메뉴 건너뛰기




Volumn 40, Issue 14-15, 2004, Pages 1003-1008

Recognition and function in a degenerate immune system

Author keywords

Autoimmunity; Cancer; Degeneracy; Molecular mimicry; Self recognition; TCR

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR;

EID: 1242270587     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2003.11.002     Document Type: Article
Times cited : (21)

References (40)
  • 2
    • 0027505094 scopus 로고
    • Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunity
    • Bhardwaj V., Kumar V., Geysen H.M., Sercarz E.E. Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunity. J. Immunol. 151:1993;5000-5010.
    • (1993) J. Immunol. , vol.151 , pp. 5000-5010
    • Bhardwaj, V.1    Kumar, V.2    Geysen, H.M.3    Sercarz, E.E.4
  • 3
    • 0141678964 scopus 로고    scopus 로고
    • Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    • Bynoe M.S., Evans J.T., Viret C., Janeway C.A. Jr. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity. 19:2003;317-328.
    • (2003) Immunity , vol.19 , pp. 317-328
    • Bynoe, M.S.1    Evans, J.T.2    Viret, C.3    Janeway, C.A.Jr.4
  • 4
    • 0032498339 scopus 로고    scopus 로고
    • An introduction to fuzzy systems
    • Dubois D., Prade H. An introduction to fuzzy systems. Clin. Chim. Acta. 270(1):1998;1-29.
    • (1998) Clin. Chim. Acta , vol.270 , Issue.1 , pp. 1-29
    • Dubois, D.1    Prade, H.2
  • 5
    • 0035923604 scopus 로고    scopus 로고
    • Degeneracy and complexity in biological systems
    • Edelman G.M., Gally J.A. Degeneracy and complexity in biological systems. Proc. Natl. Acad. Sci. U.S.A. 98:2001;13763-13768.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 13763-13768
    • Edelman, G.M.1    Gally, J.A.2
  • 6
    • 85030903394 scopus 로고
    • The road not taken. In: Mountain Interval Henry Holt and Co., New York
    • Frost, R., 1920. The road not taken. In: Mountain Interval. Henry Holt and Co., New York.
    • (1920)
    • Frost, R.1
  • 7
    • 0022375427 scopus 로고
    • Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
    • Fujinami R.S., Oldstone M.B. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity. Science. 230:1985;1043-1045.
    • (1985) Science , vol.230 , pp. 1043-1045
    • Fujinami, R.S.1    Oldstone, M.B.2
  • 8
    • 0035811034 scopus 로고    scopus 로고
    • Kinetics and thermodynamics of T cell receptor-autoantigen interactions in murine experimental autoimmune encephalomyelitis
    • Garcia K.C., Radu C.G., Ho J., Ober R.J., Ward E.S. Kinetics and thermodynamics of T cell receptor-autoantigen interactions in murine experimental autoimmune encephalomyelitis. Proc. Natl. Acad Sci. U.S.A. 98:2001;6818-6823.
    • (2001) Proc. Natl. Acad Sci. U.S.A. , vol.98 , pp. 6818-6823
    • Garcia, K.C.1    Radu, C.G.2    Ho, J.3    Ober, R.J.4    Ward, E.S.5
  • 9
    • 0026624906 scopus 로고
    • A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis
    • Gautam A.M., Pearson C.I., Smilek D.E., Steinman L., McDevitt H.O. A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis. J. Exp. Med. 176:1992;605-609.
    • (1992) J. Exp. Med. , vol.176 , pp. 605-609
    • Gautam, A.M.1    Pearson, C.I.2    Smilek, D.E.3    Steinman, L.4    McDevitt, H.O.5
  • 10
    • 0028953288 scopus 로고
    • Hindrance of binding to class II major histocompatibility complex molecules by a single amino acid residue contiguous to a determinant leads to crypticity of the determinant as well as lack of response to the protein antigen
    • Grewal I.S., Moudgil K.D., Sercarz E.E. Hindrance of binding to class II major histocompatibility complex molecules by a single amino acid residue contiguous to a determinant leads to crypticity of the determinant as well as lack of response to the protein antigen. Proc. Natl. Acad Sci. U.S.A. 92:1995;1779-1783.
    • (1995) Proc. Natl. Acad Sci. U.S.A. , vol.92 , pp. 1779-1783
    • Grewal, I.S.1    Moudgil, K.D.2    Sercarz, E.E.3
  • 12
    • 1242270594 scopus 로고    scopus 로고
    • T cell receptors: Affinities, cross-reactivities, and a conformer model
    • issue
    • Holler, P.D., Kranz, D.M., 2003. T cell receptors: affinities, cross-reactivities, and a conformer model. Mol. Immunol. 40, this issue doi: S0161-5890(03)00337-7 .
    • (2003) Mol. Immunol. , vol.40
    • Holler, P.D.1    Kranz, D.M.2
  • 13
    • 0037470496 scopus 로고    scopus 로고
    • Antibody multispecificity mediated by conformational diversity
    • James L.C., Roversi P., Tawfik D.S. Antibody multispecificity mediated by conformational diversity. Science. 299:2003;1362-1367.
    • (2003) Science , vol.299 , pp. 1362-1367
    • James, L.C.1    Roversi, P.2    Tawfik, D.S.3
  • 17
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 18
    • 0028849807 scopus 로고
    • Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon gamma by T cells
    • Kumar V., Bhardwaj V., Soares L., Alexander J., Sette A., Sercarz E. Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon gamma by T cells. Proc. Natl. Acad. Sci. U.S.A. 92:1995;9510-9514.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 9510-9514
    • Kumar, V.1    Bhardwaj, V.2    Soares, L.3    Alexander, J.4    Sette, A.5    Sercarz, E.6
