메뉴 건너뛰기




Volumn 1, Issue 3, 2002, Pages 75-80

Ondansetron with and without naltrexone as a treatment of biologic alcoholism: Concepts and updated findings

Author keywords

Alcoholism; Humans; Naltrexone; Ondansetron; Subtype; Treatment

Indexed keywords

NALTREXONE; ONDANSETRON; PLACEBO;

EID: 1242268203     PISSN: 15315754     EISSN: None     Source Type: Journal    
DOI: 10.1097/00132576-200209000-00001     Document Type: Review
Times cited : (4)

References (82)
  • 1
    • 0001535923 scopus 로고
    • The effectiveness of alcoholism treatment methods: What research reveals
    • Miller WR, Heather N, eds, New York, NY: Plenum;
    • Miller WR, Hester RK. The effectiveness of alcoholism treatment methods: what research reveals. In: Miller WR, Heather N, eds. Treating Addictive Behaviors: Process of Change. New York, NY: Plenum; 1986:121-174.
    • (1986) Treating Addictive Behaviors: Process of Change , pp. 121-174
    • Miller, W.R.1    Hester, R.K.2
  • 2
    • 0003276205 scopus 로고    scopus 로고
    • Drug therapy for alcohol dependence
    • Swift RM. Drug therapy for alcohol dependence. N Engl J Med 1999;340:1482-1490.
    • (1999) N Engl J Med , vol.340 , pp. 1482-1490
    • Swift, R.M.1
  • 3
    • 0026759536 scopus 로고
    • Neural mechanisms of drug reinforcement
    • Koob GF. Neural mechanisms of drug reinforcement. Ann N Y Acad Sci 1992;654:171-191.
    • (1992) Ann N Y Acad Sci , vol.654 , pp. 171-191
    • Koob, G.F.1
  • 5
    • 0034071789 scopus 로고    scopus 로고
    • Neuropharmacological treatments for alcoholism: Scientific basis and clinical findings
    • Johnson BA, Ait-Daoud N. Neuropharmacological treatments for alcoholism: scientific basis and clinical findings. Psychopharmacology 2000;149:327-344.
    • (2000) Psychopharmacology , vol.149 , pp. 327-344
    • Johnson, B.A.1    Ait-Daoud, N.2
  • 6
    • 0033062757 scopus 로고    scopus 로고
    • The comparative validity of eleven alcoholism typologies
    • Penick EC, Nickel EJ, Powell BJ, et al. The comparative validity of eleven alcoholism typologies. J Stud Alcohol 1999;60:188-202.
    • (1999) J Stud Alcohol , vol.60 , pp. 188-202
    • Penick, E.C.1    Nickel, E.J.2    Powell, B.J.3
  • 7
    • 0025356345 scopus 로고
    • Clinical importance of age at onset in type 1 and type 2 primary alcoholics
    • Irwin M, Schuckit M, Smith TL. Clinical importance of age at onset in type 1 and type 2 primary alcoholics. Arch Gen Psychiatry 1990;47:320-324.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 320-324
    • Irwin, M.1    Schuckit, M.2    Smith, T.L.3
  • 8
    • 0023584108 scopus 로고
    • Personality traits in subtypes of alcoholics
    • von Knorring L, Smigan L, et al. Personality traits in subtypes of alcoholics. J Stud Alcohol 1987;48:523-527.
    • (1987) J Stud Alcohol , vol.48 , pp. 523-527
    • von Knorring, L.1    Smigan, L.2
  • 9
    • 0026793480 scopus 로고
    • Types of alcoholics: Concurrent and predictive validity of some common classification schemes
    • Babor TF, Dolinsky ZS, Meyer RE, et al. Types of alcoholics: concurrent and predictive validity of some common classification schemes. Br J Addict 1992;87:1415-1431.
    • (1992) Br J Addict , vol.87 , pp. 1415-1431
    • Babor, T.F.1    Dolinsky, Z.S.2    Meyer, R.E.3
  • 10
    • 0034018227 scopus 로고    scopus 로고
    • Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient population
    • Johnson BA, Cloninger CR, Roache JD, et al. Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient population. Am J Addict 2000;9:17-27.
