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Volumn 250, Issue 1, 1999, Pages 112-121

Induction of interleukin-15 production by HIV-1 Nef protein: A role in the proliferation of uninfected cells

Author keywords

Cell activation; HIV 1; IL 15; Nef protein

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 6; NEF PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033542740     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4494     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 0025977609 scopus 로고
    • HIV-1: The infective process in vivo
    • McCune J. M. HIV-1: The infective process in vivo. Cell. 64:1991;351-363.
    • (1991) Cell , vol.64 , pp. 351-363
    • McCune, J.M.1
  • 2
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphotropic virus type III (HTLV-III)
    • Arya S. K., Guo C., Josephs S. F., Wong-Staal F. Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science. 229:1985;69-73.
    • (1985) Science , vol.229 , pp. 69-73
    • Arya, S.K.1    Guo, C.2    Josephs, S.F.3    Wong-Staal, F.4
  • 3
    • 0028173343 scopus 로고
    • The role of Nef in the replication cycles of the human and simian immunodeficiency viruses
    • Cullen B. R. The role of Nef in the replication cycles of the human and simian immunodeficiency viruses. Virology. 205:1994;1-6.
    • (1994) Virology , vol.205 , pp. 1-6
    • Cullen, B.R.1
  • 4
    • 0025727523 scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines
    • Maitra R. K., Ahmad N., Holland S. M., Venkatesan S. Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines. Virology. 182:1991;522-533.
    • (1991) Virology , vol.182 , pp. 522-533
    • Maitra, R.K.1    Ahmad, N.2    Holland, S.M.3    Venkatesan, S.4
  • 5
    • 0347497008 scopus 로고
    • Human immunodeficiency virus type 1 negative factor is a transcriptional silencer
    • Niederman T. M. J., Thielan B. J., Ratner L. Human immunodeficiency virus type 1 negative factor is a transcriptional silencer. Proc. Natl. Acad. Sci. USA. 86:1989;1128-1132.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1128-1132
    • Niederman, T.M.J.1    Thielan, B.J.2    Ratner, L.3
  • 6
    • 0028006247 scopus 로고
    • The Human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller M. D., Warmerdam M. T., Gaston I., Greene W. C., Feinberg M. B. The Human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179:1994;101-113.
    • (1994) J. Exp. Med. , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 8
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the Nef gene
    • Daniel M. D., Kirchhoff F., Czajak S. C., Sehgal P. K., Desrosiers R. C. Protective effects of a live attenuated SIV vaccine with a deletion in the Nef gene. Science. 258:1992;1938-1941.
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Czajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 9
    • 0030576919 scopus 로고    scopus 로고
    • Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells
    • Fujii Y., Otake K., Tashiro M., Adachi A. Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells. FEBS Lett. 393:1996;93-96.
    • (1996) FEBS Lett. , vol.393 , pp. 93-96
    • Fujii, Y.1    Otake, K.2    Tashiro, M.3    Adachi, A.4
  • 13
    • 0029866832 scopus 로고    scopus 로고
    • Human immune response to HIV-1 Nef. II. Induction of HIV-1/HIV-2 Nef cross-reactive cytotoxic T lymphocytes of non-infected healthy individuals
    • Lucchiari-Hartz M., Bauer M., Niedermann G., Maier B., Meyerhans A., Eichmann K. Human immune response to HIV-1 Nef. II. Induction of HIV-1/HIV-2 Nef cross-reactive cytotoxic T lymphocytes of non-infected healthy individuals. Int. Immunol. 8:1996;577-584.
    • (1996) Int. Immunol. , vol.8 , pp. 577-584
    • Lucchiari-Hartz, M.1    Bauer, M.2    Niedermann, G.3    Maier, B.4    Meyerhans, A.5    Eichmann, K.6
  • 14
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins K. L., Chen B. K., Kalams S. A., Walker B. D., Baltimore D. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature. 391:1998;397-401.
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1    Chen, B.K.2    Kalams, S.A.3    Walker, B.D.4    Baltimore, D.5
  • 15
    • 0027533215 scopus 로고
    • Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
    • Skowronski J., Parks D., Mariani R. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J. 12:1993;703-713.
