Differential antagonism by conotoxin ρ-TIA of contractions mediated by distinct α1-adrenoceptor subtypes in rat vas deferens, spleen and aorta

European Journal of Pharmacology

Volumn 508, Issue 1-3, 2005, Pages 183-192

  Lima, Vanessa ^a   Mueller, André ^a   Kamikihara, Susana Y ^a   Raymundi, Vanessa ^a   Alewood, Dianne ^b   Lewis, Richard J ^b   Chen, Zhongjian ^c   Minneman, Kenneth P ^c   Pupo, André S ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b Xenome Ltd   (Australia)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1 adrenoceptor; Aorta; Conotoxin TIA; Spleen; Vas deferens

Indexed keywords

2 [2 (4 HYDROXYPHENYL)ETHYLAMINOMETHYL]TETRALONE; 5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CONOTOXIN; IODINE 125; NORADRENALIN; PHENOXYBENZAMINE; PRAZOSIN;

ANIMAL EXPERIMENT; AORTA; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFECT; DRUG ISOLATION; DRUG POTENCY; HUMAN; HUMAN CELL; IC 50; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; RAT; SNAIL; SPLEEN; STATISTICAL SIGNIFICANCE; VAS DEFERENS;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AORTA, THORACIC; BINDING, COMPETITIVE; CELL LINE; CELL MEMBRANE; CONOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IODINE RADIOISOTOPES; MALE; MUSCLE CONTRACTION; NOREPINEPHRINE; PIPERAZINES; POTASSIUM CHLORIDE; PRAZOSIN; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; SPLEEN; TETRALONES; VAS DEFERENS;

EID: 12844282068     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.12.011     Document Type: Article

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