    • (2000) Am J Addict , vol.9 , pp. 17-27
    • Johnson, B.A.1    Cloninger, C.R.2    Roache, J.D.3
  • 11
    • 0029983167 scopus 로고    scopus 로고
    • Gianoulakis C, Krishnan B, Thavundayil J. Enhanced sensitivity of pituitary beta-endorphin to ethanol in subjects at high risk of alcoholism [published erratum appears in Arch Gen Psychiatry 1996;53:555]. Arch Gen Psychiatry 1996;53:250-257.
    • Gianoulakis C, Krishnan B, Thavundayil J. Enhanced sensitivity of pituitary beta-endorphin to ethanol in subjects at high risk of alcoholism [published erratum appears in Arch Gen Psychiatry 1996;53:555]. Arch Gen Psychiatry 1996;53:250-257.
  • 12
    • 0029868373 scopus 로고    scopus 로고
    • Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics
    • Fils-Aime ML, Eckardt MJ, George DT, et al. Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. Arch Gen Psychiatry 1996;53:211-216.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 211-216
    • Fils-Aime, M.L.1    Eckardt, M.J.2    George, D.T.3
  • 13
    • 0000008901 scopus 로고    scopus 로고
    • Relationships of plasma tryptophan availability to course of illness and clinical features of alcoholism: A preliminary study
    • Swann AC, Johnson BA, Cloninger CR, et al. Relationships of plasma tryptophan availability to course of illness and clinical features of alcoholism: a preliminary study. Psychopharmacology 1999;143:380-384.
    • (1999) Psychopharmacology , vol.143 , pp. 380-384
    • Swann, A.C.1    Johnson, B.A.2    Cloninger, C.R.3
  • 14
    • 0028110689 scopus 로고
    • Serotonin and alcohol intake, abuse, and dependence: Clinical evidence
    • LeMarquand D, Pihl RO, Benkelfat C. Serotonin and alcohol intake, abuse, and dependence: clinical evidence. Biol Psychiatry 1994;36:326-337.
    • (1994) Biol Psychiatry , vol.36 , pp. 326-337
    • LeMarquand, D.1    Pihl, R.O.2    Benkelfat, C.3
  • 15
    • 0026015298 scopus 로고
    • Ethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in neuroblastoma cells and isolated adult mammalian neurons
    • Lovinger DM, White G. Ethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in neuroblastoma cells and isolated adult mammalian neurons. Mol Pharmacol 1991;40:263-270.
    • (1991) Mol Pharmacol , vol.40 , pp. 263-270
    • Lovinger, D.M.1    White, G.2
  • 16
    • 0030426270 scopus 로고    scopus 로고
    • Pharmacologic characteristics of potentiation of 5-HT3 receptors by alcohols and diethyl ether in NCB-20 neuroblastoma cells
    • Zhou Q, Lovinger DM. Pharmacologic characteristics of potentiation of 5-HT3 receptors by alcohols and diethyl ether in NCB-20 neuroblastoma cells. J Pharmacol Exp Ther 1996;278:732-740.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 732-740
    • Zhou, Q.1    Lovinger, D.M.2
  • 17
    • 0028593865 scopus 로고
    • Alcohols potentiate ion current mediated by recombinant 5-HT3RA receptors expressed in a mammalian cell line
    • Lovinger DM, Zhou Q. Alcohols potentiate ion current mediated by recombinant 5-HT3RA receptors expressed in a mammalian cell line. Neuropharmacology 1994;33:1567-1572.
    • (1994) Neuropharmacology , vol.33 , pp. 1567-1572
    • Lovinger, D.M.1    Zhou, Q.2
  • 18
    • 0025918190 scopus 로고
    • Inhibition of 5-HT3 receptor-mediated ion current by divalent metal cations in NCB-20 neuroblastoma cells
    • Lovinger DM. Inhibition of 5-HT3 receptor-mediated ion current by divalent metal cations in NCB-20 neuroblastoma cells. J Neurophysiol 1991;66:1329-1337.
