메뉴 건너뛰기




Volumn 25, Issue 1, 2005, Pages 74-81

Benzene increases the ratio of arachidonic acids to docosahexaenoic acids and inhibits the de novo synthesis of ceramide in the rat liver

Author keywords

Arachidonic acids; Benzene; Ceramide; Docosahexaenoic acids; Fatty acids; Phospholipids; Sphingomyelin

Indexed keywords

ARACHIDONIC ACID; BENZENE; CERAMIDE; DOCOSAHEXAENOIC ACID; FATTY ACID; PHOSPHOLIPID; SATURATED FATTY ACID; SPHINGOMYELIN; UNSATURATED FATTY ACID;

EID: 13244278195     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.1042     Document Type: Article
Times cited : (1)

References (44)
  • 1
    • 0024423614 scopus 로고
    • Hematotoxicity and carcinogenecity of benzene
    • Aksoy M. 1989. Hematotoxicity and carcinogenecity of benzene. Environ. Health Perspect. 82: 193-197.
    • (1989) Environ. Health Perspect. , vol.82 , pp. 193-197
    • Aksoy, M.1
  • 2
    • 0002482959 scopus 로고    scopus 로고
    • Toxic effects of solvents and vapors
    • Amdur MO, Doull J, Klaassen CD (eds). McGraw-Hill: New York
    • Andrews LS, Snyder R. 2001. Toxic effects of solvents and vapors. In Toxicology, Amdur MO, Doull J, Klaassen CD (eds). McGraw-Hill: New York; 681-722.
    • (2001) Toxicology , pp. 681-722
    • Andrews, L.S.1    Snyder, R.2
  • 3
    • 0017363794 scopus 로고    scopus 로고
    • Effects of toluene on the metabolism, disposition and hemopoietic toxicity of benzene
    • Andrews LS, Lee EW, Witmer CM, Kocsis JJ, Snyder R. 1997. Effects of toluene on the metabolism, disposition and hemopoietic toxicity of benzene. Biochem. Phamacol. 26: 293-300.
    • (1997) Biochem. Phamacol. , vol.26 , pp. 293-300
    • Andrews, L.S.1    Lee, E.W.2    Witmer, C.M.3    Kocsis, J.J.4    Snyder, R.5
  • 4
    • 0022446460 scopus 로고
    • Effects of benzene inhalation on lymphocyte subpopulations and immune response in mice
    • Aoyama K. 1986. Effects of benzene inhalation on lymphocyte subpopulations and immune response in mice. Toxicol. Appl. Pharmacol. 85: 92-101.
    • (1986) Toxicol. Appl. Pharmacol. , vol.85 , pp. 92-101
    • Aoyama, K.1
  • 5
    • 0023876056 scopus 로고
    • Genotoxic effects of a sub-acute low-level inhalation exposure to a mixture of carcinogenic chemicals
    • Au WW, Ward JB, Jr, Ramanujam VM, Harper BL, Moslen MT, Legator MS. 1988. Genotoxic effects of a sub-acute low-level inhalation exposure to a mixture of carcinogenic chemicals. Mutat. Res. 203: 103-115.
    • (1988) Mutat. Res. , vol.203 , pp. 103-115
    • Au, W.W.1    Ward Jr., J.B.2    Ramanujam, V.M.3    Harper, B.L.4    Moslen, M.T.5    Legator, M.S.6
  • 6
    • 0025009255 scopus 로고
    • Cytogenetic assay in genotoxic studies: Somatic cell effects of benzene and germinal cell effects of dibromocholropropane
    • Au WW, Cantelli-Forti G, Hrelia P, Legator MS. 1990. Cytogenetic assay in genotoxic studies: somatic cell effects of benzene and germinal cell effects of dibromocholropropane. Teratogen. Carcinogen. Mutagen. 10: 125-134.
    • (1990) Teratogen. Carcinogen. Mutagen. , vol.10 , pp. 125-134
    • Au, W.W.1    Cantelli-Forti, G.2    Hrelia, P.3    Legator, M.S.4
  • 7
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 8
    • 0033931806 scopus 로고    scopus 로고
    • The putative benzene metabolite 2,3,5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells
