M, Crowley VEF, Agostini M, Schwabe JW, Soos MA, et al. Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 1999, 402:880-883.
    • (1999) Nature , vol.402 , pp. 880-883
    • Barroso, I.1    Gurnell, M.2    Crowley, V.E.F.3    Agostini, M.4    Schwabe, J.W.5    Soos, M.A.6
  • 28
    • 0031964791 scopus 로고    scopus 로고
    • Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease
    • Hanna Z, Kay DG, Cool M, Jothy S, Rebai N, Jolicoeur P. Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease. J Virol 1998, 72:121-132.
    • (1998) J Virol , vol.72 , pp. 121-132
    • Hanna, Z.1    Kay, D.G.2    Cool, M.3    Jothy, S.4    Rebai, N.5    Jolicoeur, P.6
  • 29
    • 0032538278 scopus 로고    scopus 로고
    • Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
    • Hanna Z, Kay DG, Rebai N, Guimond A, Jothy S, Jolicoeur P. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 1998, 95:163-175.
    • (1998) Cell , vol.95 , pp. 163-175
    • Hanna, Z.1    Kay, D.G.2    Rebai, N.3    Guimond, A.4    Jothy, S.5    Jolicoeur, P.6
  • 30
    • 0034725614 scopus 로고    scopus 로고
    • The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation
    • Cohen GB, Rangan VS, Chen BJ, Smith S, Baltimore D. The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation. J Biol Chem 2000, 275:23097-23105.
    • (2000) J Biol Chem , vol.275 , pp. 23097-23105
    • Cohen, G.B.1    Rangan, V.S.2    Chen, B.J.3    Smith, S.4    Baltimore, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.