    • (1991) J Neurophysiol , vol.66 , pp. 1329-1337
    • Lovinger, D.M.1
  • 19
    • 0026363070 scopus 로고
    • Ethanol potentiates ion current mediated by 5-HT3 receptors on neuroblastoma cells and isolated neurons
    • Lovinger DM. Ethanol potentiates ion current mediated by 5-HT3 receptors on neuroblastoma cells and isolated neurons. Alcohol Alcohol Suppl 1991;1:181-185.
    • (1991) Alcohol Alcohol Suppl , vol.1 , pp. 181-185
    • Lovinger, D.M.1
  • 20
    • 0032587957 scopus 로고    scopus 로고
    • 5-HT3 receptors and the neural actions of alcohols: An increasingly exciting topic
    • Lovinger DM. 5-HT3 receptors and the neural actions of alcohols: an increasingly exciting topic. Neurochem Int 1999;35:125-130.
    • (1999) Neurochem Int , vol.35 , pp. 125-130
    • Lovinger, D.M.1
  • 21
    • 0027761397 scopus 로고
    • Alcohol-induced reinforcement: Dopamine and 5-HT3 receptor interactions in animals and humans
    • Johnson BA, Cowen PJ. Alcohol-induced reinforcement: dopamine and 5-HT3 receptor interactions in animals and humans. Drug Dev Res 1993;30:153-169.
    • (1993) Drug Dev Res , vol.30 , pp. 153-169
    • Johnson, B.A.1    Cowen, P.J.2
  • 22
    • 0023426876 scopus 로고
    • A psychomotor stimulant theory of addiction
    • Wise RA, Bozarth MA. A psychomotor stimulant theory of addiction. Psychol Rev 1987:94:469-492.
    • (1987) Psychol Rev , vol.94 , pp. 469-492
    • Wise, R.A.1    Bozarth, M.A.2
  • 23
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Barnes NM, Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999;38:1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 24
    • 0023550693 scopus 로고
    • Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding
    • Kilpatrick GJ, Jones BJ, Tyers MB. Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding. Nature 1987;330:746-748.
    • (1987) Nature , vol.330 , pp. 746-748
    • Kilpatrick, G.J.1    Jones, B.J.2    Tyers, M.B.3
  • 25
    • 0027012573 scopus 로고
    • Ondansetron and related 5-HT3 antagonists: Recent advances
    • Oxford AW, Bell JA, Kilpatrick GJ, et al. Ondansetron and related 5-HT3 antagonists: recent advances. Prog Med Chem 1992;29:239-270.
    • (1992) Prog Med Chem , vol.29 , pp. 239-270
    • Oxford, A.W.1    Bell, J.A.2    Kilpatrick, G.J.3
  • 26
    • 0029665344 scopus 로고    scopus 로고
    • 5-HT3 and 5-HT4 receptors in terminal regions of the mesolimbic system
    • Kilpatrick GJ, Hagan RM, Gale JD. 5-HT3 and 5-HT4 receptors in terminal regions of the mesolimbic system. Behav Brain Res 1996;73:11-13.
    • (1996) Behav Brain Res , vol.73 , pp. 11-13
    • Kilpatrick, G.J.1    Hagan, R.M.2    Gale, J.D.3
  • 27
    • 0343933624 scopus 로고
    • Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
    • Di Chiara G, Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 1988;85:5274-5278.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5274-5278
    • Di Chiara, G.1    Imperato, A.2
  • 28
    • 0025854385 scopus 로고
    • MDL 72222, a selective 5-HT3 receptor antagonist, suppresses voluntary ethanol consumption in alcohol-preferring rats
    • Fadda F, Garau B, Marchei F, et al. MDL 72222, a selective 5-HT3 receptor antagonist, suppresses voluntary ethanol consumption in alcohol-preferring rats. Alcohol Alcohol 1991;26:107-110.
    • (1991) Alcohol Alcohol , vol.26 , pp. 107-110
    • Fadda, F.1    Garau, B.2    Marchei, F.3
  • 29
    • 0026567987 scopus 로고
    • Alcohol stimulates the release of dopamine and serotonin in the nucleus accumbens
    • Yoshimoto K, McBride WJ, Lumeng L, et al. Alcohol stimulates the release of dopamine and serotonin in the nucleus accumbens. Alcohol 1992;9:17-22.