    • (1993) EMBO J. , vol.12 , pp. 703-713
    • Skowronski, J.1    Parks, D.2    Mariani, R.3
  • 16
    • 0028298767 scopus 로고
    • Nef protein of HIV-1 has B-cell stimulatory activity
    • Chirmule N., Oyaizu N., Saxinger C., Pahwa S. Nef protein of HIV-1 has B-cell stimulatory activity. AIDS. 8:1994;733-739.
    • (1994) AIDS , vol.8 , pp. 733-739
    • Chirmule, N.1    Oyaizu, N.2    Saxinger, C.3    Pahwa, S.4
  • 17
    • 0028178855 scopus 로고
    • Identification of an HIV-1 nef peptide that binds to HLA class II antigens
    • Torres B. A., Johnson M. H. Identification of an HIV-1 nef peptide that binds to HLA class II antigens. Biochem. Biophys. Res. Commun. 200:1994;1059-1065.
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 1059-1065
    • Torres, B.A.1    Johnson, M.H.2
  • 18
    • 0029987271 scopus 로고    scopus 로고
    • Replication of HIV-1 in human peripheral blood mononuclear cells activated by exogenous nef
    • Torres B. A., Tanabe T., Johnson M. H. Replication of HIV-1 in human peripheral blood mononuclear cells activated by exogenous nef. AIDS. 10:1996;1042-1043.
    • (1996) AIDS , vol.10 , pp. 1042-1043
    • Torres, B.A.1    Tanabe, T.2    Johnson, M.H.3
  • 19
    • 0028887886 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines
    • Greenway A. L., Azad A., McPhee D. A. Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. J. Virol. 69:1995;1842-1850.
    • (1995) J. Virol. , vol.69 , pp. 1842-1850
    • Greenway, A.L.1    Azad, A.2    McPhee, D.A.3
  • 20
    • 0024338667 scopus 로고
    • Normal human intestinal lymphocytes. Increased activation compared with the peripheral blood
    • Peters M. G., Secrist H., Anders K. R., Nash G. S., Rich S. R., MacDermott R. P. Normal human intestinal lymphocytes. Increased activation compared with the peripheral blood. J. Clin. Invest. 83:1989;1827-1833.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1827-1833
    • Peters, M.G.1    Secrist, H.2    Anders, K.R.3    Nash, G.S.4    Rich, S.R.5    MacDermott, R.P.6
  • 22
    • 0030032290 scopus 로고    scopus 로고
    • Induction and regulation of IL-15 expression in murine macrophages
    • Doherty T. M., Seder R. A., Sher A. Induction and regulation of IL-15 expression in murine macrophages. J. Immunol. 156:1996;735-741.
    • (1996) J. Immunol. , vol.156 , pp. 735-741
    • Doherty, T.M.1    Seder, R.A.2    Sher, A.3
  • 23
    • 0030008255 scopus 로고    scopus 로고
    • Interleukin (IL)15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I R region/IL-15 fusion message that lacks many upstream AUGs that normally attenuate IL-15 mRNA translation
    • Bamford R. N., Battiata A., Burton J. D., Sharma H., Waldmannm T. Interleukin (IL)15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I R region/IL-15 fusion message that lacks many upstream AUGs that normally attenuate IL-15 mRNA translation. Proc. Natl. Acad. Sci. USA. 93:1996;2897-2902.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2897-2902
    • Bamford, R.N.1    Battiata, A.2    Burton, J.D.3    Sharma, H.4    Waldmannm, T.5
  • 24
    • 0028363597 scopus 로고
    • Nef 27, but not the nef 25 isoform of human immunodeficiency virus-type pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells
    • Greenway A. L., McPhee D. A., Grgacic E., Hewish D., Lucantoni A., Macreadie I., Azad A. Nef 27, but not the nef 25 isoform of human immunodeficiency virus-type pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells. Virology. 198:1994;245-256.
    • (1994) Virology , vol.198 , pp. 245-256
    • Greenway, A.L.1    McPhee, D.A.2    Grgacic, E.3    Hewish, D.4    Lucantoni, A.5    Macreadie, I.6    Azad, A.7
  • 25
    • 0026077650 scopus 로고
    • Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA
    • Luria S., Chambers I., Berg P. Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA. Proc. Natl. Accad. Sci. USA. 88:1991;5326-5330.