    • Bratton SB, Lau SS, Monks TJ. 2000. The putative benzene metabolite 2,3,5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells. Chem. Res. Toxicol. 13: 550-556.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 550-556
    • Bratton, S.B.1    Lau, S.S.2    Monks, T.J.3
  • 9
    • 13244277279 scopus 로고
    • Unsaturated fatty acids; nutritional and physiological significance
    • Chapman & Hall: New York
    • British Nutrition Foundation Task Force. 1992. Unsaturated fatty acids; nutritional and physiological significance. Unsaturated Fatty Acids and Cancer. Chapman & Hall: New York; 120-128.
    • (1992) Unsaturated Fatty Acids and Cancer , pp. 120-128
  • 11
    • 0025764152 scopus 로고
    • Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis
    • Cave WT Jr. 1991. Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis. FASEB J. 5: 2160-2166.
    • (1991) FASEB J. , vol.5 , pp. 2160-2166
    • Cave Jr., W.T.1
  • 12
    • 0029985219 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fats and breast cancer
    • Cave WT Jr. 1996. Dietary omega-3 polyunsaturated fats and breast cancer. Nutrition 12: S39-S42.
    • (1996) Nutrition , vol.12
    • Cave Jr., W.T.1
  • 13
    • 0019766889 scopus 로고
    • Early changes of lymphocyte RNA and serum immunglobulins following chronic exposure to benzene
    • Chircu V, Lonescu M, Zgoanta C. 1981. Early changes of lymphocyte RNA and serum immunglobulins following chronic exposure to benzene. Med. Int. 19: 373-378.
    • (1981) Med. Int. , vol.19 , pp. 373-378
    • Chircu, V.1    Lonescu, M.2    Zgoanta, C.3
  • 15
    • 0027082723 scopus 로고
    • Downregulation of saturated fatty acid and upregulation of unsaturated fatty acid by 13-cis-retionic acid in human prostate cancer cells
    • Dahiya R, Park HD, Cassafer G, Cusick J, Narayan P. 1992. Downregulation of saturated fatty acid and upregulation of unsaturated fatty acid by 13-cis-retionic acid in human prostate cancer cells. Biochem. Int. 28: 981-987.
    • (1992) Biochem. Int. , vol.28 , pp. 981-987
    • Dahiya, R.1    Park, H.D.2    Cassafer, G.3    Cusick, J.4    Narayan, P.5
  • 16
    • 0025652155 scopus 로고
    • Gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs
    • Das UN. 1990. Gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs. Nutrition 6: 429-439.
    • (1990) Nutrition , vol.6 , pp. 429-439
    • Das, U.N.1
  • 20
    • 0030421091 scopus 로고    scopus 로고
    • Mechanisms of ceramide-mediated apoptosis
    • Hannun YA, Obeid LM. 1997. Mechanisms of ceramide-mediated apoptosis. Adv. Exp. Med. Biol. 407: 145-149.
    • (1997) Adv. Exp. Med. Biol. , vol.407 , pp. 145-149
    • Hannun, Y.A.1    Obeid, L.M.2
  • 21
    • 0019468897 scopus 로고
    • The detection of in vivo hematoxicity of benzene by in vitro liquid bone marrow cultures
    • Harigaya K, Miller ME, Cronkite EP, Drew RT. 1981. The detection of in vivo hematoxicity of benzene by in vitro liquid bone marrow cultures. Toxicol. Appl. Pharmacol. 60: 346-353.
    • (1981) Toxicol. Appl. Pharmacol. , vol.60 , pp. 346-353
    • Harigaya, K.1    Miller, M.E.2    Cronkite, E.P.3    Drew, R.T.4
  • 23
  • 25
    • 0025978394 scopus 로고
    • Hypothalamic-pituitary-adrenocortical axis activity and immune function after oral exposure to benzene and toluene