    • (1992) Alcohol , vol.9 , pp. 17-22
    • Yoshimoto, K.1    McBride, W.J.2    Lumeng, L.3
  • 30
    • 0031596715 scopus 로고    scopus 로고
    • The central 5-HT3 receptor in CNS disorders
    • Bloom FE, Morales M. The central 5-HT3 receptor in CNS disorders. Neurochem Res 1998;23:653-659.
    • (1998) Neurochem Res , vol.23 , pp. 653-659
    • Bloom, F.E.1    Morales, M.2
  • 31
    • 0030299793 scopus 로고    scopus 로고
    • Possibility of 5-HT3 receptor involvement in alcohol dependence: A microdialysis study of nucleus accumbens dopamine and serotonin release in rats with chronic alcohol consumption
    • Yoshimoto K, Yayama K, Sorimachi Y, et al. Possibility of 5-HT3 receptor involvement in alcohol dependence: a microdialysis study of nucleus accumbens dopamine and serotonin release in rats with chronic alcohol consumption. Alcohol Clin Exp Res 1996;20(9 suppl):311A-319A.
    • (1996) Alcohol Clin Exp Res , vol.20 , Issue.9 SUPPL.
    • Yoshimoto, K.1    Yayama, K.2    Sorimachi, Y.3
  • 32
    • 0022348735 scopus 로고
    • Laterality of dopamine function and neuroleptic action in the amygdala in the rat
    • Bradbury AJ, Costall B, Domeney AM, et al. Laterality of dopamine function and neuroleptic action in the amygdala in the rat. Neuropharmacology 1985;24:1163-1170.
    • (1985) Neuropharmacology , vol.24 , pp. 1163-1170
    • Bradbury, A.J.1    Costall, B.2    Domeney, A.M.3
  • 33
    • 0025194143 scopus 로고
    • Effect of 5-HT3 receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the rat
    • Hagan RM, Jones BJ, Jordan CC, et al. Effect of 5-HT3 receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the rat. Br J Pharmacol 1990;99:227-232.
    • (1990) Br J Pharmacol , vol.99 , pp. 227-232
    • Hagan, R.M.1    Jones, B.J.2    Jordan, C.C.3
  • 34
    • 0020041869 scopus 로고
    • Substance P analog, DiMe-C7: Evidence for stability in rat brain and prolonged central actions
    • Eison AS, Iversen SD, Sandberg BE, et al. Substance P analog, DiMe-C7: evidence for stability in rat brain and prolonged central actions. Science 1982;215:188-190.
    • (1982) Science , vol.215 , pp. 188-190
    • Eison, A.S.1    Iversen, S.D.2    Sandberg, B.E.3
  • 35
    • 0023522443 scopus 로고
    • Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain
    • Costall B, Domeney AM, Naylor RJ, et al. Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. Br J Pharmacol 1987;92:881-894.
    • (1987) Br J Pharmacol , vol.92 , pp. 881-894
    • Costall, B.1    Domeney, A.M.2    Naylor, R.J.3
  • 36
    • 0027251777 scopus 로고
    • Specific decreases in ethanol- but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930
    • Hodge CW, Samson HH, Lewis RS, et al. Specific decreases in ethanol- but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930. Alcohol 1993;10:191-196.
    • (1993) Alcohol , vol.10 , pp. 191-196
    • Hodge, C.W.1    Samson, H.H.2    Lewis, R.S.3
  • 37
    • 4243890491 scopus 로고    scopus 로고
    • Intracranial self-administration of ethanol into the posterior VTA of Wistar rats is mediated by 5-HT3 receptors
    • Paper presented at:, Santa Barbara, CA
    • Rodd-Henricks ZA, McKinzie DL, Li TK, et al. Intracranial self-administration of ethanol into the posterior VTA of Wistar rats is mediated by 5-HT3 receptors. Paper presented at: Scientific meeting of the Research Society on Alcoholism; 1999; Santa Barbara, CA.
