Therapy of mucosal candidiasis by expression of an anti-idiotype in human commensal bacteria

Nature Biotechnology

Volumn 18, Issue 10 SUPPL., 2000, Pages 1060-1064

  Beninati, Concetta ^a,b   Oggioni, Marco Rinaldo ^a   Boccanera, Maria ^c   Spinosa, Maria Rita ^a   Maggi, Tiziana ^a   Conti, Stefania ^d   Magliani, Walter ^d   De Bernardis, Flavia ^c   Teti, Giuseppe ^b   Cassone, Antonio ^c   Pozzi, Gianni ^a   Polonelli, Luciano ^d  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

Author keywords

Engineered commensal bacteria; Microbicidal scfv delivery; Mucosal colonization; Therapeutic treatment; Vaginal candidiasis

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; FLUCONAZOLE; IMMUNOGLOBULIN IDIOTYPE; MYCOTOXIN; RECOMBINANT PROTEIN; ANTIIDIOTYPIC ANTIBODY; SCFVH6 ANTIBODY; SINGLE CHAIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BACTERIAL COUNT; CANDIDA ALBICANS; CANDIDIASIS; CHEMISTRY; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; INTRAVAGINAL DRUG ADMINISTRATION; MICROBIOLOGY; PASSIVE IMMUNIZATION; PHYSIOLOGY; PROTEIN ENGINEERING; RAT; STREPTOCOCCUS; VAGINITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; BACTERIAL GENE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; FUNGUS GROWTH; GENETIC ENGINEERING; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOCOCCUS GORDONII; TREATMENT OUTCOME; VAGINA CANDIDIASIS;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; FEMALE; FLUCONAZOLE; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN IDIOTYPES; MYCOTOXINS; PROTEIN ENGINEERING; RATS; RECOMBINANT PROTEINS; STREPTOCOCCUS; VAGINITIS;

EID: 0033623253     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/80250     Document Type: Article

References (7)

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