Synthesis and DNA topoisomerase-II inhibitory activity of unnatural nucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 1, 2005, Pages 15-35

  Mishra, Ram Chandra ^a   Dwivedi, Namrata ^a   Tripathi, Rama Pati ^a   Bansal, Iti ^a   Saxena, Jitendra Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Aza pyrimidines; Brugia malayi; DNA topoisomerase II; Glycosylated amino ester; Nucleosides

Indexed keywords

5 BROMO 1 [ETHYL(2' O ACETYL 3' O BENZYL 5',6'DIDEOXY 5' N 4 NITROBENZOYLAMINO BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 5 BROMO 1 [ETHYL(2' O ACETYL 5',6' DIDEOXY 3' O METHYL 5' N 4 NITROBENZOYLAMINO ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 5 BROMO 1 [ETHYL(2' O ACETYL 5',6' DIDEOXY 3' O METHYL 5' N 4 NITROBENZOYLAMINO BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 5 BROMO 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 5 BROMO 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 6 [2 (DIMETHYLAMINO)ETHYLAMINO] 3 HYDROXY 7H INDENO[2,1 C]QUINOLIN 7 ONE; 6 AZA 1 [ETHYL (2' O ACETYL 3' O BENZYL 5',6' DIDEOXY 5' N 4 NITROBENZOYLAMINO BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 3' O BENZYL 5' N 3 CHLOROBENZOYLAMINO 5',6' DIDEOXY ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL]URACIL; 6 AZA 1 [ETHYL(2' O ACETYL 3' O BENZYL 5' N 3 CHLOROBENZOYLAMINO 5',6' DIDEOXY BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL]URACIL; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 3 CHLOROBENZOYLAMINO 5',6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 3 CHLOROBENZOYLAMINO 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 4 NITROBENZOYLAMINO 5' 6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL]URACIL; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 4 NITROBENZOYLAMINO 5' 6' DIDEOXY 3' O METHYL ALPHA DEXTRO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 4 NITROBENZOYLAMINO 5' 6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N 4 NITROBENZOYLAMINO 5' 6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL]URACIL; 6 AZA 1 [ETHYL(2' O ACETYL 5' N BENZYLAMINO 5',6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N BENZYLAMINO 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5' N CYCLOPROPYLAMINO 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 6 AZA 1 [ETHYL(2' O ACETYL 5',6' DIDEOXY 5' N FURYLAMINO 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5',6' DIDEOXY 5' N FURYLAMINO 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(2' O ACETYL 5',6' DIDEOXY 5' N HEXADECYLAMINO 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 3' O BENZYL 5',6' DIDEOXY BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 3' O BENZYL 5',6' DIDEOXY BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL ALPHA DEXTRO GLUCO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]THYMINE; 6 AZA 1 [ETHYL(5' N ACETYLAMINO 2' O ACETYL 5',6' DIDEOXY 3' O METHYL BETA LEVO IDO HEPTO 1',4' FURANURONAT 1' YL)]URACIL; DNA TOPOISOMERASE (ATP HYDROLYSING); ISOMERASE INHIBITOR; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; BRUGIA MALAYI; CATALYSIS; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FILARIA; HYDROLYSIS; NONHUMAN; POLYMERIZATION; SILYLATION;

ACETATES; AMMONIA; CATALYSIS; DNA TOPOISOMERASES, TYPE II; HYDROLYSIS; METHANOL; NUCLEOSIDES; PYRIMIDINES; TIN COMPOUNDS;

BRUGIA; BRUGIA MALAYI; FILARIA;

EID: 13144274708     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-200046776     Document Type: Article

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