Preservation of neurological functions by nitric oxide synthase inhibitors following hemorrhagic shock

Neuropharmacology

Volumn 44, Issue 2, 2003, Pages 244-252

  Ng, Kian Chye ^a   Moochhala, Shabbir M ^a   Md, Shirhan ^b   Yap, Ee Lin ^a   Low, Siew Yang ^b   Lu, Jia ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY AGENCY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Hemorrhagic shock; iNOS inhibitor; MABP; Neurological functions; Rat

Indexed keywords

CANAVANINE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD GAS; BRAIN DEGENERATION; BRAIN FUNCTION; BRAIN PROTECTION; CONTROLLED STUDY; HEMORRHAGIC SHOCK; HISTOLOGY; MALE; MEAN ARTERIAL PRESSURE; NEUROLOGIC DISEASE; NONHUMAN; PERFORMANCE; PRESERVATION; PRIORITY JOURNAL; RAT; RESUSCITATION; SPECIES COMPARISON; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0037293982     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00368-4     Document Type: Article

References (26)

1. Carrillo P., Takasu A., Safar P., Tisherman S., Stezoski S.W., Stolz G., Dixon C.E., Radovsky A. Prolonged severe hemorrhagic shock and resuscitation in rats does not cause subtle brain damage. Journal of Trauma. 45:(2):1998;239-249.
2. Cash D., Beech J.S., Rayne R.C., Bath P.M., Meldrum B.S., Williams S.C. Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Research. 905:2001;91-103.
3. Cobbs C.S., Fenoy A., Bredt D.S., Noble L.J. Expression of nitric oxide synthase in the cerebral microvasculature after traumatic brain injury in the rat. Brain Research. 751:1997;336-338.
4. Dalkara T., Moskowitz M.A. The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia. Brain Pathology. 4:(1):1994;49-57.
5. Dawson T.M., Snyder S.H. Gases as biological messengers: nitric oxide and carbon monoxide in the brain. Journal of Neuroscience. 14:(9):1994;5147-5159.
6. Harbrecht B.G., Wu B., Watkins S.C., Billiar T.R., Peitzman A.B. Inhibition of nitric oxide synthase during severe shock but not after resuscitation increase hepatic injury and neutrophil accumulation in hemorrhaged rats. Shock. 8:(6):1997;415-421.
7. Hua T.C., Moochhala S.M. Influence of L-arginine, aminoguanidine and NG-nitro- L-arginine methyl ester on the survival rate in a rat model of hemorrhagic shock. Shock. 11:1999;51-57.
8. Iadecola C., Zhang F., Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. American Journal of Physiology. 268:1995;R286-R292.
9. Janigro D., West G.A., Nguyen T.S., Winn H.R. Regulation of blood-brain barrier endothelial cells by nitric oxide. Circulation Research. 75:1994;528-538.
10. Kawase M., Kinouchi H., Kato I., Akabane A., Kondo T., Arai S., Fujimura M., Okamoto H., Yohimoto T. Inducible nitric oxide synthase following hypoxia in rat cultured glial cells. Brain Research. 738:1996;319-322.
11. Kilbourn R.G., Szabo C., Traber D.L. Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: Lessons learned from experimental and clinical studies. Shock. 7:(4):1997;235-246.
12. Kline J.A., Thornton L.R., Lopaschuk G.D., Barbee R.W., Watts J.A. Heart function after severe hemorrhagic shock. Shock. 12:(6):1999;454-461.
13. Kobari M., Fukuuchi Y., Tomita M., Tanahashi N., Takeda H. Role of nitric oxide in regulation of cerebral microvascular tone and autoregulation of cerebral blood flow in cats. Brain Research. 667:1994;255-262.
14. Levin H.S. Prediction of recovery from traumatic brain injury. Journal of Neurotrauma. 12:1995;913-922.
15. Liaudet L., Feihl F., Rosselet A., Markert M., Hurni J.M., Perret C. Beneficial effects of L-canavanine, a selective inhibitor of iNOS, during rodent endotoxaemia. Clinical Science. 90:(5):1996;369-377.
16. Liaudet L., Soriano F.G., Szabo C. Biology of nitric oxide signaling. Critical Care Medicine. 28:(4 (Suppl)):2000;N37-N52.
17. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacology Review. 43:(2):1991;109-141.
18. Robert G.K., Szabo C., Daniel L.T. Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies. Shock. 4:(7):1997;235-246.
19. Shapira Y., Shohami E., Sidi A., Soffer D., Freeman S., Cotev S. Experimental closed-head injury in rats: mechanical, pathologic and neurological properties. Critical Care Medicine. 16:(3):1988;258-265.
20. Sullivan S.J., Ornstein A.E., Swaine B.R. Agreement of classification decisions using two measures of motor coordination in persons with a traumatic brain injury. Brain Injury. 8:1994;613-621.
21. Szabo C. Alterations in nitric oxide production in various forms of circulatory shock. New Horizons. 3:(1):1995;2-23.
22. Szabo C., Thiemermann C. Invited opinion: Role of NO in hemorrhagic, traumatic and anaphylactic shock and in thermal injury. Shock. 2:(2):1994;145-155.
23. Umans J.G., Samsel R.W. L-canavanine selectively augments contraction in aortas from endotoxemic rats. European Journal of Pharmacology. 210:(3):1992;343-346.
24. Wei G., Dawson V.L., Zweier J.L. Role of neuronal and endothelia nitric oxide synthase in nitric oxide generation in the brain following cerebral ischemia. Biochimica et Biophysica Acta. 1455:(1):1999;23-34.
25. Zhang F.Y., Casey R.M., Ross M.E., Iadecola C. Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke. 27:1996;317-323.
26. Zingarelli B., Ischiropoulos H., Salzman A.L., Szabo C. Amelioration by mercaptoethylguanidine of the vascular and energetic failure in hemorrhagic shock in the anesthetized rat. European Journal of Pharmacology. 338:(1):1997;55-65.