    • (1991) Proc. Natl. Accad. Sci. USA , vol.88 , pp. 5326-5330
    • Luria, S.1    Chambers, I.2    Berg, P.3
  • 26
    • 0030027765 scopus 로고    scopus 로고
    • Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression
    • Collette Y., Chang H. L., Cerdan C., Chambost H., Algarte M., Mawas C., Imbert J., Burny A., Olive D. Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression. J. Immunol. 156:1996;360-370.
    • (1996) J. Immunol. , vol.156 , pp. 360-370
    • Collette, Y.1    Chang, H.L.2    Cerdan, C.3    Chambost, H.4    Algarte, M.5    Mawas, C.6    Imbert, J.7    Burny, A.8    Olive, D.9
  • 27
    • 0028798403 scopus 로고
    • IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation
    • Armitage R. J., Macduff B. M., Eisenman J., Paxton R., Grabstein K. H. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J. Immunol. 154:1995;483-487.
    • (1995) J. Immunol. , vol.154 , pp. 483-487
    • Armitage, R.J.1    Macduff, B.M.2    Eisenman, J.3    Paxton, R.4    Grabstein, K.H.5
  • 29
    • 0029147357 scopus 로고
    • Cytokine interactions in human immunodeficiency virus-infected individuals: Roles of interleukin (IL)-2, IL-12 and IL-15
    • Seder R. A., Grabstein K. H., Berzofsky J. A., McDyer J. F. Cytokine interactions in human immunodeficiency virus-infected individuals: Roles of interleukin (IL)-2, IL-12 and IL-15. J. Exp. Med. 182:1995;1067-1078.
    • (1995) J. Exp. Med. , vol.182 , pp. 1067-1078
    • Seder, R.A.1    Grabstein, K.H.2    Berzofsky, J.A.3    McDyer, J.F.4
  • 30
    • 0028818320 scopus 로고
    • Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-γ By natural killer cells in vitro
    • Carson W. E., Ross M. E., Baiocchi R. A., Marien M. J., Boiani N., Grabstein K., Caliguri M. A. Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-γ by natural killer cells in vitro. J. Clin. Invest. 96:1995;2578-2582.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2578-2582
    • Carson, W.E.1    Ross, M.E.2    Baiocchi, R.A.3    Marien, M.J.4    Boiani, N.5    Grabstein, K.6    Caliguri, M.A.7
  • 32
    • 44949266148 scopus 로고
    • Immunopathogenic mechanisms of HIV-infection: Cytokine induction of HIV expression
    • Rosemberg Z. F., Fauci A. Immunopathogenic mechanisms of HIV-infection: Cytokine induction of HIV expression. Immunol. Today. 11:1990;176-180.
    • (1990) Immunol. Today , vol.11 , pp. 176-180
    • Rosemberg, Z.F.1    Fauci, A.2
  • 33
    • 0029805203 scopus 로고    scopus 로고
    • Host factors and the pathogenesis of HIV-induced disease
    • Fauci A. S. Host factors and the pathogenesis of HIV-induced disease. Nature. 384:1996;529-532.
    • (1996) Nature , vol.384 , pp. 529-532
    • Fauci, A.S.1
  • 34
    • 0002433573 scopus 로고
    • Role of cytokines in the pathogenesis of human immunodeficiency virus infection
    • B. B. Aggarwal, & R. K. Puri. Cambridge: Blackwell Scientific
    • Poli G., Fauci A. S. Role of cytokines in the pathogenesis of human immunodeficiency virus infection. Aggarwal B. B., Puri R. K. Human Cytokines: Their Role in Disease and Therapy. 1995;421-435 Blackwell Scientific, Cambridge.
    • (1995) Human Cytokines: Their Role in Disease and Therapy , pp. 421-435
    • Poli, G.1    Fauci, A.S.2
  • 35
    • 0032521474 scopus 로고    scopus 로고
    • Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcγ receptors and expression of monokines
    • Swapan K., Chettemgere D., Venkateshan N. S., Seth P., Gajd-usek C., Clarence D., Gibbs J. Jr. Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcγ receptors and expression of monokines. Blood. 6:1998;2108-2117.
    • (1998) Blood , vol.6 , pp. 2108-2117
    • Swapan, K.1    Chettemgere, D.2    Venkateshan, N.S.3    Seth, P.4    Gajd-Usek, C.5    Clarence, D.6    Gibbs J., Jr.7
  • 36
    • 0026511126 scopus 로고
    • The effect of cytokines and pharmacologic agents on chronic HIV infection
    • Poli G., Fauci A. S. The effect of cytokines and pharmacologic agents on chronic HIV infection. AIDS Res. Hum. Retroviruses. 8:1992;191-195.