  • 19
    • 0032534725 scopus 로고    scopus 로고
    • Induction or protection from experimental autoimmune encephalomyelitis depends on the cytokine secretion profile of TCR peptide-specific regulatory CD4 T cells
    • Kumar V., Sercarz E. Induction or protection from experimental autoimmune encephalomyelitis depends on the cytokine secretion profile of TCR peptide-specific regulatory CD4 T cells. J. Immunol. 161:1998;6585-6591.
    • (1998) J. Immunol. , vol.161 , pp. 6585-6591
    • Kumar, V.1    Sercarz, E.2
  • 20
    • 0035191130 scopus 로고    scopus 로고
    • An integrative model of regulation centered on recognition of TCR peptide/MHC complexes
    • Kumar V., Sercarz E. An integrative model of regulation centered on recognition of TCR peptide/MHC complexes. Immunol. Rev. 182:2001;113-121.
    • (2001) Immunol. Rev. , vol.182 , pp. 113-121
    • Kumar, V.1    Sercarz, E.2
  • 21
    • 0036644686 scopus 로고    scopus 로고
    • Promiscuous gene expression and central T-cell tolerance: More than meets the eye
    • Kyewski B., Derbinski J., Klein L. Promiscuous gene expression and central T-cell tolerance: more than meets the eye. Trends Immunol. 23:2002;364-371.
    • (2002) Trends Immunol. , vol.23 , pp. 364-371
    • Kyewski, B.1    Derbinski, J.2    Klein, L.3
  • 23
    • 0036036381 scopus 로고    scopus 로고
    • Beyond self and nonself: Fuzzy recognition of the immune system
    • Leng Q., Bentwich Z. Beyond self and nonself: fuzzy recognition of the immune system. Scand. J. Immunol. 56:2002;224-232.
    • (2002) Scand. J. Immunol. , vol.56 , pp. 224-232
    • Leng, Q.1    Bentwich, Z.2
  • 25
    • 0034979180 scopus 로고    scopus 로고
    • Self-reactive T cells and degeneracy of T cell recognition: Evolving concepts-from sequence homology to shape mimicry and TCR flexibility
    • Maverakis E., van den Elzen P., Sercarz E.E. Self-reactive T cells and degeneracy of T cell recognition: evolving concepts-from sequence homology to shape mimicry and TCR flexibility. J. Autoimmunity. 16:2001;201-209.
    • (2001) J. Autoimmunity , vol.16 , pp. 201-209
    • Maverakis, E.1    Van Den Elzen, P.2    Sercarz, E.E.3
  • 27
    • 0030060155 scopus 로고    scopus 로고
    • Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues
    • Moudgil K.D., Grewal I.S., Jensen P.E., Sercarz E.E. Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues. J. Exp. Med. 183:1996;535-546.
    • (1996) J. Exp. Med. , vol.183 , pp. 535-546
    • Moudgil, K.D.1    Grewal, I.S.2    Jensen, P.E.3    Sercarz, E.E.4
  • 28
    • 0031595750 scopus 로고    scopus 로고
    • Modulation of the immunogenicity of antigenic determinants by their flanking residues
    • Moudgil K.D., Sercarz E.E., Grewal I.S. Modulation of the immunogenicity of antigenic determinants by their flanking residues. Immunol. Today. 19:1998;217-220.
    • (1998) Immunol. Today , vol.19 , pp. 217-220
    • Moudgil, K.D.1    Sercarz, E.E.2    Grewal, I.S.3
  • 30
    • 0005265676 scopus 로고
    • Elaboration of antibodies by single cells
    • Nossal G.J., Makela O. Elaboration of antibodies by single cells. Annu. Rev. Microbiol. 16:1962;53-74.
    • (1962) Annu. Rev. Microbiol. , vol.16 , pp. 53-74
    • Nossal, G.J.1    Makela, O.2
  • 33
    • 0141832121 scopus 로고    scopus 로고
    • MHC-guided processing: Binding of large antigen fragments
    • Sercarz E.E., Maverakis E. MHC-guided processing: binding of large antigen fragments. Nat. Rev. Immunol. 3:2003;621-629.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 621-629
    • Sercarz, E.E.1    Maverakis, E.2
  • 35
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology
    • Sloan-Lancaster J., Allen P.M. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1996;1-27.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 1-27
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 38
    • 37049242573 scopus 로고
    • Immunological specificity, unique combinations of selected natural globulins provide an alternative to the classical concept
    • Talmage D. Immunological specificity, unique combinations of selected natural globulins provide an alternative to the classical concept. Science. 129:1959;1643-1648.
    • (1959) Science , vol.129 , pp. 1643-1648
    • Talmage, D.1
  • 39
    • 0033558119 scopus 로고    scopus 로고
    • Dose-dependent induction of distinct anergic phenotypes: Multiple levels of T cell energy
    • Taams L.S., van Eden W., Wauben M.H. Dose-dependent induction of distinct anergic phenotypes: multiple levels of T cell energy. J. Immunol. 162:1999;1974-1981.
    • (1999) J. Immunol. , vol.162 , pp. 1974-1981
    • Taams, L.S.1    Van Eden, W.2    Wauben, M.H.3
  • 40
    • 0022974996 scopus 로고
    • T cell epitope of the auto antigen myelin basic protein that induces encephalomyelitis
    • Zamvil S.S., Mitchell D.J., Moore A.C., Kitamura K., Steinman L., Rothbard J.B. T cell epitope of the auto antigen myelin basic protein that induces encephalomyelitis. Nature. 364:1986;258-266.
    • (1986) Nature , vol.364 , pp. 258-266
    • Zamvil, S.S.1    Mitchell, D.J.2    Moore, A.C.3    Kitamura, K.4    Steinman, L.5    Rothbard, J.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.