Development and applications of a β-catenin oligonucleotide microarray: β-catenin mutations are dominantly found in the proximal colon cancers with microsatellite instability

Clinical Cancer Research

Volumn 9, Issue 8, 2003, Pages 2920-2925

  Kim, Il Jin ^b   Kang, Hio Chung ^b   Park, Jae Hyun ^b   Shin, Yong ^b   Ku, Ja Lok ^b   Lim, Seok Byung ^c   Park, So Yeon ^a   Jung, Seung Yong ^a   Kim, Hark Kyun ^a   Park, Jae Gahb ^a,b,c  

^a National Cancer Center   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; OLIGONUCLEOTIDE;

ARTICLE; CANCER CELL CULTURE; COLON CANCER; COLORECTAL CANCER; DNA MICROARRAY; DNA POLYMORPHISM; GENE DELETION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ADULT; BETA CATENIN; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; DNA MUTATIONAL ANALYSIS; DNA SEQUENCE, UNSTABLE; GENE DELETION; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; MUTATION, MISSENSE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANS-ACTIVATORS;

EID: 12444265752     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Abraham, S. C., Nobukawa, B., Giardiello, F. M., Hamilton, S. R., and Wu, T. T. Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the β-catenin gene. Am. J. Pathol., 158: 1005-1010, 2001.
2. Abraham, S. C., Montgomery, E. A., Giardiello, F. M., and Wu, T. T. Frequent β-catenin mutations in juvenile nasopharyngeal angiofibromas. Am. J. Pathol., 158: 1073-1078, 2001.
3. Saegusa, M., and Okayasu, I. Frequent nuclear β-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation. J. Pathol., 194: 59-67, 2001.
4. Nilbert, M., and Rambech, E. β-Catenin activation through mutation is rare in rectal cancer. Cancer Genet. Cytogenet., 128: 43-45, 2001.
5. Mirabelli-Primdahl, L., Gryfe, R., Kim, H., Millar, A., Luceri, C., Dale, D., Holowaty, E., Bapat, B., Gallinger, S., and Redston, M. β-Catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway. Cancer Res., 59: 3346-3351, 1999.
6. Devereux, T. R., Stern, M. C., Flake, G. P., Yu, M. C., Zhang, Z. Q., London, S. J., and Taylor, J. A. CTNNB1 mutations and β-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1. Mol. Carcinog., 31; 68-73, 2001.
7. Udatsu, Y., Kusafuka, T., Kuroda, S., Miao, J., and Okada, A. High frequency of β-catenin mutations in hepatoblastoma. Pediatr. Surg. Int., 17: 508-512, 2001.
8. Koch, A., Denkhaus, D., Albrecht, S., Leuschner, I., von Schweinitz, D., and Pietsch, T. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the β-catenin gene. Cancer Res., 59: 269-273, 1999.
9. de La Coste, A., Romagnolo, B., Billuart, P., Renard, C. A., Buendia, M. A., Soubrane, O., Fabre, M., Chelly, J., Beldjord, C., Kahn, A., and Perret, C. Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc. Natl. Acad. Sci. USA, 95: 8847-8851, 1998.
10. Shitoh, K., Furukawa, T., Kojima, M., Konishi, F., Miyaki, M., Tsukamoto, T., and Nagai, H. Frequent activation of the β-catenin-Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability. Genes Chromosomes Cancer, 30: 32-37, 2001.
11. Samowitz, W. S., Powers, M. D., Spirio, L. N., Nollet, F., van Roy, F., and Slattery, M. L. β-Catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas. Cancer Res., 59: 1442-1444, 1999.
12. Traverso, G., Shuber, A., Olsson, L., Levin, B., Johnson, C., Hamilton, S. R., Boynton, K., Kinzler, K. W., and Vogelstein, B. Detection of proximal colorectal cancers through analysis of faecal DNA. Lancet, 359: 403-404, 2002.
