Hepatitis a virus proteinase 3C binding to viral RNA: Correlation with substrate binding and enzyme dimerization

Biochemical Journal

Volumn 385, Issue 2, 2005, Pages 363-370

  Peters, Hannelore ^a   Kusov, Yuri Y ^a   Meyer, Sonja ^a   Benie, Andrew J ^a   Bäuml, Englbert ^a   Wolff, Maike ^a   Rademacher, Christoph ^a   Peters, Thomas ^a   Gauss Müller, Verena ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Dimerization; Hepatitis A virus; NMR; Proteinase 3C; RNA binding; Surface plasmon resonance (SPR)

Indexed keywords

DATA ACQUISITION; DIMERS; GENES; PROTEINS; RNA; SURFACE PLASMON RESONANCE; VIRUSES;

GENOME REPLICATION; HEPATITIS A VIRUS (HAV); PROTEASE ACTIVITY; PROTEOLYTIC ACTIVITY;

ENZYME KINETICS;

PEPTIDE; PROTEINASE; PROTEINASE 3C; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CORRELATION ANALYSIS; DIMERIZATION; DISSOCIATION CONSTANT; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME MODIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE REPLICATION; HEPATITIS A VIRUS; LIFE CYCLE; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN RNA BINDING; PROTEIN SECRETION; RNA SYNTHESIS; SURFACE PLASMON RESONANCE; VIROGENESIS; VIRUS GENOME; VIRUS REPLICATION;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYSTEINE ENDOPEPTIDASES; DIMERIZATION; ENZYMES, IMMOBILIZED; HEPATITIS A VIRUS; HUMANS; HYDROLYSIS; LIVER NEOPLASMS; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECOMBINANT PROTEINS; RNA, VIRAL; SUBSTRATE SPECIFICITY;

HEPATITIS A VIRUS; RNA VIRUSES;

EID: 12844264099     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041153     Document Type: Article

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