    • Hsieh GC, Sharma RP, Parker RD. 1991. Hypothalamic-pituitary- adrenocortical axis activity and immune function after oral exposure to benzene and toluene. Immunopharmacology. 21: 23-31.
    • (1991) Immunopharmacology , vol.21 , pp. 23-31
    • Hsieh, G.C.1    Sharma, R.P.2    Parker, R.D.3
  • 28
    • 0035957921 scopus 로고    scopus 로고
    • Induction of apoptosis through B-cell receptor cross-linking occurs via de nova generated C16-ceramide and involves mitochondria
    • Kroesen BJ, Pettus B, Luberto C, Busman M, Sietsma H, de Leij L, Hannun YA. 2002. Induction of apoptosis through B-cell receptor cross-linking occurs via de nova generated C16-ceramide and involves mitochondria. J. Biol. Chem. 276: 13606-13614.
    • (2002) J. Biol. Chem. , vol.276 , pp. 13606-13614
    • Kroesen, B.J.1    Pettus, B.2    Luberto, C.3    Busman, M.4    Sietsma, H.5    De Leij, L.6    Hannun, Y.A.7
  • 29
    • 0035912824 scopus 로고    scopus 로고
    • Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells
    • Liu G, Bibus DM, Bode AM, Ma WY, Holman RT, Dong Z. 2001. Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells. Proc. Natl. Acad. Sci. USA 98: 7510-7515.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7510-7515
    • Liu, G.1    Bibus, D.M.2    Bode, A.M.3    Ma, W.Y.4    Holman, R.T.5    Dong, Z.6
  • 30
    • 0024458311 scopus 로고
    • Benzene: An experimental multipotential caecinogen. Results of the long-term bioassays performed at the Bologna Institute of Oncology
    • Maltoni C, Ciliberti A, Cotti G, Conti B, Belpoggi F. 1989. Benzene: an experimental multipotential caecinogen. Results of the long-term bioassays performed at the Bologna Institute of Oncology. Environ. Health. Perspect. 82: 102-124.
    • (1989) Environ. Health. Perspect. , vol.82 , pp. 102-124
    • Maltoni, C.1    Ciliberti, A.2    Cotti, G.3    Conti, B.4    Belpoggi, F.5
  • 32
    • 0035656180 scopus 로고    scopus 로고
    • Docosahexaenoic acid related genes and transcription factors inducing apoptosis in human colon cancer cells
    • Narayanan BA, Narayanan NK, Reddy BS. 2001. Docosahexaenoic acid related genes and transcription factors inducing apoptosis in human colon cancer cells. Int. J. Oncol. 19: 1255-1262.
    • (2001) Int. J. Oncol. , vol.19 , pp. 1255-1262
    • Narayanan, B.A.1    Narayanan, N.K.2    Reddy, B.S.3
  • 34
    • 0034920774 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of gene expression
    • Ntambi JM, Bene H. 2001. Polyunsaturated fatty acid regulation of gene expression. J. Mol. Neurosci. 16: 273-278.
    • (2001) J. Mol. Neurosci. , vol.16 , pp. 273-278
    • Ntambi, J.M.1    Bene, H.2
  • 35
    • 0029195772 scopus 로고
    • Antitumor effects of alpha-linoleic acid on the human tumor transplanted in nude mice and the metastasis of Vx-7 tumor in rabbit
    • Numata M. 1995. Antitumor effects of alpha-linoleic acid on the human tumor transplanted in nude mice and the metastasis of Vx-7 tumor in rabbit. Hokkaido Igaku Zasshi-Hokkaido J. Med. Sci. 70: 183-193.
    • (1995) Hokkaido Igaku Zasshi-Hokkaido J. Med. Sci. , vol.70 , pp. 183-193
    • Numata, M.1
  • 36
    • 0027872294 scopus 로고
    • Benzene toxicity and risk assessment 1972-1992. Implications for future regulation