13. Ahlquist, D. A., Skoletsky, J. E., Boynton, K. A., Harrington, J. J., Mahoney, D. W., Pierceall, W. E., Thibodeau, S. N., and Shuber, A. P. Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel. Gastroenterology, 119: 1219-1227, 2000.
14. Dong, S. M., Traverso, G., Johnson, C., Geng, L., Favis, R., Boynton, K., Hibi, K., Goodman, S. N., D'Allessio, M., Paty, P., Hamilton, S. R., Sidransky, D., Barany, F., Levin, B., Shuber, A., Kinzler, K. W., Vogelstein, B., and Jen, J. Detecting colorectal cancer in stool with the use of multiple genetic targets. J. Natl. Cancer Inst., 93: 858-865, 2001.
15. Woo, D. K., Kim, H. S., Lee, H. S., Kang, Y. H., Yang, H. K., and Kim, W. H. Altered expression and mutation of β-catenin gene in gastric carcinomas and cell lines. Int. J. Cancer, 95: 108-113, 2001.
16. Kim, I. J., Kang, H. C., Park, J. H., Ku, J. L., Lee, J. S., Kwon, H. J., Yoon, K. A., Heo, S. C., Yang, H. Y., Cho, B. Y., Kim, S. Y., Oh, S. K., Youn, Y. K., Park, D. J., Lee, M. S., Lee, K. W., and Park, J. G. RET oligonucleotide microarray for the detection of RET mutations in multiple endocrine neoplasia type 2 syndromes. Clin. Cancer Res., 8: 457-463, 2002.
17. Kim, I. J., Ku, J. L., Yoon, K. A., Heo, S. C., Jeong, S. Y., Choi, H. S., Hong, K. H., Yang, S. K., and Park, J. G. Germline mutations of the dpc4 gene in Korean juvenile polyposis patients. Int. J. Cancer, 86: 529-532, 2000.
18. Wagner, T., Stoppa-Lyonnet, D., Fleischmann, E., Muhr, D., Pages, S., Sandberg, T., Caux, V., Moeslinger, R., Langbauer, G., Borg, A., and Oefner, P. Denaturing high-performance liquid chromatography detects reliably BRCA1 and BRCA2 mutations. Genomics, 62: 369-376, 1999.
19. Won, Y. J., Park, K. J., Kwon, H. J., Lee, J. H., Kim, J. H., Kim, Y. J., Chun, S. H., Han, H. J., and Park, J. G. Germline mutations of the APC gene in Korean familial adenomatous polyposis patients. J. Hum. Genet., 44: 103-108, 1999.
20. Samowitz, W. S., Holden, J. A., Curtin, K., Edwards, S. L., Walker, A. R., Lin, H. A., Robertson, M. A., Nichols, M. F., Gruenthal, K. M., Lynch, B. J., Leppert, M. F., and Slattery, M. L. Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. Am. J. Pathol., 158: 1517-1524, 2001.
21. Ilyas, M., Tomlinson, I. P., Rowan, A., Pignatelli, M., and Bodmer, W. F. β-Catenin mutations in cell lines established from human colorectal cancers. Proc. Natl. Acad. Sci. USA, 94: 10330-10334, 1997.
22. Muller, O., Nimmrich, I., Finke, U., Friedl, W., and Hoffmann, I. A β-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of β-catenin germline mutations in FAP patients. Genes Chromosomes Cancer, 22: 37-41, 1998.
23. Tong, J. H., To, K. F., Ng, E. K., Lau, J. Y., Lee, T. L., Lo, K. W., Leung, W. K., Tang, N. L., Chan, F. K., Sung, J. J., and Chung, S. C. Somatic β-catenin mutation in gastric carcinoma-an infrequent event that is not specific for microsatellite instability. Cancer Lett., 163: 125-130, 2001.
24. Hoang, J. M., Cottu, P. H., Thuille, B., Salmon, R. J., Thomas, G., and Hamelin, R. BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res., 57: 300-303, 1997.
25. Sparks, A. B., Morin, P. J., Vogelstein, B., and Kinzler, K. W. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res., 58: 1130-1134, 1998.
26. Oh, J. H., Ku, J. L., Yoon, K. A., Kwon, H. J., Kim, W. H., Park, H. S., Yeo, K. S., Song. S. Y., Chung, J. K., and Park, J. G. Establishment and characterization of 12 human colorectal-carcinoma cell lines. Int. J. Cancer, 81: 902-910, 1999.