Effects of prednisolone on glomerular signal transduction cascades in experimental glomerulonephritis

Journal of the American Society of Nephrology

Volumn 9, Issue 8, 1998, Pages 1367-1376

  Seto, Masumi ^a   Kim, Shokei ^a   Yoshifusa, Hiroto ^b   Nakamura, Yutaka ^b   Masuda, Tatsunori ^b   Hamaguchi, Akinori ^a   Yamanaka, Shinya ^a   Iwao, Hiroshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NIPPON SHINYAKU CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PREDNISOLONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DRUG EFFECT; ENZYME INHIBITION; GLOMERULONEPHRITIS; GLOMERULUS FILTRATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0031879198     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Border WA, Okuda S, Languino LR, Sporn MB, Ruoslahti E: Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1. Nature 346: 371-374, 1990
2. Akagi Y, Isaka Y, Arai M, Kaneko T, Takenaka M, Moriyama T, Kaneda Y, Ando A, Orita Y, Kamada T, Ueda N, Imai E: Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int 50: 148-155, 1996
3. Border WA, Noble NA: Cytokines in kidney disease: The role of transforming growth factor. Am J Kidney Dis 22: 105-113, 1993
4. Sterzel RB, Luft FC, Mrax M: Cytokines and mesangial cells. Kidney Int 43: S26-S31, 1993
5. Floege F, Eng E, Young BA, Johnson RJ: Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo. Kidney Int 43: S47-S54, 1993
6. Couser WG, Johnson RJ: Mechanisms of progressive renal disease in glomerulonephritis. Am J Kidney Dis 23: 193-198, 1994
7. Kim SJ, Angel P, Lafyatis R, Hattori K, Kim KY, Sporn MB, Karin M, Roberts AB: Autoinduction of transforming growth factorB1 is mediated by the AP-1 complex. Mol Cell Biol 10: 1492-1497, 1990
8. Lee ME, Dhadly MS, Temizer DH, Clifford JA, Yoshizumi M, Quertermous T: Regulation of endothelin-1 gene expression by fos and jun. J Biol Chem 266: 19034-19039, 1991
9. Akira S, Kishimoto T: IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev 127: 25-50, 1992
10. Katai H, Stephenson JD, Simkevich CP, Thompson JP, Raghow R: An AP-1-like motif in the first intron of human proα1(I) collagen gene is a critical determinant of its transcriptional activity. Mol Cell Biochem 118: 119-129, 1992
11. Baeuerle PA, Henkel T: Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12: 141-179, 1994
12. Sen R, Baltimore D: Inducibility of kappa immunoglobulin enhancer-binding protein NF-kappa B by a posttranslational mechanism. Cell 47: 921-928, 1986
13. Sen R, Baltimore D: In vitro transcription of immunoglobulin genes in a B-cell extract: Effects of enhancer and promoter sequences. Mol Cell Biol 7: 1989-1994, 1987
14. Koning H, Ponta H, Rahmsdorf U, Herrlich H: Interference between pathway-specific transcription factors: Glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J 11: 2241-2246, 1992
15. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin A Jr: Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270: 283-286, 1995
16. Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin A Jr: Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol Cell Biol 15: 943-953, 1995
17. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270: 286-290, 1995
18. Edwards DR: Cell signalling and the control of gene transcription. Trends Pharmacol Sci 15: 239-244, 1994
19. Karin M: The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486, 1995
20. Joo-Hung P, Lee L: Overexpression of mitogen-activated protein kinase (ERK1) enhances T-cell cytokine gene expression: Role of AP-1, NF-AT, and NF-κB. Blood 82: 2470-2477, 1993
21. Yamamoto T, Wilson C: Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int 32: 514-525, 1987