    • Paustenbach DB, Bass RD, Price P. 1993. Benzene toxicity and risk assessment. 1972-1992. Implications for future regulation. Environ. Health Perspect. Suppl. 101: 177-200.
    • (1993) Environ. Health Perspect. Suppl. , vol.101 , pp. 177-200
    • Paustenbach, D.B.1    Bass, R.D.2    Price, P.3
  • 37
    • 0028227122 scopus 로고
    • Early effects of benzene exposure in mice. Hematological versus genotoxic effects
    • Plappert U, Barthel E, Raddatz K, Seidel HJ. 1994. Early effects of benzene exposure in mice. Hematological versus genotoxic effects. Arch. Toxicol. 68: 284-290.
    • (1994) Arch. Toxicol. , vol.68 , pp. 284-290
    • Plappert, U.1    Barthel, E.2    Raddatz, K.3    Seidel, H.J.4
  • 38
    • 0030904906 scopus 로고    scopus 로고
    • Immunotoxico-logical effects of benzene inhalation in male Sprague-Dawley rats
    • Robinson SN, Shah R, Wong BA, Wong VA, Farris GM. 1997. Immunotoxico-logical effects of benzene inhalation in male Sprague-Dawley rats. Toxicology 119: 227-237.
    • (1997) Toxicology , vol.119 , pp. 227-237
    • Robinson, S.N.1    Shah, R.2    Wong, B.A.3    Wong, V.A.4    Farris, G.M.5
  • 39
    • 0035876962 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, melatonin and cancer prevention
    • Sauer LA, Dauchy RT, Blask DE. 2001. Polyunsaturated fatty acids, melatonin. and cancer prevention. Biochem. Pharmacol. 61: 1455-1462.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 1455-1462
    • Sauer, L.A.1    Dauchy, R.T.2    Blask, D.E.3
  • 40
    • 0026046826 scopus 로고
    • Potential role of free radicals in benzene-induced myelotoxicity and leukemia
    • Subrahmanyam VV, Ross D, Eastmond DA, Smith MT. 1991. Potential role of free radicals in benzene-induced myelotoxicity and leukemia. Fre Rad. Med. 11: 495-515.
    • (1991) Fre Rad. Med. , vol.11 , pp. 495-515
    • Subrahmanyam, V.V.1    Ross, D.2    Eastmond, D.A.3    Smith, M.T.4
  • 41
    • 0034631827 scopus 로고    scopus 로고
    • Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology
    • Tepper AD, Ruurs P, Wiedmer T, Sims PJ, Borst J, Van Blitterswijk WJ. 2000. Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology. J. Cell Biol. 150: 155-164.
    • (2000) J. Cell Biol. , vol.150 , pp. 155-164
    • Tepper, A.D.1    Ruurs, P.2    Wiedmer, T.3    Sims, P.J.4    Borst, J.5    Van Blitterswijk, W.J.6
  • 42
    • 0028009326 scopus 로고
    • Monitoring of benzene-exposed workers for genotoxic effects of benzene: Improved-working-condition-related decrease in the frequencies of chromosomal aberrations in peripheral blood lymphocytes
    • Tompa A, Major J, Jakab MG. 1994. Monitoring of benzene-exposed workers for genotoxic effects of benzene: improved-working-condition-related decrease in the frequencies of chromosomal aberrations in peripheral blood lymphocytes. Mutat. Res. 304: 159-165.
    • (1994) Mutat. Res. , vol.304 , pp. 159-165
    • Tompa, A.1    Major, J.2    Jakab, M.G.3
  • 43
    • 0030570557 scopus 로고    scopus 로고
    • Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: Reduction by CYP2E1 inhalation
    • Tuo J, Loft S, Thomsen MS, Poulsen HE. 1996. Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhalation. Mutat. Res. 368: 213-219.
    • (1996) Mutat. Res. , vol.368 , pp. 213-219
    • Tuo, J.1    Loft, S.2    Thomsen, M.S.3    Poulsen, H.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.