SEREX identification of new tumor antigens linked to melanoma-associated retinopathy

International Journal of Cancer

Volumn 114, Issue 1, 2005, Pages 88-93

  Hartmann, Tanja B ^a   Bazhin, Alexandr V ^a   Schadendorf, Dirk ^a   Eichmüller, Stefan B ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Antibody; Humoral immune response; Melanoma; Melanoma associated retinopathy; SEREX

Indexed keywords

COMPLEMENTARY DNA; GALECTIN 3; PROTEIN; RETINA S ANTIGEN; RHODOPSIN; RNA; SUSHI REPEAT CONTAINING PROTEIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; GENE; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; MELANOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL; TUMOR GROWTH;

ANTIGENS, NEOPLASM; BLOTTING, NORTHERN; CELL LINE, TUMOR; DNA, COMPLEMENTARY; DNA, NEOPLASM; GENE LIBRARY; HUMANS; MELANOMA; PARANEOPLASTIC SYNDROMES; RETINAL DISEASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHODOPSIN; RNA, NEOPLASM; SEROLOGIC TESTS; SKIN NEOPLASMS;

EID: 13244277577     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20762     Document Type: Article

References (60)

1. Bevona C, Sober AJ. Melanoma incidence trends. Dermatol Clin 2002;20:589-95.
2. Hall HI, Jamison P, Fulton JP, Clutter G, Roffers S, Parrish P. Reporting cutaneous melanoma to cancer registries in the United States. J Am Acad Dermatol 2003;49:624-30.
3. Stang A, Jockel KH. Changing patterns of skin melanoma mortality in West Germany from 1968 through 1999. Ann Epidemiol 2003;13:436-42.
4. Schadendorf D. Is there a standard for the palliative treatment of melanoma? Onkologie 2002;25:74-6.
5. Nestle F, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, Burg G, Schadendorf D. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 1998;4:269-70.
6. Sun Y, Paschen A, Schadendorf D. Cell-based vaccination against melanoma-background, preliminary results, and perspective. J Mol Med 1999;77:593-608.
7. 8+ T cells. J Exp Med 2003;198:569-80.
8. Hsu F, Caspar C, Czerwinski D, Kwak L, Liles T, Syrengelas A, Taidi-Laskowski B, Levy R. Tumor-specific idiotype vaccines in the treatment of patients with B-cell lymphoma long-term results of a clinical trial. Blood 1997;89:3129-35.
9. Overwijk WW, Restifo NP. Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other." Crit Rev Immunol 2000;20:433-50.
10. Keltner JL, Thirkill CE, Yip PT. Clinical and immunologic characteristics of melanoma-associated retinopathy syndrome: eleven new cases and a review of 51 previously published cases. J Neuroophthalmol 2001;21:173-87.
11. Kellner U, Bornfeld N, Foerster MH. Severe course of cutaneous melanoma associated paraneoplastic retinopathy. Br J Ophthalmol 1995;79:746-52.
12. Chan JW. Paraneoplastic retinopathies and optic neuropathies. Surv Ophthalmol 2003;48:12-38.
13. Milam AH, Saari JC, Jacobson SG, Lubinski WP, Feun LG, Alexander KR. Autoantibodies against retinal bipolar cells in cutaneous melanoma-associated retinopathy. Invest Ophthalmol Vis Sci 1993;34:91-100.
14. Lei B, Bush RA, Milam AH, Sieving PA. Human melanoma-associated retinopathy (MAR) antibodies alter the retinal ON-response of the monkey ERG in vivo. Invest Ophthalmol Vis Sci 2000;41:262-6.
15. Flynn M, Fishman G, Adamus G. Antiretinal Müller cell antibodies in patients with melanoma associated and autoimmune retinopathy. Invest Ophthalmol Vis Sci 2000;41:567.
16. Keltner JL, Thirkill CE. The 22-kDa antigen in optic nerve and retinal diseases. J Neuroophthalmol 1999;19:71-83.
17. Potter MJ, Adamus G, Szabo SM, Lee R, Mohaseb K, Behn D. Autoantibodies to transducin in a patient with melanoma-associated retinopathy. Am J Ophthalmol 2002;134:128-30.
