A 21-amino acid peptide from the cysteine cluster II of the family D DNA polymerase from Pyrococcus horikoshii stimulates its nuclease activity which is Mre11-like and prefers manganese ion as the cofactor

Nucleic Acids Research

Volumn 32, Issue 1, 2004, Pages 158-168

  Shen, Yulong ^a   Tang, Xiao Feng ^a   Yokoyama, Hideshi ^a   Matsui, Eriko ^a   Matsui, Ikuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; DEOXYRIBONUCLEASE; DNA POLYMERASE; EXONUCLEASE; MAGNESIUM; MANGANESE; METAL ION; MRE11 PROTEIN; NUCLEASE; PROTEIN SUBUNIT; ZINC FINGER PROTEIN; ARCHAEAL PROTEIN; DNA DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASE; MRE11 PROTEIN, ARCHAEAL; PEPTIDE FRAGMENT; SINGLE STRANDED DNA;

ARTICLE; CATALYSIS; CLUSTER ANALYSIS; COMPUTER ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PYROCOCCUS; PYROCOCCUS HORIKOSHII; SITE DIRECTED MUTAGENESIS; ZINC FINGER MOTIF; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COENZYME; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYMOLOGY; GENE DELETION; GENETICS; METABOLISM; MOLECULAR GENETICS;

BACTERIA (MICROORGANISMS); PYROCOCCUS; PYROCOCCUS HORIKOSHII;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; COENZYMES; CYSTEINE; DNA, SINGLE-STRANDED; DNA-DIRECTED DNA POLYMERASE; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN SUBUNITS; PYROCOCCUS HORIKOSHII; SEQUENCE DELETION;

EID: 1242331846     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh153     Document Type: Article

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