Mutational and pH studies of the 3' → 5' exonuclease activity of bacteriophage T4 DNA polymerase

Journal of Biological Chemistry

Volumn 274, Issue 35, 1999, Pages 25151-25158

  Elisseeva, Elena ^a,b   Mandal, Subhrangsu S ^b   Reha Krantz, Linda J ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; DNA POLYMERASE; EXONUCLEASE; GLUTAMINE; HYDROXIDE; LYSINE; METAL ION; TYROSINE; WATER;

ARTICLE; BACTERIOPHAGE T4; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROLYSIS; MUTATION; NUCLEIC ACID BASE SUBSTITUTION; PH; PRIORITY JOURNAL;

BINDING SITES; DNA POLYMERASE I; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; EXONUCLEASES; HYDROGEN-ION CONCENTRATION; METALS; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; POLY T; PROTEIN BINDING; PROTEIN CONFORMATION; RNA, CATALYTIC; VIRAL PROTEINS; WATER;

EID: 0033609776     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.35.25151     Document Type: Article

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