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Volumn 5, Issue 2, 1998, Pages 351-354

Role of epidermal growth factor receptor overexpression, K-ras point mutation and c-myc amplification in the carcinogenesis of non-small cell lung cancer

Author keywords

C myc; Epidermal growth factor receptor; K ras; Lung cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ONCOPROTEIN; RAS PROTEIN;

EID: 13144257716     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.5.2.351     Document Type: Article
Times cited : (20)

References (31)
  • 1
    • 0001013823 scopus 로고    scopus 로고
    • Molecular biology of cancer: The cell cycle
    • Devita VT, Hellman S and Rosenberg SA (eds.) 5th edition, Lippincott-Raven Publishers, Philadelphia
    • Kastan MB: Molecular biology of cancer: The cell cycle. In: Cancer Principles & Practice of Oncology. Devita VT, Hellman S and Rosenberg SA (eds.) 5th edition, Lippincott-Raven Publishers, Philadelphia, pp121-134, 1997.
    • (1997) Cancer Principles & Practice of Oncology , pp. 121-134
    • Kastan, M.B.1
  • 2
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A and Schlessinger J: Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203-212, 1990.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 3
    • 0026316096 scopus 로고
    • Growth factors and cancer
    • Aaronson SA: Growth factors and cancer. Science 254: 1146-1153, 1991.
    • (1991) Science , vol.254 , pp. 1146-1153
    • Aaronson, S.A.1
  • 6
    • 0022647432 scopus 로고
    • The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity
    • Akiyama T, Sudo C, Ogawara H, Toyoshima K and Yamamoto T: The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity. Science 232: 1644-1646, 1986.
    • (1986) Science , vol.232 , pp. 1644-1646
    • Akiyama, T.1    Sudo, C.2    Ogawara, H.3    Toyoshima, K.4    Yamamoto, T.5
  • 7
    • 0004728997 scopus 로고
    • Growth factors and pulmonary epithelia
    • Brody JS, Center DM and Tkachuk VA (eds.) Marcel Dekker Inc., New York
    • Ryan RM and Finkelstein JN: Growth factors and pulmonary epithelia. In: Signal Transduction in Lung Cells. Brody JS, Center DM and Tkachuk VA (eds.) Marcel Dekker Inc., New York, pp263-291, 1993.
    • (1993) Signal Transduction in Lung Cells , pp. 263-291
    • Ryan, R.M.1    Finkelstein, J.N.2
  • 9
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • Rusch V, Baselga J, Cordon-Cardo C, Orazem J, Zaman M, Hoda S, McIntosh J, Kurie J and Dmitrovsky E: Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 53: 2379-2385, 1993.
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3    Orazem, J.4    Zaman, M.5    Hoda, S.6    McIntosh, J.7    Kurie, J.8    Dmitrovsky, E.9
  • 11
    • 0025293818 scopus 로고
    • Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products
    • Suzuki Y, Orita M, Shiraishi M, Hayashi K and Sekiya T: Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 5: 1037-1043, 1990.
    • (1990) Oncogene , vol.5 , pp. 1037-1043
    • Suzuki, Y.1    Orita, M.2    Shiraishi, M.3    Hayashi, K.4    Sekiya, T.5
  • 13
    • 0026680448 scopus 로고
    • Clinical significance of ras oncosene activation in human lung cancer
    • Rodenhuis S and Slebos RJC: Clinical significance of ras oncosene activation in human lung cancer. Cancer Res 52 (Suppl): 2665s-2669s, 1992.
    • (1992) Cancer Res , vol.52 , Issue.SUPPL.
    • Rodenhuis, S.1    Slebos, R.J.C.2
  • 14
    • 0022994280 scopus 로고
    • Proliferative response and oncogene expression induced by epidermal growth factor in EL2 rat fibroblasts
    • Liboi E, Pelosi E, Testa U, Peschle C and Rossi GB. Proliferative response and oncogene expression induced by epidermal growth factor in EL2 rat fibroblasts. Mol Cell Biol 6: 2275-2278, 1986.
    • (1986) Mol Cell Biol , vol.6 , pp. 2275-2278
    • Liboi, E.1    Pelosi, E.2    Testa, U.3    Peschle, C.4    Rossi, G.B.5
  • 15
    • 0024306478 scopus 로고