    • (1999) Scientific meeting of the Research Society on Alcoholism
    • Rodd-Henricks, Z.A.1    McKinzie, D.L.2    Li, T.K.3
  • 38
    • 0027242181 scopus 로고
    • Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: A preliminary study in healthy male volunteers
    • Johnson BA, Campling GM, Griffiths P, et al. Attenuation of some alcohol-induced mood changes and the desire to drink by 5-HT3 receptor blockade: a preliminary study in healthy male volunteers. Psychopharmacology 1993;112:142-144.
    • (1993) Psychopharmacology , vol.112 , pp. 142-144
    • Johnson, B.A.1    Campling, G.M.2    Griffiths, P.3
  • 39
    • 0027223322 scopus 로고
    • Effects of various serotonergic agents on alcohol intake and alcohol preference in Wistar rats selected at two different levels of alcohol preference
    • Meert TF. Effects of various serotonergic agents on alcohol intake and alcohol preference in Wistar rats selected at two different levels of alcohol preference. Alcohol Alcohol 1993;28:157-170.
    • (1993) Alcohol Alcohol , vol.28 , pp. 157-170
    • Meert, T.F.1
  • 40
    • 0029098334 scopus 로고
    • Evidence that the amygdala is involved in the inhibitory effects of 5-HT receptor antagonists on alcohol drinking in rats
    • Dyr W, Kostowski W. Evidence that the amygdala is involved in the inhibitory effects of 5-HT receptor antagonists on alcohol drinking in rats. Alcohol 1995;12:387-391.
    • (1995) Alcohol , vol.12 , pp. 387-391
    • Dyr, W.1    Kostowski, W.2
  • 42
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • McBride WJ, Li TK. Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol 1998;12:339-369.
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 43
    • 0028935339 scopus 로고
    • Effect of the 5-HT3 antagonist ondansetron on voluntary ethanol intake in rats and mice maintained on a limited access procedure
    • Tomkins DM, Le AD, Sellers EM. Effect of the 5-HT3 antagonist ondansetron on voluntary ethanol intake in rats and mice maintained on a limited access procedure. Psychopharmacology 1995;117:479-485.
    • (1995) Psychopharmacology , vol.117 , pp. 479-485
    • Tomkins, D.M.1    Le, A.D.2    Sellers, E.M.3
  • 44
    • 0028169468 scopus 로고
    • Serotonin 5-HT3 antagonists fail to affect ethanol self-administration of rats
    • Beardsley PM, Lopez OT, Gullikson G, et al. Serotonin 5-HT3 antagonists fail to affect ethanol self-administration of rats. Alcohol 1994;11:389-395.
    • (1994) Alcohol , vol.11 , pp. 389-395
    • Beardsley, P.M.1    Lopez, O.T.2    Gullikson, G.3
  • 45
    • 84991184499 scopus 로고
    • Affectivity, family drinking history, and the development of problem drinking: A longitudinal analysis
    • Johnson V, Pandina RJ. Affectivity, family drinking history, and the development of problem drinking: a longitudinal analysis. J Appl Soc Psychol 1993;23:2055-2073.
    • (1993) J Appl Soc Psychol , vol.23 , pp. 2055-2073
    • Johnson, V.1    Pandina, R.J.2
  • 46
    • 0030587480 scopus 로고    scopus 로고
    • Ondansetron alters human alcohol intoxication
    • Swift RM, Davidson D, Whelihan W, et al. Ondansetron alters human alcohol intoxication. Biol Psychiatry 1996;40:514-521.
    • (1996) Biol Psychiatry , vol.40 , pp. 514-521
    • Swift, R.M.1    Davidson, D.2    Whelihan, W.3
  • 47
    • 0028060302 scopus 로고
    • Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers
    • Doty P, Zacny JP, de Wit H. Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers. Behav Pharmacol 1994;5:461-469.
    • (1994) Behav Pharmacol , vol.5 , pp. 461-469
    • Doty, P.1    Zacny, J.P.2    de Wit, H.3
  • 48
    • 0028038381 scopus 로고
    • Clinical efficacy of the 5-HT3 antagonist ondansetron in alcohol abuse and dependence
    • Sellers EM, Toneatto T, Romach MK, et al. Clinical efficacy of the 5-HT3 antagonist ondansetron in alcohol abuse and dependence. Alcohol Clin Exp Res 1994;18:879-885.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 879-885
    • Sellers, E.M.1    Toneatto, T.2    Romach, M.K.3
  • 49
    • 0026080111 scopus 로고
    • A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies
    • Lahiri DK, Nurnberger JI Jr. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 1991;19:5444.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5444
    • Lahiri, D.K.1    Nurnberger Jr, J.I.2
  • 51
    • 0025091688 scopus 로고
    • Benzodiazepines and alcohol
    • Linnoila MI. Benzodiazepines and alcohol. J Psychiatr Res 1990;24(suppl 2):121-127.
