Dialkylaminoacetonitrile Derivatives as Amide Synthons. A One-Pot Preparation of Heteroaryl Amides via a Strategy of Sequential SNAr Substitution and Oxidation

Journal of Organic Chemistry

Volumn 69, Issue 4, 2004, Pages 1360-1363

  Zhang, Zhongxing ^a   Yin, Zhiwei ^a   Kadow, John F ^a   Meanwell, Nicholas A ^a   Wang, Tao ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; NICKEL COMPOUNDS; OXIDATION; SUBSTITUTION REACTIONS;

BASE-MEDIATED COUPLINGS; OXIDANTS;

ACETONITRILE;

2,3 DICHLOROPYRAZINE; ACETONITRILE DERIVATIVE; AMINOACETONITRILE; AROMATIC AMIDE; CYANOHYDRIN; DELAVIRDINE; N,N DIETHYLACETONITRILE; NICKEL; OXIDIZING AGENT; PYRAZINE DERIVATIVE; RILMAZAFONE; UNCLASSIFIED DRUG; WATER;

ARTICLE; DRUG SYNTHESIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; REACTION ANALYSIS; SUBSTITUTION REACTION;

AMIDES; AMINOACETONITRILE; HETEROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION;

EID: 1242307319     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo030233j     Document Type: Article

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