18. Altman AJ, Baehner RL. Favorable prognosis for survival in children with coincident opso-myoclonus and neuroblastoma. Cancer 1976;37:846-52.
19. Hiyama E, Yokoyama T, Ichikawa T, Hiyama K, Kobayashi M, Tanaka Y, Ueda K, Yano H. Poor outcome in patients with advanced stage neuroblastoma and coincident opsomyoclonus syndrome. Cancer 1994;74:1821-6.
20. Maddison P, Newsom-Davis J, Mills KR, Souhami RL. Favourable prognosis in Lambert-Eaton myasthenic syndrome and small-cell lung carcinoma. Lancet 1999;353:117-8.
21. Rojas I, Graus F, Keime-Guibert F, Rene R, Delattre JY, Ramon JM, Dalmau J, Posner JB. Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies. Neurology 2000;55:713-5.
22. Chan C, O'Day J. Melanoma-associated retinopathy: does autoimmunity prolong survival? Clin Exp Ophthalmol 2001;29:235-8.
23. Eichmüller S, Usener D, Dummer R, Stein A, Thiel D, Schadendorf D. Serological detection of cutaneous T-cell lymphoma-associated antigens. Proc Natl Acad Sci USA 2001;98:629-34.
24. Alexander KR, Barnes CS, Fishman GA, Milam AH. Nature of the cone ON-pathway dysfunction in melanoma-associated retinopathy. Invest Ophthalmol Vis Sci 2002;43:1189-97.
25. Di Polo A, Farber DB. Rod photoreceptor-specific gene expression in human retinoblastoma cells. Proc Natl Acad Sci USA 1995;92:4016-20.
26. Badano JL, Ansley SJ, Leitch CC, Lewis RA, Lupski JR, Katsanis N. Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. Am J Hum Genet 2003;72:650-8.
27. Meindl A, Carvalho MR, Herrmann K, Lorenz B, Achatz H, Apfelstedt-Sylla E, Wittwer B, Ross M, Meitinger T. A gene (SRPX) encoding a sushi-repeat- containing protein is deleted in patients with X-linked retinitis pigmentosa. Hum Mol Genet 1995;4:2339-46.
28. Dinculescu A, McDowell JH, Amici SA, Dugger DR, Richards N, Hargrave PA, Smith WC. Insertional mutagenesis and immunochemical analysis of visual arrestin interaction with rhodopsin. J Biol Chem 2002;277:11703-8.
29. Adamus G, Chan CC. Experimental autoimmune uveitides: multiple antigens, diverse diseases. Int Rev Immunol 2002;21:209-29.
30. Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F. cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner. Oncogene 2002;21;6101-12.
31. Perillo NL, Marcus ME, Baum LG. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol Med 1998;76:402-12.
32. Rabinovich GA, Riera CM, Landa CA, Sotomayor CE. Galectins: a key intersection between glycobiology and immunology. Braz J Med Biol Res 1999;32:383-93.
33. Yang RY, Liu FT. Galectins in cell growth and apoptosis. Cell Mol Life Sci 2003;60:267-76.
34. Konstantinov KN, Robbins BA, Liu FT. Galectin-3, a beta-galactoside- binding animal lectin, is a marker of anaplastic large-cell lymphoma. Am J Pathol 1996;148:25-30.
35. Yoshimura A, Gemma A, Hosoya Y, Komaki E, Hosomi Y, Okano T, Takenaka K, Matuda K, Seike M, Uematsu K, Hibino S, Shibuya M, et al. Increased expression of the LGALS3 (galectin 3) gene in human non-small-cell lung cancer. Genes Chromosomes Cancer 2003;37:159-64.
36. Brustmann H, Riss D, Naude S. Galectin-3 expression in normal, hyperplastic, and neoplastic endometrial tissues. Pathol Res Pract 2003;199:151-8.
37. Takenaka Y, Inohara H, Yoshii T, Oshima K, Nakahara S, Akahani S, Honjo Y, Yamamoto Y, Raz A, Kubo T. Malignant transformation of thyroid follicular cells by galectin-3. Cancer Lett 2003;195:111-9.
38. Riss D, Jin L, Qian X, Bayliss J, Scheithauer BW, Young WF Jr, Vidal S, Kovacs K, Raz A, Lloyd RV. Differential expression of galectin-3 in pituitary tumors. Cancer Res 2003;63:2251-5.