    • (1990) J Psychiatr Res , vol.24 , Issue.SUPPL. 2 , pp. 121-127
    • Linnoila, M.I.1
  • 53
    • 0026566499 scopus 로고
    • Biologic correlates of suicidal risk and aggressive behavioral traits
    • Linnoila M, Virkkunen M. Biologic correlates of suicidal risk and aggressive behavioral traits. J Clin Psychophannacol 1992;12(2 supp1):19S-20S.
    • (1992) J Clin Psychophannacol , vol.12 , Issue.2 SUPP1
    • Linnoila, M.1    Virkkunen, M.2
  • 55
    • 0027154210 scopus 로고
    • Effects of fluvoxamine, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers
    • Linnoila M, Stapleton JM, George DT, et al. Effects of fluvoxamine, alone and in combination with ethanol, on psychomotor and cognitive performance and on autonomic nervous system reactivity in healthy volunteers. J Clin Psychophannacol 1993;13:175-180.
    • (1993) J Clin Psychophannacol , vol.13 , pp. 175-180
    • Linnoila, M.1    Stapleton, J.M.2    George, D.T.3
  • 57
    • 0036201983 scopus 로고    scopus 로고
    • Ondansetron reduces the craving of biologically predisposed alcoholics
    • Johnson BA, Roache JD, Ait-Daoud N, et al. Ondansetron reduces the craving of biologically predisposed alcoholics. Psychopharmacology. 2002;160:408-413.
    • (2002) Psychopharmacology , vol.160 , pp. 408-413
    • Johnson, B.A.1    Roache, J.D.2    Ait-Daoud, N.3
  • 58
    • 0033777068 scopus 로고    scopus 로고
    • Serotonergic agents and alcoholism treatment: Rebirth of the subtype concept - an hypothesis
    • Johnson BA. Serotonergic agents and alcoholism treatment: rebirth of the subtype concept - an hypothesis. Alcohol Clin Exp Res 2000;24:1597-1601.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1597-1601
    • Johnson, B.A.1
  • 59
    • 0025114654 scopus 로고
    • Characterization and autoradiographic localization of 5-HT3 receptor recognition sites identified with [3H]-(S)-zacopride in the forebrain of the rat
    • Barnes JM, Barnes NM, Champaneria S, et al. Characterization and autoradiographic localization of 5-HT3 receptor recognition sites identified with [3H]-(S)-zacopride in the forebrain of the rat. Neurophartnacohgy 1990;29:1037-1045.
    • (1990) Neurophartnacohgy , vol.29 , pp. 1037-1045
    • Barnes, J.M.1    Barnes, N.M.2    Champaneria, S.3
  • 60
    • 0025196914 scopus 로고
    • Autoradiography of [3H]quipazine in rodent brain
    • Perry DC. Autoradiography of [3H]quipazine in rodent brain. Eur J Pharmacol 1990;187:75-85.
    • (1990) Eur J Pharmacol , vol.187 , pp. 75-85
    • Perry, D.C.1
  • 61
    • 0026645613 scopus 로고
    • Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat
    • Yoshimoto K, McBride WJ. Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat. Neurochem Res 1992;17:401-407.
    • (1992) Neurochem Res , vol.17 , pp. 401-407
    • Yoshimoto, K.1    McBride, W.J.2
  • 62
    • 0029024929 scopus 로고
    • Serotonin-3 receptor and ethanol-stimulated dopamine release in the nucleus accumbens
    • Campbell AD, McBride WJ. Serotonin-3 receptor and ethanol-stimulated dopamine release in the nucleus accumbens. Pharmacol Biochem Behav 1995;51:835-842.
