Regulation of cytosolic pH and lactic acid release in mesangial cells overexpressing GLUT1

Kidney International

Volumn 64, Issue 4, 2003, Pages 1338-1347

  Lang, Karl S ^b   Mueller, Matthias M ^b   Tanneur, Valerie ^b   Wallisch, Sabine ^b   Fedorenko, Olga ^b   Palmada, Monica ^b   Lang, Florian ^a   Bröer, Stefan ^b   Heilig, Charles W ^b   Schleicher, Erwin ^b   Weigert, Cora ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MENTAL HEALTH RESEARCH INSTITUTE   (Russian Federation)

Author keywords

Acidosis; Glycolysis; H+ ATPase; LacZ; MCT; NHE

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; BETA GALACTOSIDASE; CHLOROMERCURIBENZENESULFONIC ACID; GLUCOSE; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER 1; LACTIC ACID; O METHYLGLUCOSE; PHLORETIN; PROTEIN INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ALKALINIZATION; ANIMAL CELL; ARTICLE; CELL TYPE; CONTROLLED STUDY; GENETIC TRANSFECTION; GLUCOSE TRANSPORT; GLYCOLYSIS; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 12444332628     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00213.x     Document Type: Article

References (35)

1. BROWN PD, ELLIOTT AC, LAU KR: Indirect evidence for the presence of non-specific anion channels in rabbit mandibular salivary gland acinar cells. J Physiol 414:415-431, 1989
2. NILIUS B, PRENEN J, DROOGMANS G: Modulation of volume-regulated anion channels by extra- and intracellular pH. Pflugers Arch 436:742-748, 1998
3. ROY G: Amino acid current through anion channels in cultured human glial cells. J Membr Biol 147:35-44, 1995
4. BROER S, SCHNEIDER HP, BROER A, et al: Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Biochem J 333:167-174, 1998
5. CARPENTER L, HALESTRAP AP: The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF. Biochem J 304:751-760, 1994
6. DIMMER KS, FRIEDRICH B, LANG F, et al: The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 350:219-227, 2000
7. JACKSON VN, HALESTRAP AP: The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2′,7′-bis(carboxyethyl)-5(6)-carboxyfluorescein. J Biol Chem 271:861-868, 1996
8. + transporter isoforms MCT1 and MCT4 in human skeletal muscle. Am J Physiol 276:E843-E848, 1999
9. HALESTRAP AP, PRICE NT: The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation. Biochem J 343:281-299, 1999
10. BROWNLEE M: Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820, 2001
11. MOGYOROSI A, ZIYADEH FN: GLUT1 and TGF-beta: The link between hyperglycaemia and diabetic nephropathy. Nephrol Dial Transplant 14:2827-2829, 1999
12. HEILIG CW, LIU Y, ENGLAND RL, et al: D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: Implications for diabetic nephropathy. Diabetes 46:1030-1039, 1997
13. HEILIG CW, CONCEPCION LA, RISER BL, et al: Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype. J Clin Invest 96:1802-1814, 1995
14. -. Am J Physiol 255:C844-C856, 1988
15. BOYARSKY G, GANZ MB, STERZEL RB, BORON WF: pH regulation in single glomerular mesangial cells. II. Na+-dependent and -independent Cl(-)-. Am J Physiol 255:C857-C869, 1988
16. RITTER M, WÖLL E: Modification of cellular ion transport by the Ha-ras oncogene: Steps towards malignant transformation. Cell Physiol Biochem 6:245-270, 1996
17. - by stimulating three acid-base transport systems. Nature 337:648-651, 1989
18. ROOS A, BORON WF: Intracellular pH. Physiol Rev 61:296-434, 1981
19. DROSE S, ALTENDORF K: Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases. J Exp Biol 200:1-8, 1997
20. ABRAHAMSE SL, VIS A, BINDELS RJ, VAN OS CH: Regulation of intracellular pH in crypt cells from rabbit distal colon. Am J Physiol 267:G409-G415, 1994
21. DENNIS SC, GEVERS W, OPIE LH: Protons in ischemia: Where do they come from; where do they go to? J Mol Cell Cardiol 23:1077-1086, 1991
22. GEVERS W: Generation of protons by metabolic processes in heart cells. J Mol Cell Cardiol 9:867-874, 1977
23. NOEL J, POUYSSEGUR J: Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms. Am J Physiol 268:C283-C296, 1995
24. PUTNEY LK, DENKER SP, BARBER DL: The changing face of the Na+/H+ exchanger, NHE1: Structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol 42:527-552, 2002
25. BIDANI A, HEMING TA: Kinetic analysis of cytosolic pH regulation in alveolar macrophages: V-ATPase-mediated responses to a weak acid. Am J Physiol 269:L20-L29, 1995
26. DUNBAR LA, CAPLAN MJ: The cell biology of ion pumps: sorting and regulation. Eur J Cell Biol 79:557-563, 2000
27. OKAMOTO CT, FORTE JG: Vesicular trafficking machinery, the actin cytoskeleton, and H +-K+-ATPase recycling in the gastric parietal cell. J Physiol 532:287-296, 2001
28. WEIGERT C, BRODBECK K, BROSIUS FC, III, et al: Evidence for a novel TGF-beta1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters. Diabetes 52:527-535, 2003
29. MALY K, STRESE K, KAMPFER S, et al: Critical role of protein kinase C alpha and calcium in growth factor induced activation of the Na(+)/H(+) exchanger NHE1. FEBS Lett 521:205-210, 2002
30. PEDERSON SF, VARMING C, CHRISTENSEN ST, HOFFMAN EK: Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells. J Membr Biol 189:67-81, 2002
31. WEINMAN EJ, DUBINSKY W, SHENOLIKAR S: Regulation of the renal Na+-H+ exchanger by protein phosphorylation. Kidney Int 36:519-525, 1989
32. GANZ MB, HAWKINS K, REILLY RF: High glucose induces the activity and expression of Na(+)/H(+) exchange in glomerular mesangial cells. Am J Physiol Renal Physiol 278:F91-F96, 2000
33. DOMINGUEZ JH, SOLEIMANI M, BATIUK T: Studies of renal injury IV: The GLUT1 gene protects renal cells from cyclosporine A toxicity. Kidney Int 62:127-136, 2002
34. JENNINGS RB, REIMER KA: The cell biology of acute myocardial ischemia. Annu Rev Med 42:225-246, 1991
35. BROER S, BROER A, SCNEIDER HP, et al: Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem J 341:529-535, 1999