The roles of ADP and TXA2 in botrocetin/VWF-induced aggregation of washed platelets

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 12, 2004, Pages 2213-2222

  Liu, J ^c   Pestina, T I ^a   Berndt, M C ^b   Steward, S A ^a   Jackson, C W ^a   Gartner, T K ^c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MEMPHIS   (United States)

Author keywords

ATP secretion; Botrocetin; Glycoprotein lb; TXB2 production; Von Willebrand factor

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BOTROCETIN; CALCIUM ION; PHOSPHOLIPASE A2; PROTEIN KINASE C; PURINE P2Y1 RECEPTOR; PURINE P2Y12 RECEPTOR; THROMBOXANE A2; VON WILLEBRAND FACTOR;

ARTICLE; BLOOD SAMPLING; CALCIUM TRANSPORT; CELL INTERACTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENOTYPE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; THROMBOCYTE AGGLUTINATION; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD PLATELETS; CALCIUM; CELL ADHESION; CROTALID VENOMS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PHOSPHOLIPASES A; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE C; QUINACRINE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; THROMBOXANE A2; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 13244284711     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.01023.x     Document Type: Article

References (37)

1. Sakariassen KS, Nievelstein PF, Coller BS, Sixma JJ. The role of platelet membrane glycoproteins Ib and IIb-IIIa in platelet adherence to human artery subendothelium. Br J Haematol 1986; 63: 681-91.
2. Nesbitt WS, Giuliano S, Kulkarni S, Dopheide SM, Harper IS, Jackson SP. Intercellular calcium communication regulates platelet aggregation and thrombus growth. J Cell Biol 2003; 160: 1151-61.
3. Moake JL, Turner NA, Stathopoulos NA, Nolasco L, Hellums JD. Shear-induced platelet aggregation can be mediated by vWf released from platelets, as well as by exogenous large or unusually large vWf multimers, requires adenosine diphosphate, and is resistant to aspirin. Blood 1988; 71: 1366-74.
4. Chow TW, Hellums JD, Moake JL, Kroll MH. Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation. Blood 1992; 80: 113-20.
5. Oda A, Yokoyama K, Murata M, Tokuhira M, Nakamura K, Handa M, Watanabe K, Ikeda Y. Protein tyrosine phosphorylation in human platelets during shear stress-induced platelet aggregation (SIPA) is regulated by glycoprotein (GP) Ib/IX as well as GP IIb/IIIa and requires intact cytoskeleton and endogenouse ADP. Thromb Haemost 1995; 74: 736-42.
6. Turner NA, Moake JL, McIntire LV. Blockade of adenosine diphosphate receptors P2Y12 and P2Y1 is required to inhibit aggregation in whole blood under flow. Blood 2001; 98: 3340-5.
7. Goto S, Tamura N, Eto K, Ikeda Y, Handa S. Functional significance of adenosine 5′-diphosphate receptor (P2Y12) in platelet activation initiated by binding of von Willebrand factor to platelet GPIbα induced by conditions of high shear. Circulation 2002; 105: 2531-6.
8. 3. J Biol Chem 2000; 275: 41377-88.
9. Canobbio I, Bertoni A, Lova P, Paganini S, Hirsch E, Sinigaglia F, Balduini C, Torti M. Platelet activation by von Willebrand factor requires coordinated signaling through thromboxane A2 and the FcγIIA receptor. J Biol Chem 2001; 276: 26022-9.
10. Read MS, Smith SV, Lamb MA, Brinkhous KM. Role of botrocetin in platelet agglutination: formation of an activated complex of botrocetin and von Willebrand factor. Blood 1989; 74: 1031-5.
11. Andrews RK, Booth WJ, Gorman JJ, Castaldi PA, Berndt MC. Purification of botrocetin from Brothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex. Biochem 1989; 28: 8317-26.
12. Thomas DW, Mannon RB, Mannon PJ, Latour A, Oliver JA, Hoffman M, Smithies O, Koller BH, Coffman TM. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. J Clin Invest 1998; 102: 1994-2001.
13. Offermanns S, Toombs CF, Hu Y-H, Simon MI. Defective platelet activation in Gαq-deficient mice. Nature 1997; 389: 183-6.
14. Hodivala-Dilke KM, McHugh KP, Tsakiris DA, Rayburn H, Crowley D, Ullman-Cullere M, Ross FP, Coller BS, Teitelbaum S, Hynes RO. β3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest 1999; 103: 229-38.