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 835-842
    • Campbell, A.D.1    McBride, W.J.2
  • 63
    • 0024970420 scopus 로고
    • The effect of ethanol on the biosynthesis and regulation of opioid peptides
    • Gianoulakis C. The effect of ethanol on the biosynthesis and regulation of opioid peptides. Experientia 1989;45:428-435.
    • (1989) Experientia , vol.45 , pp. 428-435
    • Gianoulakis, C.1
  • 64
    • 0021592665 scopus 로고
    • Morphine and naloxone modulate intake of ethanol
    • Reid LD, Hunter GA. Morphine and naloxone modulate intake of ethanol. Alcohol 1984;1:33-37.
    • (1984) Alcohol , vol.1 , pp. 33-37
    • Reid, L.D.1    Hunter, G.A.2
  • 65
    • 0023256370 scopus 로고
    • Persistence and specificity of small doses of morphine on intake of alcoholic beverages
    • Hubbell CL, Czirr SA, Reid LD. Persistence and specificity of small doses of morphine on intake of alcoholic beverages. Alcohol 1987;4:149-156.
    • (1987) Alcohol , vol.4 , pp. 149-156
    • Hubbell, C.L.1    Czirr, S.A.2    Reid, L.D.3
  • 66
    • 0022591828 scopus 로고
    • Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations
    • Hubbell CL, Czirr SA, Hunter GA, et al. Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations. Alcohol 1986;3:39-54.
    • (1986) Alcohol , vol.3 , pp. 39-54
    • Hubbell, C.L.1    Czirr, S.A.2    Hunter, G.A.3
  • 67
    • 0023819163 scopus 로고
    • 5-HT3 receptor antagonists block morphine- and nicotine-induced place-preference conditioning
    • Carboni E, Acquas E, Leone P, et al. 5-HT3 receptor antagonists block morphine- and nicotine-induced place-preference conditioning. Eur J Pharmacol 1988;151:159-160.
    • (1988) Eur J Pharmacol , vol.151 , pp. 159-160
    • Carboni, E.1    Acquas, E.2    Leone, P.3
  • 68
    • 0024405626 scopus 로고
    • Differential inhibitory effects of a 5-HT3 antagonist on drug-induced stimulation of dopamine release
    • Carboni E, Acquas E, Frau R, et al. Differential inhibitory effects of a 5-HT3 antagonist on drug-induced stimulation of dopamine release. Eur J Pharmacol 1989;164:515-519.
    • (1989) Eur J Pharmacol , vol.164 , pp. 515-519
    • Carboni, E.1    Acquas, E.2    Frau, R.3
  • 69
    • 0024473488 scopus 로고
    • 5-HT3 receptors control dopamine release in the nucleus accumbens of freely moving rats
    • Imperato A, Angelucci L. 5-HT3 receptors control dopamine release in the nucleus accumbens of freely moving rats. Neurosci Lett 1989;101:214-217.
    • (1989) Neurosci Lett , vol.101 , pp. 214-217
    • Imperato, A.1    Angelucci, L.2
  • 70
    • 0027339314 scopus 로고
    • 5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat
    • Pei Q, Zetterstrom T, Leslie RA, et al. 5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat. Eur J Pharmacol 1993;230:63-68.
    • (1993) Eur J Pharmacol , vol.230 , pp. 63-68
    • Pei, Q.1    Zetterstrom, T.2    Leslie, R.A.3
  • 71
    • 0345085623 scopus 로고    scopus 로고
    • Roles of 5-HT3 and opioid receptors in the ethanol-induced place preference in rats exposed to conditioned fear stress
    • Matsuzawa S, Suzuki T, Misawa M, et al. Roles of 5-HT3 and opioid receptors in the ethanol-induced place preference in rats exposed to conditioned fear stress. Life Sci 1999;64:PL241-PL249.
    • (1999) Life Sci , vol.64
    • Matsuzawa, S.1    Suzuki, T.2    Misawa, M.3
  • 72
    • 0026633569 scopus 로고
    • Ethanol-induced increase in endogenous dopamine release may involve endogenous opiates
    • Widdowson PS, Holman RB. Ethanol-induced increase in endogenous dopamine release may involve endogenous opiates. J Neurochem 1992;59:157-163.
