Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450

Drug Metabolism and Disposition

Volumn 32, Issue 3, 2004, Pages 305-313

  Miller, Kristy K Michael ^a   Cai, Jian ^a   Ripp, Sharon L ^a,c   Pierce Jr , William M ^a   Rushmore, Thomas H ^b   Prough, Russell A ^a  

^a University of Louisville School of Medicine   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; PRASTERONE;

AEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; FETUS; GAS CHROMATOGRAPHY; HAMSTER; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY; SWINE;

ANIMALS; CRICETINAE; CYTOCHROME P-450 ENZYME SYSTEM; DEHYDROEPIANDROSTERONE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYLATION; MALE; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; STEREOISOMERISM; SWINE;

ANIMALIA; CRICETINAE; SUS SCROFA;

EID: 1342281163     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.3.305     Document Type: Article

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