WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8

Biochemical Journal

Volumn 377, Issue 3, 2004, Pages 553-560

  Nitsch, Roberto ^a   Di Palma, Tina ^a   Mascia, Anna ^a   Zannini, Mariastella ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Adaptor molecule; Pax protein; Protein protein interaction; Thyroid; Transcriptional regulation; WW domain binding protein (WBP)

Indexed keywords

BIOCHEMISTRY; CELLS; DNA; IMMUNOLOGY; TISSUE;

CELLULAR PHENOTYPES;

PROTEINS;

PROTEIN; PROTEIN WBP 2; THYROID TRANSCRIPTION FACTOR 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CONTROLLED STUDY; EUKARYOTE; GENE ACTIVATION; GENE IDENTIFICATION; GENETIC CODE; GENETIC TRANSCRIPTION; IMMUNOPRECIPITATION; MULTIGENE FAMILY; NONHUMAN; ORGANOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; THYROID GLAND;

ANIMALIA; EUKARYOTA;

EID: 1242292284     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj20031233     Document Type: Article

References (54)

1. Xu, L., Glass, C. K. and Rosenfeld, M. G. (1999) Coactivator and corepressor complexes in nuclear receptor function. Curr. Opin. Genet. Dev. 9, 140-147
2. Muchardt, C. and Yaniv, M. (1999) ATP-dependent chromatin remodelling: SWI/SNF and Co. are on the job. J. Mol. Biol. 293, 187-198
3. Orphanides, G., Lagrange, T. and Reinberg, D. (1996) The general transcription factors of RNA polymerase II. Genes Dev. 10, 2657-2683
4. Green, M. R. (2000) TBP-associated factors (TAFIIs): multiple, selective transcriptional mediators in common complexes. Trends Biochem. Sci. 25, 59-63
5. Pawson, T., Raina, M. and Nash, P. (2002) Interaction domains: from simple binding events to complex cellular behavior. FEBS Lett. 513, 2-10
6. Dikic, I. (2002) CIN85/CMS family of adaptor molecules. FEBS Lett. 529, 110-115
7. Dahl, E., Koseki, H. and Balling, R. (1997) Pax genes and organogenesis. Bioessays 19, 755-765
8. Noll, M. (1993) Evolution and role of Pax genes. Curr. Opin. Genet. Dev. 3, 595-605
9. Stuart, E. T., Kioussi, C. and Gruss, P. (1994) Mammalian Pax genes. Annu. Rev. Genet. 28, 219-236
10. Walther, C., Guenet, J. L., Simon, D., Deutsch, U., Jostes, B., Goulding, M. D., Plachov, D., Balling, R. and Gruss, P. (1991) Pax: a murine multigene family of paired box-containing genes. Genomics 11, 424-434
11. Xu, W., Rould, M. A., Jun, S., Desplan, C. and Pabo, C. O. (1995) Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations. Cell 80, 639-650
12. Bertuccioli, C., Fasano, L., Jun, S., Wang, S., Sheng, G. and Desplan, C. (1996) In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product. Development 122, 2673-2685
13. Jun, S. and Desplan, C. (1996) Cooperative interactions between paired domain and homeodomain. Development 122, 2639-2650
14. Miskiewicz, P., Morrissey, D., Lan, Y., Raj, L., Kessler, S., Fujioka, M., Goto, T. and Weir, M. (1996) Both the paired domain and homeodomain are required for in vivo function of Drosophila Paired. Development 122, 2709-2718
15. Fujioka, M., Miskiewicz, P., Raj, L., Gulledge, A. A., Weir, M. and Goto, T. (1996) Drosophila Paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain. Development 122, 2697-2707
16. Czerny, T., Schaffner, G. and Busslinger, M. (1993) DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7, 2048-2061
17. Chalepakis, G., Jones, F. S., Edelman, G. M. and Gruss, P. (1994) Pax-3 contains domains for transcription activation and transcription inhibition. Proc. Natl. Acad. Sci. U.S.A. 91, 12745-12749
18. Dorfler, P. and Busslinger, M. (1996) C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8. EMBO J. 15, 1971-1982
19. Kozmik, Z., Kurzbauer, R., Dorfler, P. and Busslinger, M. (1993) Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties. Mol. Cell. Biol. 13, 6024-6035
20. Plachov, D., Chowdhury, K., Walther, C., Simon, D., Guenet, J. L. and Gruss, P. (1990) Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development 110, 643-651
21. Mansouri, A., Chowdhury, K. and Gruss, P. (1998) Follicular cells of the thyroid gland require Pax8 gene function. Nat Genet. 19, 87-90
22. Pasca di Magliano, M., Di Lauro, R. and Zannini, M. (2000) Pax8 has a key role in thyroid cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 97, 13144-13149
23. Damante, G. and Di Lauro, R. (1994) Thyroid-specific gene expression. Biochim. Biophys. Acta 1218, 255-266
24. Damante, G., Tell, G. and Di Lauro, R. (2001) A unique combination of transcription factors controls differentiation of thyroid cells. Prog. Nucleic Acid Res. Mol. Biol. 66, 307-356
25. Zannini, M., Francis-Lang, H., Plachov, D. and Di Lauro, R. (1992) Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters. Mol. Cell. Biol. 12, 4230-4241
26. Fabbro, D., Pellizzari, L., Mercuri, F., Tell, G. and Damante, G. (1998) Pax-8 protein levels regulate thyroglobulin gene expression. J. Mol. Endocrinol. 21, 347-354