15. Boyer JL, Romero-Avila T, Schachter JB, Harden TK. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol 1996; 50: 1323-9.
16. Ingall AH, Dixon J, Bailey A, Coombs ME, Cox D, McInally JI, Hunt SF, Kindon ND, Teobald BJ, Willis PA, Humphries RG, Leff P, Clegg JA, Smith JA, Tomlinson W. Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy. J Med Chem 1999; 42 213-20.
17. Gralnick HR, Williams S, McKeown L, Kramer W, Krutzsch H, Gorecki M, Pinet A, Garfinkel LI. A monomeric von Willebrand factor fragment, Leu-504-Lys-728, inhibits von Willebrand factor interactions with glycoprotein Ib-IX [corrected]. Proc Natl Acad Sci USA 1992; 89: 7880-4. Erratum in: Proc Natl Acad Sci USA 1993; 90: 3118.
18. McGhie AI McNatt J, Ezov N, Cui K, Mower LK, Hagay Y, Buja LM, Garfinkel LI, Gorecki M, Willerson JT. Abolition of cyclic flow variations in stenosed, enothelium-injured coronary arteries in non-human primates with a peptide from human plasma von Willebrand factor-glycoprotein Ib binding domain. Circulation 1994; 90: 2976-81.
19. Slack SM, Jennings LK, Turitto VT. Platelet size distribution measurements as indicators of shear stress-induced aggregation. Ann Biomed Engr 1994; 22: 653-9.
20. Cho MJ, Liu J, Pestina TI, Steward SA, Jackson CW, Gartner TK. αIIbβ3-mediated outside-in signaling induced by the agonist peptide LSARLAF utilizes ADP and thromboxane A2 receptors to cause α-granule secretion by platelets. Thromb Haemost 2003; 1: 363-73.
21. Wall JE, Buijs-Wilts M, Arnold JT, Wang W, White MM, Jennings LK, Jackson CW. A flow cytometric assay using mepacrine for study of uptake and release of platelet dense granule contents. Br J Haematol 1995; 89: 380-5.
22. Cho MJ, Liu J, Pestina TI, Steward SA, Thomas DW, Coffman TM, Wang D, Jackson CW, Gartner TK. The roles of αIIbβ3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation. Blood 2003; 101: 2646-51.
23. Prevost N, Woulfe D, Tognolini M, Brass LF. Contact-dependent signaling during the late events of platelet activation. J Thromb Haemost 2003; 1: 1613-27.
24. Grabarek J, Raychowdhury M, Ravid K, Kent KC, Newman PJ, Ware JA. Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. J Biol Chem 1992; 267: 10011-7.
25. Baldassare JJ, Henderson PA, Burns D, Loomis C, Fischer GJ. Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. J Biol Chem 1992; 267: 15585-90.
26. Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of PKC-delta isoform in agonist-induced dense granule secretion in human platelets. J Biol Chem 2004; 279: 2360-7.
27. Balboa MA, Blasinde J, Jones SS, Dennis EA. Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells. J Biol Chem 1997; 272: 8576-80.
28. Hazen SL, Gross RW. Human myocardial cytosolic Ca2+-independent phospholipase A2 is modulated by ATP. Biochem J 1991; 280: 581-7.
29. Hirashima Y, Farooqui AA, Mills JS, Horrocks LA. Identification and purification of calcium-independent phospholipase N2 from bovine brain cytosol. J Neurochem 1992; 59: 708-14.
30. Portilla D, Dai G. Purification of a novel calcium-independent phospholipase A2 from rabbit kidney. J Biol Chem 1996; 271: 15451-7.
31. Haimovich B, Ji P, Ginalis E, Kramer R, Greco R. Phospholipase A2 enzymes regulate αIIbβ3-mediated, but not FcγRII receptor-mediated, pp125FAK phosphorylation in platelets. Thromb Haemost 1999; 81: 618-24.
32. Lehr M, Griessbach K. Involvement of different protein kinases and phospholipases A2 in phorbol ester (TPA)-induced arachidonic acid liberation in bovine platelets. Med Inflamm 2000; 9: 31-4.
33. Shattil SJ, Brass LF. Induction of the fibrinogen receptor on human platelets by intracellular mediators. J Biol Chem 1987; 262: 992-1000.
34. Quinton TM, Kim S, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. Biochem J 2002; 368: 535-43.
35. Klages B, Brandt U, Simon MI, Schultz G, Offermanns S. Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets. J Cell Biol 1999; 144: 745-54.
36. Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, Shattil SJ. Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. Blood 2004; 103: 3403-11.
37. Kroll MH, Hellums JD, Guo Z, Durante W, Razdan K, Hrbolich JK, Schafer AI. Protein kinase C is activated in platelets subjected to pathological shear stress. J Biol Chem 1993; 268: 3520-4.