    • (1992) J Neurochem , vol.59 , pp. 157-163
    • Widdowson, P.S.1    Holman, R.B.2
  • 73
    • 0028677857 scopus 로고
    • Interaction between opiate and 5-HT3 receptor antagonists in the regulation of alcohol intake
    • Le AD, Sellers EM. Interaction between opiate and 5-HT3 receptor antagonists in the regulation of alcohol intake. Alcohol Alcohol Suppl 1994;2:545-549.
    • (1994) Alcohol Alcohol Suppl , vol.2 , pp. 545-549
    • AD, L.1    Sellers, E.M.2
  • 74
    • 0035117372 scopus 로고    scopus 로고
    • Combining ondansetron and naltrexone reduces craving among biologically predisposed alcoholics: Preliminary clinical evidence
    • Ait-Daoud N, Johnson BA, Prihoda TJ, et al. Combining ondansetron and naltrexone reduces craving among biologically predisposed alcoholics: preliminary clinical evidence. Psychopharmacology 2001;154:23-27.
    • (2001) Psychopharmacology , vol.154 , pp. 23-27
    • Ait-Daoud, N.1    Johnson, B.A.2    Prihoda, T.J.3
  • 75
    • 0034977292 scopus 로고    scopus 로고
    • Combining ondansetron and naltrexone treats biological alcoholics: Corroboration of self-reported drinking by serum carbohydrate deficient transferrin, a biomarker
    • Ait-Daoud N, Johnson BA, Javors M, et al. Combining ondansetron and naltrexone treats biological alcoholics: corroboration of self-reported drinking by serum carbohydrate deficient transferrin, a biomarker. Alcohol Clin Exp Res 2001;25:847-849.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 847-849
    • Ait-Daoud, N.1    Johnson, B.A.2    Javors, M.3
  • 76
    • 0028283624 scopus 로고
    • Carbohydrate-deficient transferrin and gamma-glutamyltransferase as markers of heavy alcohol consumption: Gender differences
    • Anton RF, Moak DH. Carbohydrate-deficient transferrin and gamma-glutamyltransferase as markers of heavy alcohol consumption: gender differences. Alcohol Clin Exp Res 1994;18:747-754.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 747-754
    • Anton, R.F.1    Moak, D.H.2
  • 77
    • 0026389651 scopus 로고
    • A modified method for the assay of carbohydrate-deficient transferrin (CDT) in serum
    • Stibler H, Borg S, Joustra M. A modified method for the assay of carbohydrate-deficient transferrin (CDT) in serum. Alcohol Alcohol Suppl 1991;1:451-454.
    • (1991) Alcohol Alcohol Suppl , vol.1 , pp. 451-454
    • Stibler, H.1    Borg, S.2    Joustra, M.3
  • 78
    • 0026331891 scopus 로고
    • Carbohydrate-deficient transferrin in serum: A new marker of potentially harmful alcohol consumption reviewed
    • Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin Chem 1991;37:2029-2037.
    • (1991) Clin Chem , vol.37 , pp. 2029-2037
    • Stibler, H.1
  • 80
    • 0030860547 scopus 로고    scopus 로고
    • Naltrexone and alcohol dependence. Role of subject compliance
    • Volpicelli JR, Rhines KC, Rhines JS, et al. Naltrexone and alcohol dependence. Role of subject compliance. Arch Gen Psychiatry 1997;54:737-742.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 737-742
    • Volpicelli, J.R.1    Rhines, K.C.2    Rhines, J.S.3
  • 81
    • 0029553418 scopus 로고
    • Serotonergic mediation of vomiting
    • Gale JD. Serotonergic mediation of vomiting. J Pediatr Gastroenterol Nutr 1995;21(suppl 1):S22-S28.
    • (1995) J Pediatr Gastroenterol Nutr , vol.21 , Issue.SUPPL. 1
    • Gale, J.D.1
  • 82
    • 0029847458 scopus 로고    scopus 로고
    • Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications
    • Wilde MI, Markham A, Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications. Drugs 1996;52:773-794.
    • (1996) Drugs , vol.52 , pp. 773-794
    • Wilde, M.I.1    Markham, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.