27. Javaux, F., Bertaux, F., Donda, A., Francis-Lang, H., Vassart, G., Di Lauro, R. and Christophe, D. (1992) Functional role of TTF-1 binding sites in bovine thyroglobulin promoter. FEBS Lett. 300, 222-226
28. Espinoza, C. R., Schmitt, T. L. and Loos, U. (2001) Thyroid transcription factor 1 and Pax8 synergistically activate the promoter of the human thyroglobulin gene. J. Mol. Endocrinol. 27, 59-67
29. Di Palma, T., Nitsch, R., Mascia, A., Nitsch, L., Di Lauro, R. and Zannini, M. (2003) The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription. J. Biol. Chem. 278, 3395-3402
30. Yan, C., Naltner, A., Conkright, J. and Ghaffari, M. (2001) Protein-protein interaction of retinoic acid receptor alpha and thyroid transcription factor-1 in respiratory epithelial cells. J. Biol. Chem. 276, 21686-21691
31. Sever-Chroneos, Z., Bachurski, C. J., Yan, C. and Whitsett, J. A. (1999) Regulation of mouse SP-B gene promoter by AP-1 family members. Am. J. Physiol. 277, L79-L88
32. Yang, Y. S., Yang, M. C., Wang, B. and Weissler, J. C. (2001) BR22, a novel protein, interacts with thyroid transcription factor-1 and activates the human surfactant protein B promoter. Am. J. Respir. Cell Mol. Biol. 24, 30-37
33. Yi, M., Tong, G. X., Murry, B. and Mendelson, C. R. (2002) Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1). J. Biol. Chem. 277, 2997-3005
34. Missero, C., Pirro, M. T., Simeone, S., Pischetola, M. and Di Lauro, R. (2001) The DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcription. J. Biol. Chem. 276, 33569-33575
35. Liu, C., Glasser, S. W., Wan, H. and Whitsett, J. A. (2002) GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J. Biol. Chem. 277, 4519-4525
36. Fitzsimmons, D., Hodsdon, W., Wheat, W., Maira, S. M., Wasylyk, B. and Hagman, J. (1996) Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter. Genes Dev. 10, 2198-2211
37. Wheat, W., Fitzsimmons, D., Lennox, H., Krautkramer, S. R., Gentile, L. N., McIntosh, L. P. and Hagman, J. (1999) The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes. Mol. Cell. Biol. 19, 2231-2241
38. Chen, H. I. and Sudol, M. (1995) The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl. Acad. Sci. U.S.A. 92, 7819-7823
39. Sinclair, A. J., Lonigro, R., Civitareale, D., Ghibelli, L. and Di Lauro, R. (1990) The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors. Eur. J. Biochem. 193, 311-318
40. Francis-Lang, H., Price, M., Polycarpou-Schwarz, M. and Di Lauro, R. (1992) Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Mol. Cell. Biol. 12, 576-588
41. Ohno, M., Zannini, M., Levy, O., Carrasco, N. and Di Lauro, R. (1999) The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol. Cell. Biol. 19, 2051-2060
42. Ambesi-Impiombato, F. S. and Coon, H. G. (1979) Thyroid cells in culture. Int. Rev. Cytol. 10, 163-172
43. Bork, P. and Sudol, M. (1994) The WW domain: a signalling site in dystrophin? Trends Biochem. Sci. 19, 531-533
44. Sudol, M., Chen, H. I., Bougeret, C., Einbond, A. and Bork, P. (1995) Characterization of a novel protein-binding module - the WW domain. FEBS Lett. 369, 67-71
45. Mansouri, A., Goudreau, G. and Gruss, P. (1999) Pax genes and their role in organogenesis. Cancer Res 59, 1707s-1709s (discussion 1709s-1710s)
46. Mansouri, A., Hallonet, M. and Gruss, P. (1996) Pax genes and their roles in cell differentiation and development. Curr. Opin. Cell Biol. 8, 851-857
47. Stuart, E. T. and Gruss, P. (1996) PAX: developmental control genes in cell growth and differentiation. Cell Growth Differ. 7, 405-412
48. Macchia, P. E., Lapi, P., Krude, H., Pirro, M. T., Missero, C., Chiovato, L., Souabni, A., Baserga, M., Tassi, V., Pinchera, A. et al. (1998) PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis. Nat. Genet. 19, 83-86
49. Vilain, C., Rydlewski, C., Duprez, L., Heinrichs, C., Abramowicz, M., Malvaux, P., Renneboog, B., Parma, J., Costagliola, S. and Vassart, G. (2001) Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8. J. Clin. Endocrinol. Metab. 86, 234-238
50. Congdon, T., Nguyen, L. Q., Nogueira, C. R., Habiby, R. L., Medeiros-Neto, G. and Kopp, P. (2001) A novel mutation (Q40P) in PAX8 associated with congenital hypothyroidism and thyroid hypoplasia: evidence for phenotypic variability in mother and child. J. Clin. Endocrinol. Metab. 86, 3962-3967
51. Sudol, M., Sliwa, K. and Russo, T. (2001) Functions of WW domains in the nucleus. FEBS Lett. 490, 190-195
52. Yagi, R., Chen, L. F., Shigesada, K., Murakami, Y. and Ito, Y. (1999) A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 18, 2551-2562
53. Waragai, M., Lammers, C. H., Takeuchi, S., Imafuku, I., Udagawa, Y., Kanazawa, I., Kawabata, M., Mouradian, M. M. and Okazawa, H. (1999) PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival. Hum. Mol. Genet. 8, 977-987
54. Sudol, M. and Hunter, T. (2000) NeW wrinkles for an old domain. Cell 103, 1001-1004