    • Induction of c-fos and c-myc proto-oncogene expression by epidermal growth factor and transforming growth factor alpha is calcium-independent
    • Cutry AF, Kinniburgh AJ, Krabak MJ, Hui S-W and Wenner CE: Induction of c-fos and c-myc proto-oncogene expression by epidermal growth factor and transforming growth factor alpha is calcium-independent. J Biol Chem 264: 19700-19705, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 19700-19705
    • Cutry, A.F.1    Kinniburgh, A.J.2    Krabak, M.J.3    Hui, S.-W.4    Wenner, C.E.5
  • 16
    • 0022372361 scopus 로고
    • Heparin-treated, v-myc-transformed chicken heart mesenchymal cells assume a normal morphology but are hypersensitive to epidermal growth factor (EGF) and brain fibroblast growth factor (bFGF); cells transformed by the v-Ha-ras oncogene are refractory to EGF and bFGF but are hypersensitive to insulin-like growth factors
    • Balk SD, Riley TM. Gunther HS and Morisi A: Heparin-treated, v-myc-transformed chicken heart mesenchymal cells assume a normal morphology but are hypersensitive to epidermal growth factor (EGF) and brain fibroblast growth factor (bFGF); cells transformed by the v-Ha-ras oncogene are refractory to EGF and bFGF but are hypersensitive to insulin-like growth factors. Proc Natl Acad Sci USA 82: 5781-5785, 1985.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5781-5785
    • Balk, S.D.1    Riley, T.M.2    Gunther, H.S.3    Morisi, A.4
  • 17
    • 0022642527 scopus 로고
    • Differential responsiveness of myc- and ras-transfected cells to growth factors: Selective stimulation of myc-transfected cells by epidermal srowth factor
    • Stern DF, Roberts AB, Roche NS. Sporn MB and Weinberg RA: Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal srowth factor. Mol Cell Biol 6: 870-877, 1986.
    • (1986) Mol Cell Biol , vol.6 , pp. 870-877
    • Stern, D.F.1    Roberts, A.B.2    Roche, N.S.3    Sporn, M.B.4    Weinberg, R.A.5
  • 18
    • 0021140954 scopus 로고
    • Epidermal growth factor binding by breast tumor biopsies and relationship to estrogen receptor and progestin receptor
    • Fitzpatrick SL, Brightwell J, Wittliff JL, Barrows GH and Schultz GS: Epidermal growth factor binding by breast tumor biopsies and relationship to estrogen receptor and progestin receptor. Cancer Res 44: 3448-3453, 1984.
    • (1984) Cancer Res , vol.44 , pp. 3448-3453
    • Fitzpatrick, S.L.1    Brightwell, J.2    Wittliff, J.L.3    Barrows, G.H.4    Schultz, G.S.5
  • 19
    • 0025240329 scopus 로고
    • Radiolabeling of proteins
    • Parker CW: Radiolabeling of proteins. Methods Enzymol 182: 721-737, 1990.
    • (1990) Methods Enzymol , vol.182 , pp. 721-737
    • Parker, C.W.1
  • 20
    • 0031205544 scopus 로고    scopus 로고
    • Association between p53 mutation and clinicopathological features of non-small cell lung cancer
    • Shao GG, Ogura T, Sekine I, Yokozaki M, Esumi H, Kodama T and Nagai K: Association between p53 mutation and clinicopathological features of non-small cell lung cancer. Jpn J Clin Oncol 27: 211-215, 1997.
    • (1997) Jpn J Clin Oncol , vol.27 , pp. 211-215
    • Shao, G.G.1    Ogura, T.2    Sekine, I.3    Yokozaki, M.4    Esumi, H.5    Kodama, T.6    Nagai, K.7
  • 21
    • 0027724071 scopus 로고
    • Amplification and point-mutation alterations of oncogenes in patients with cervical cancer-associated human papillomavirus
    • Kinoshita M, Katsuragi K, Shin S and Aono T: Amplification and point-mutation alterations of oncogenes in patients with cervical cancer-associated human papillomavirus. Biomed Res 14: 403-410, 1993.
    • (1993) Biomed Res , vol.14 , pp. 403-410
    • Kinoshita, M.1    Katsuragi, K.2    Shin, S.3    Aono, T.4
  • 23
    • 0024510886 scopus 로고
    • Characterization of epidermal growth factor receptor in primary human non-small cell lung cancer
