Contribution of persistent sodium currents to spike-frequency adaptation in rat hypoglossal motoneurons

Journal of Neurophysiology

Volumn 93, Issue 2, 2005, Pages 1035-1041

  Zeng, Jinsong ^a   Powers, Randall K ^a   Newkirk, Gregory ^a   Yonkers, Marc ^a   Binder, Marc D ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYTOIN;

ACTION POTENTIAL; ANALYSIS OF VARIANCE; ANIMAL CELL; ARTICLE; BRAIN STEM; DATA ANALYSIS; HYPOGLOSSAL NERVE; MEMBRANE CHANNEL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SODIUM CURRENT; SPIKE; SPIKE FREQUENCY ADAPTATION; SPINAL CORD MOTONEURON; VOLTAGE CLAMP;

ACTION POTENTIALS; ADAPTATION, PHYSIOLOGICAL; ANIMALS; HYPOGLOSSAL NERVE; MOTOR NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 12544257551     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00831.2004     Document Type: Article

References (36)

1. Baldissera F, Campadelli P, and Piccinelli L. The dynamic response of cat gastrocnemius motor units investigated by ramp-current injection into their motoneurones. J Physiol 387: 317-330, 1987.
2. Baldissera F and Gustafsson B. After hyperpolarization time course in lumbar motoneurones of the cat. Acta Physiol Scand 91: 512-527, 1974.
3. Baldissera F, Gustafsson B, and Parmiggiani F. Saturating summation of the after hyperpolarization conductance in spinal motoneurones: a mechanism for 'secondary range' repetitive firing. Brain Res 146: 69-82, 1978.
4. Bennett DJ, Hultborn H, Fedirchuk B, and Gorassini M. Short-term plasticity in hindlimb motoneurons of decerebrate cats. J Neurophysiol 80: 2038-2045, 1998.
5. Bigland-Ritchie B, Johansson K, Lippold OC, Smith S, and Woods JJ. Changes in motoneurone firing rates during sustained maximal voluntary contractions. J Physiol 340: 335-346, 1983a.
6. Bigland-Ritchie B, Johansson R, Lippold OC, and Woods JJ. Contractile speed and EMG changes during fatigue of sustained maximal voluntary contractions. J Neurophysiol 50: 313-324, 1983b.
7. Carlin KP, Jiang Z, and Brownstone RM. Characterization of calcium currents in functionally mature mouse spinal motoneurons. Eur J Neurosci 12: 1624-1634, 2000.
8. de Jongh HR and Kernell D. Limits of usefulness of electrophysiological methods for estimating dendritic length in neurones. J Neurosci Methods 6: 129-138, 1982.
9. + current and slow cumulative spike adaptation in mouse and guinea-pig neocortical neurones in slices. J Physiol 493: 83-97, 1996.
10. Granit R, Kernell D, and Shortess GK. Quantitative aspects of repetitive firing of mammalian motoneurones, caused by injected currents. J Physiol 168: 911-931, 1963.
11. Hsiao CF, DelNegro CA, Trueblood PR, and Chandler SH. Ionic basis for serotonin-induced bistable membrane properties in guinea pig trigeminal motoneurons. J Neurophysiol 79: 2847-2856, 1998.
12. Kernell D. The adaptation and the relation between discharge frequency and current strength of cat lumbosacral motoneurones stimulated by long-lasting injected currents. Acta Physiol Scand 65: 65-73, 1965.
13. Kernell D. The repetitive impulse discharge of a simple neurone model compared to that of spinal motoneurones. Brain Res 11: 685-687, 1968.
14. Kernell D and Monster AW. Motoneuron properties and motor fatigue. Exp Brain Res 46: 197-204, 1982.
15. Kuo C-C and Bean BP. Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons. Mol Pharm 46: 716-725, 1994.
16. + current. J Pharmacol Exp Ther 284: 228-237, 1998.
17. Lee RH and Heckman CJ. Bistability in spinal motoneurons in vivo: systematic variations in persistent inward currents. J Neurophysiol 80: 583-593, 1998a.
18. Lee RH and Heckman CJ. Bistability in spinal motoneurons in vivo: systematic variations in rhythmic firing patterns. J Neurophysiol 80: 572-582, 1998b.
19. Lee RH and Heckman CJ. Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing. J Neurophysiol 85: 472-475, 2001.
20. Lee RH and Heckman CJ. Adjustable amplification of synaptic input in the dendrites of spinal motoneurons In vivo. J Neurosci 20: 6734-6740, 2000.
21. Madison DV and Nicoll RA. Control of the repetitive discharge of rat CA1 pyramidal neurones in vitro. J Physiol 354: 319-331, 1984.
22. Musick JR. Mechanisms Underlying Spike-Frequency Adaptation in Hypoglossal Motoneurons, PhD dissertation. Seattle, WA: University of Washington, 1999.
23. Nunez-Abades PA, Spielmann JM, Barrionuevo G, and Cameron WE. In vitro electrophysiology of developing genioglossal motoneurons in the rat. J Neurophysiol 70: 1401-1411, 1993.
24. Poliakov AV, Powers RK, Sawczuk A, and Binder MD. Effects of background noise on the response of rat and cat motoneurones to excitatory current transients. J Physiol 495: 143-157, 1996.
25. Powers RK and Binder MB. Input-output functions of mammalian motoneurons. Rev Physiol Biochem Pharmacol 143: 137-263, 2001.
26. Powers RK and Binder MD. Persistent sodium and calcium currents in rat hypoglossalal motoneurons. J Neurophysiol 89: 615-624, 2003.
27. Powers RK, Sawczuk A, Musick JR, and Binder MD. Multiple mechanisms of spike-frequency adaptation in motoneurones. J Physiol 93: 101-114, 1999.
28. Sawczuk A. Adaptation in Sustained Motoneuron Discharge, PhD dissertation. Seattle, WA: University of Washington, 1993.
29. Sawczuk A, Powers RK, and Binder MD. Intrinsic properties of motoneurons: implications for muscle fatigue. In: Neural and Neuromuscular Aspects of Muscle Fatigue, edited by Gandevia S, Enoka R, McComas A, Stuart D, and Thomas C. New York: Plenum, 1995a, p. 123-134.
30. Sawczuk A, Powers RK, and Binder MD. Spike frequency adaptation studied in hypoglossal motoneurons of the rat. J Neurophysiol 73: 1799-1810, 1995b.
31. Sawczuk A, Powers RK, and Binder MD. Contribution of outward currents to spike-frequency adaptation in hypoglossal motoneurons of the rat. J Neurophysiol 78: 2246-2253, 1997.
32. Schwindt PC, Spain WJ, and Crill WE. Long-lasting reduction of excitability by a sodium-dependent potassium current in cat neocortical neurons. J Neurophysiol 61: 233-244, 1989.
33. Schwindt PC, Spain WJ, Foehring RC, Chubb MC, and Crill WE. Slow conductances in neurons from cat sensorimotor cortex in vitro and their role in slow excitability changes. J Neurophysiol 59: 450-467, 1988.
34. Spielmann JM, Laouris Y, Nordstrom MA, Robinson GA, Reinking RM, and Stuart DG. Adaptation of cat motoneurons to sustained and intermittent extracellular activation. J Physiol) 464: 75-120, 1993.
35. Storm JF. Potassium currents in hippocampal pyramidal cells. Prog Brain Res 83: 161-187, 1990.
36. Svirskis G and Hounsgaard J. Depolarization-induced facilitation of a plateau-generating current in ventral horn neurons in the turtle spinal cord. J Neurophysiol 78: 1740-1742, 1997.