Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria

BMC Biotechnology

Volumn 4, Issue , 2004, Pages

  Porzio, Stefano ^a   Bossù, Paola ^b   Ruggiero, Paolo ^c   Boraschi, Diana ^d   Tagliabue, Aldo ^e,f  

^a Inpharzam Ricerche SA   (Switzerland)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c CHIRON VACCINES   (Italy)

^d INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^e ALTA Srl   (Italy)

^f International Vaccine Institute   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; GENETIC ENGINEERING; LIVING SYSTEMS STUDIES; VACCINES;

BIOLOGICAL ACTIVITY; CYTOKINES; DISTAL COLONS; MUCOSAL DELIVERY;

BACTERIA;

ENDOTOXIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; RECOMBINANT PROTEIN; ANTIINFLAMMATORY AGENT; IL1RN PROTEIN, HUMAN; IL1RN PROTEIN, MOUSE; INTERLEUKIN 1; SIALOGLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOLYSIS; BACILLUS SUBTILIS; BACTERIAL STRAIN; COLON MUCOSA; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DEATH; DESCENDING COLON; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG INSTILLATION; DRUG MEGADOSE; DRUG RELEASE; FEMALE; FEVER; GENETIC ENGINEERING; HYPOGLYCEMIA; IN VIVO STUDY; INTESTINE LAVAGE; METABOLIC DISORDER; MOUSE; NEUTROPHILIA; NONHUMAN; RABBIT; RAT; SHOCK; SPOROGENESIS; ANIMAL; BACTERIAL SPORE; BLOOD; GENETICS; HUMAN; INTESTINE MUCOSA; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA; BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BACILLUS SUBTILIS; FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; INTESTINAL MUCOSA; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIALOGLYCOPROTEINS; SPORES, BACTERIAL;

EID: 13244252314     PISSN: 14726750     EISSN: None     Source Type: Journal    
DOI: 10.1186/1472-6750-4-27     Document Type: Article

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