    • Veale D, Kerr N, Gibson GJ and Haris AL: Characterization of epidermal growth factor receptor in primary human non-small cell lung cancer. Cancer Res 49: 1313-1317, 1989.
    • (1989) Cancer Res , vol.49 , pp. 1313-1317
    • Veale, D.1    Kerr, N.2    Gibson, G.J.3    Haris, A.L.4
  • 24
    • 0028937815 scopus 로고
    • Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype
    • Fontanini G, Vignati S, Bigini D, Mussi A, Lucchi H, Angeletti CA, Pingitore R, Pepe S, Basolo F and Bevilacqua G: Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype. Eur J Cancer 31 A: 178-183, 1995.
    • (1995) Eur J Cancer , vol.31 A , pp. 178-183
    • Fontanini, G.1    Vignati, S.2    Bigini, D.3    Mussi, A.4    Lucchi, H.5    Angeletti, C.A.6    Pingitore, R.7    Pepe, S.8    Basolo, F.9    Bevilacqua, G.10
  • 26
    • 0021799835 scopus 로고
    • Difference in human skin between epidermal growth factor receptor distribution detected by EGF binding and monoclonal antibody recognition
    • Green MR and Couchman JR: Difference in human skin between epidermal growth factor receptor distribution detected by EGF binding and monoclonal antibody recognition. J Invest Dermatol 85: 239-245, 1985.
    • (1985) J Invest Dermatol , vol.85 , pp. 239-245
    • Green, M.R.1    Couchman, J.R.2
  • 27
    • 0026654238 scopus 로고
    • Ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis
    • Sugio K, Ishida T, Yokoyama H, Inoue T, Sugimachi K and Sasazuki T: Ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res 52: 2903-2906, 1992.
    • (1992) Cancer Res , vol.52 , pp. 2903-2906
    • Sugio, K.1    Ishida, T.2    Yokoyama, H.3    Inoue, T.4    Sugimachi, K.5    Sasazuki, T.6
  • 28
    • 0002466673 scopus 로고    scopus 로고
    • The role of MYC, JUN and FOS oncogenes in human lung cancer
    • Pass HI, Mitchell JB, Johnson DH and Turrisi AT (eds.) Lippincott-Raven Publishers, Philadelphia
    • Johnson BE: The role of MYC, JUN and FOS oncogenes in human lung cancer. In: Lung Cancer: Principles & Practice. Pass HI, Mitchell JB, Johnson DH and Turrisi AT (eds.) Lippincott-Raven Publishers, Philadelphia, pp83-98, 1996.
    • (1996) Lung Cancer: Principles & Practice , pp. 83-98
    • Johnson, B.E.1
  • 29
    • 0030899807 scopus 로고    scopus 로고
    • Tyrosine phosphorylation sites at amino acids 239 and 240 of She are involved in epidermal growth factor-induced mitogenic signaling that is distinct from ras/mitogen-activated protein kinase activation
    • Gotoh N, Toyoda M and Shibuya M: Tyrosine phosphorylation sites at amino acids 239 and 240 of She are involved in epidermal growth factor-induced mitogenic signaling that is distinct from ras/mitogen-activated protein kinase activation. Mol Cell Biol 17: 1824-1831, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 1824-1831
    • Gotoh, N.1    Toyoda, M.2    Shibuya, M.3
  • 30
    • 0025195107 scopus 로고
    • Accumulation of p21 ras GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity
    • Satoh T, Endo M, Nakafuku M, Akiyama T. Yamamoto T and Kaziro Y: Accumulation of p21 ras GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity. Proc Natl Acad Sci USA 87: 7926-7929, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7926-7929
    • Satoh, T.1    Endo, M.2    Nakafuku, M.3    Akiyama, T.4    Yamamoto, T.5    Kaziro, Y.6
  • 31
    • 0023140028 scopus 로고
    • Loss of growth responsiveness to epidermal growth factor and enhanced production of alpha-transforming growth factors in ras-transformed mouse mammary epithelial cells
    • Salomon DS, Perroteau I, Kidwell WR, Tam J and Derynck R: Loss of growth responsiveness to epidermal growth factor and enhanced production of alpha-transforming growth factors in ras-transformed mouse mammary epithelial cells. J Cell Physiol 130: 397-409, 1987.
    • (1987) J Cell Physiol , vol.130 , pp. 397-409
    • Salomon, D.S.1    Perroteau, I.2    Kidwell, W.R.3    Tam, J.4    Derynck, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.