22. Yagi K, Kim S, Wanibuchi H, Yamashita T, Yamamura Y, Iwao H: Characteristics of diabetes, blood pressure, and cardiac and renal complications in Otsuka Long-Evans Tokushima Fatty rats. Hypertension 29: 728-735, 1997
23. Schreiber E, Matthias P, Müller MM, Schaffner W: Rapid detection of octamer binding proteins with mini-extracts, prepared from a small number of cells. Nucleic Acids Res 17: 6419, 1989
24. Lee W, Mitchell P, Tjian R: Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49: 741-752, 1987
25. Kriwacki RW, Schultz SC, Steitz TA, Caradonna JP: Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp 1. Proc Nail Acad Sci USA 89: 9759-9763, 1992
26. Wagner BJ, Hayes TE, Hoban CJ, Cochran BH: The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J 9: 4477-4484, 1990
27. Hamaguchi A, Kim S, Yano S, Yamanaka S, Iwao H: Activation of glomerular mitogen-activated protein kinases in angiotensin II-mediated hypertension. J Am Soc Nephrol 9: 372-380, 1998
28. Kim S, Murakami T, Izumi Y, Yano M, Miura K, Yamanaka S, Iwao H: Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activities are continuously and differentially increased in aorta of hypertensive rats. Biochem Biophys Res Commun 236: 199-204, 1997
29. Laemmi UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
30. Hamaguchi A, Kim S, Wanibuchi H, Iwao H: Angiotensin II and calcium blockers prevent glomerular phenotypic changes in remnant kidney models. J Am Soc Nephrol 1: 687-693, 1996
31. Pesce MA, Strande CS: A new micromethod for determination of protein in cerebrospinal fluid and urine. Clin Chem 19: 1265-1267, 1973
32. Kim SJ, Glick A, Sporn MB, Roberts AB: Characterization of the promoter region of the human transforming growth factor-β1 gene. J Biol Chem 264: 402-408, 1989
33. Kaetzel DM, Maul RS, Liu B, Bonthron D, Fenstermaker RA, Coyne DW: Platelet-derived growth factor A-chain gene transcription is mediated by positive and negative regulatory regions in the promoter. Biochem J 15: 321-327, 1994
34. Bokemeyer D, Guglielmi KE, MucGinty A, Sorokin A, Lianos EA, Dunn MJ: Activation of extracellular signal-regulated kinase in proliferative glomerulonephritis in rats. J Clin Invest 100: 582-588, 1997
35. Minden A, Lin A, Smeal T, Derijard B, Cobb M, Davis R, Karin M: c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol 14: 6683-6688, 1994
36. Rider LG, Hirasawa N, Santini F, Beaven MA: Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells. J Immunol 157: 2374-2380, 1996
37. Chauhan D, Pandey P, Ogata A, Teoh G, Treon S, Urashima M, Kharbanda S, Anderson KC: Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism. Oncogene 15: 837-843, 1997
38. Kohase M, Henriksen-DiStefano D, Sehgal P, Vilcek J: Dexamethasone inhibits feedback regulation of the mitogenic activity of tumor necrosis factor, interleukin-1 and epidermal growth factor in human fibroblasts. J Cell Physiol 132: 271-278, 1987
39. Natori Y, Natori Y, Nishimura T, Yamabe H, Iyonaga K, Takeya M, Kawakami M: Production of monocyte chemoattractant protein-1 by cultured glomerular epithelial cells: Inhibition by dexamethasone. Exp Nephrol 5: 318-322, 1997
40. Wada T, Yokoyama H, Tomosugi N, Hisada Y, Ohta S, Naito T, Kobayashi K, Mukaida N, Matsushima K: Detection of urinary interleukin-8 in glomerular diseases. Kidney Int 46: 455-460, 1994
41. Taniguchi Y, Yorioka N, Oda H, Okushin S, Nishida Y, Yamakido M, Taguchi T: Glomerular localization of interleukin-6 suppressed by steroid mini-pulse therapy in an IgA nephropathy patient. Intern Med 34: 1181-1185, 1995
42. Bokemeyer D, Sorokin A, Dunn MJ: Multiple intracellular MAP kinase signaling cascades. Kidney Int 49: 1187-1198, 1996