    • (1992) AIDS Res. Hum. Retroviruses , vol.8 , pp. 191-195
    • Poli, G.1    Fauci, A.S.2
  • 37
    • 0030587823 scopus 로고    scopus 로고
    • IL-15 stimulates the expansion of AIDS virus-specific CTL
    • Kanai T., Thomas E. K., Yasutomi Y., Letvin N. L. IL-15 stimulates the expansion of AIDS virus-specific CTL. J. Immunol. 157:1996;3681-3687.
    • (1996) J. Immunol. , vol.157 , pp. 3681-3687
    • Kanai, T.1    Thomas, E.K.2    Yasutomi, Y.3    Letvin, N.L.4
  • 38
    • 0030852135 scopus 로고    scopus 로고
    • Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization
    • Fackler O. T., Kienzle N., Kremmer E., Boese A., Schramm B., Klimkait T., Kucherer C., Mueller-Lantzsch N. Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization. Eur. J. Biochem. 247:1997;843-851.
    • (1997) Eur. J. Biochem. , vol.247 , pp. 843-851
    • Fackler, O.T.1    Kienzle, N.2    Kremmer, E.3    Boese, A.4    Schramm, B.5    Klimkait, T.6    Kucherer, C.7    Mueller-Lantzsch, N.8
  • 40
    • 0030014162 scopus 로고    scopus 로고
    • Producer-cell modification of human immunodeficiency virus type 1:Nef is a virion protein
    • Pandori M. W., Fitch N. J. S., Craig H. M., Richmann D. D., Spina C. A., Guatelli J. C. Producer-cell modification of human immunodeficiency virus type 1:Nef is a virion protein. J. Virol. 70:1996;4283-4290.
    • (1996) J. Virol. , vol.70 , pp. 4283-4290
    • Pandori, M.W.1    Fitch, N.J.S.2    Craig, H.M.3    Richmann, D.D.4    Spina, C.A.5    Guatelli, J.C.6
  • 41
    • 0029975546 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase
    • Welker R., Kottler H., Kalbitzer H. R., Krausslich H.-G. Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase. Virology. 219:1996;228-236.
    • (1996) Virology , vol.219 , pp. 228-236
    • Welker, R.1    Kottler, H.2    Kalbitzer, H.R.3    Krausslich, H.-G.4
  • 43
    • 0014354930 scopus 로고
    • Purification of lymphocytes and platelets by gradient centrifugation
    • Peper R. J., Tina W. Z., Mickelson M. M. Purification of lymphocytes and platelets by gradient centrifugation. J. Lab. Clin. Med. 72:1968;842-846.
    • (1968) J. Lab. Clin. Med. , vol.72 , pp. 842-846
    • Peper, R.J.1    Tina, W.Z.2    Mickelson, M.M.3
  • 44
    • 0017646342 scopus 로고
    • Isolation and functional characterization of human mucosal lymphoid cells
    • Bull D. M., Bookmann M. A. Isolation and functional characterization of human mucosal lymphoid cells. J. Clin. Invest. 59:1977;966-974.
    • (1977) J. Clin. Invest. , vol.59 , pp. 966-974
    • Bull, D.M.1    Bookmann, M.A.2
  • 46
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynsky P., Sacchi N. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynsky, P.1    Sacchi, N.2
  • 47
    • 0029040243 scopus 로고
    • Down-regulation of interleukin-2 receptor gene activation and protein expression by dideoxynucleoside analogs
    • Viora M., Camponeschi B. Down-regulation of interleukin-2 receptor gene activation and protein expression by dideoxynucleoside analogs. Cell. Immunol. 163:1995;289-295.
    • (1995) Cell. Immunol. , vol.163 , pp. 289-295
    • Viora, M.1    Camponeschi, B.2
  • 48
    • 0028899725 scopus 로고
    • Differential modulation of Th1- And Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein
    • Haraguchi S., Good R. A., James-Yarish M., Cianciolo G. J. Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein. Proc. Natl. Acad. Sci. USA. 92:1995;3611-3615.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3611-3615
    • Haraguchi, S.1    Good, R.A.2    James-Yarish, M.3    Cianciolo, G.J.4


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