From discrete protein kinetics to continuous Brownian dynamics: A new perspective

Protein Science

Volumn 11, Issue 1, 2002, Pages 1-5

  Qian, H ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Channel protein; Energy landscape; Folding; Force; Gating; Membrane potential

Indexed keywords

MEMBRANE PROTEIN;

AQUEOUS SOLUTION; CHANNEL GATING; ENERGY; FORCE; KINETICS; LIPID MEMBRANE; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; REVIEW;

KINETICS; LIGANDS; MODELS, CHEMICAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; THERMODYNAMICS;

EID: 0036135425     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.ps.18902     Document Type: Review

References (39)

1. + channels: II. The components of gating currents and a model of channel activation
2. Pulsed H/D-exchange studies of folding intermediates
3. The nature of protein folding pathways: The classical versus the new view
4. Diffusion theory and discrete rate constants in ion permeation
5. Denatured states of proteins
6. Local interactions and the optimization of protein folding
7. Kinetics of the opening and closing of individual excitability-inducing material channels in a lipid bilayer
8. Computing the field in proteins and channels
9. Dynamic strength of molecular adhesion bonds
10. Stretching single molecules into novel conformations using the atomic force microscope
11. Adhesion forces between individual ligand-receptor pairs
12. The energy landscapes and motions of proteins
13. Diffusion-limited contact formation in unfolded cytochrome c: Estimating the maximum rate of protein folding
14. Reaction-rate theory: Fifty years after Kramers
15. Brownian motion in a field of force and the diffusion model of chemical reactions
16. Dynamics of proteins: Elements and function
17. Folding-unfolding transitions in single titin molecules characterized with laser tweezers
18. Direct NMR evidence for an intermediate preceding the rate-limiting step in the unfolding of ribonuclease A
19. Comparison of experimental binding data and theoretical models in proteins containing subunits
20. Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy
21. On the nature of allosteric transition: A plausible model
22. Intermolecular forces and energetics between ligands and receptors
23. The burst phase in ribonuclease A folding and solvent dependence of the unfolded state
24. Thermodynamic hierarchy and local energetics of folded proteins
25. Hydrogen exchange kinetics of proteins in denaturants: A generalized two-process model
26. A graphical method for force analysis: Macromolecular mechanics with atomic force microscopy
27. Reversible unfolding of individual titin immunoglobulin domains by AFM
28. A quantitative analysis of single protein-ligand complex separation with the atomic force microscope
29. Hysteresis in force probe measurements: A dynamic systems perspective
30. Kramers' diffusion theory applied to gating kinetics of voltage-dependent ion channels
31. Molecular collapse: The rate-limiting step in two-state cytochrome c folding
32. Early events in voltage gating
33. First passage time approach to diffusion controlled reactions
34. A sequential model of nucleation-dependent protein folding: Kinetic studies of ribonuclease A
35. Elasticity and unfolding of single molecules of the giant muscle protein titin
36. Navigating the folding routes
37. Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme
38. Simple model of protein folding kinetics