39. Betka J, Plzak J, Smetana K Jr, Gabius HJ. Galectin-3, an endogenous lectin, as a tool for monitoring cell differentiation in head and neck carcinomas with implications for lectin-glycan functionality. Acta Otolaryngol 2003;123:261-3.
40. Uehara F, Ohba N, Ozawa M. Isolation and characterization of galectins in the mammalian retina. Invest Ophthalmol Vis Sci 2001;42:2164-72.
41. Cozens AL, Runswick MJ, Walker JE. DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J Mol Biol 1989;206:261-80.
42. Takekawa M, Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell 1998;95:521-30.
43. Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K, Dent P, Fisher PB. mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci USA 2002;99:10054-9.
44. Schmitz HD, Dutine C, Bereiter-Hahn J. Exportin 1-independent nuclear export of GAPDH. Cell Biol Int 2003;27:511-7.
45. Shestakova EA, Singer RH, Condeelis J. The physiological significance of beta-actin mRNA localization in determining cell polarity and directional motility. Proc Natl Acad Sci USA 2001;98:7045-50.
46. Zhu H, Qiu H, Yoon HW, Huang S, Bunn HF. Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells. Proc Natl Acad Sci USA 1999;96:14742-7.
47. Neumann CA, Krause DS, Carman CV, Das S, Dubey DP, Abraham JL, Bronson RT, Fujiwara Y, Orkin SH, Van Etten RA. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defense and tumour suppression. Nature 2003;424:561-5.
48. Goedert M, Crowther RA, Garner CC. Molecular characterization of microtubule-associated proteins tau and MAP2. Trends Neurosci 1991;14:193-9.
49. Arai T, Ikeda K, Akiyama H, Tsuchiya K, Iritani S, Ishiguro K, Yagishita S, Oda T, Odawara T, Iseki E. Different immunoreactivities of the microtubule-binding region of tau and its molecular basis in brains from patients with Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol (Berl) 2003;105:489-98.
50. Cheng MY, Hartl FU, Martin J, Pollock RA, Kalousek F, Neupert W, Hallberg EM, Hallberg RL, Horwich AL. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 1989;337:620-5.
51. Darnell RB, Posner JB. Paraneoplastic syndromes involving the nervous system. N Engl J Med 2003;349:1543-54.
52. Alexander KR, Fishman GA, Peachey NS, Marchese AL, Tso MO. "On" response defect in paraneoplastic night blindness with cutaneous malignant melanoma. Invest Ophthalmol Vis Sci 1992;33:477-83.
53. De Smet C, Lurquin C, Lethe B, Martelange V, Boon T. DNA methylation is the primary silencing mechanism for a set of germ line-and tumor-specific genes with a CpG-rich promoter. Mol Cell Biol 1999;19:7327-35.
54. Polans AS, Buczylko J, Crabb J, Palczewski K. A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy. J Cell Biol 1991;112:981-9.
55. Bazhin AV, Savchenko MS, Shifrina ON, Demoura SA, Chikina SY, Jaques G, Kogan EA, Chuchalin AG, Philippov PP. Recoverin as a paraneoplastic antigen in lung cancer: the occurrence of anti-recoverin autoantibodies in sera and recoverin in tumors. Lung Cancer 2004;44:193-8.
56. Maeda T, Imanishi Y, Palczewski K. Rhodopsin phosphorylation: 30 years later. Prog Retin Eye Res 2003;22:417-34.
57. Breitman ML, Tsuda M, Usukura J, Kikuchi T, Zucconi A, Khoo W, Shinohara T. Expression of S-antigen in retina, pineal gland, lens, and brain is directed by 5′-flanking sequences. J Biol Chem 1991;266:15505-10.
58. Miyashita Y, Moriya T, Kubota T, Yamada K, Asami K. Expression of opsin molecule in cultured murine melanocyte. J Invest Dermatol Symp Proc 2001;6:54-7.
59. Goidin D, Mamessier A, Staquet MJ, Schmitt D, Berthier-Vergnes O. Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations. Anal Biochem 2001;295:17-21.
60. Viola A, Lanzavecchia A. T cell activation determined by T cell receptor number and tunable thresholds. Science 1996;273:104-6.