Cholesterol feeding of mice expressing cholesterol 7α-hydroxylase increases bile acid pool size despite decreased enzyme activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 7, 2004, Pages 1846-1851

  Tiemann, Michaela ^a   Han, Zhihua ^a   Soccio, Raymond ^a   Bollineni, Jaya ^b   Shefer, Sarah ^b   Sehayek, Ephraim ^a   Breslow, Jan L ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHOLESTEROL; CHOLESTEROL 27 HYDROXYLASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYTOCHROME P 450C27/25; CYTOCHROME P-450C27/25; MESSENGER RNA; OXYGENASE; STEROID MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL EXPERIMENT; ARTICLE; BILE ACID BLOOD LEVEL; BILE ACID SYNTHESIS; BILE FLOW; BLOOD; CHEMISTRY; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CHOLESTEROL INTAKE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FECES; FEMALE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HETEROZYGOTE; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLESTEROL, DIETARY; CYTOCHROME P-450 CYP27A1; FECES; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HETEROZYGOTE; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RNA, MESSENGER; STEROID HYDROXYLASES;

ANIMALIA; MUS MUSCULUS;

EID: 1242342009     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308426100     Document Type: Article

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