Molecular pathological analysis on the mechanism of liver carcinogenesis in dicyclanil-treated mice

Toxicology

Volumn 207, Issue 3, 2005, Pages 419-436

  Moto, Mitsuyoshi ^a,b   Okamura, Miwa ^a,b   Muto, Tomoko ^c   Kashida, Yoko ^a   Machida, Noboru ^a   Mistumori, Kunitoshi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Dicyclanil; Liver carcinogenesis; Microarray; Mouse; Oxidative stress

Indexed keywords

8 OXOGUANINE DNA GLYCOSYLASE 1; ALDEHYDE DEHYDROGENASE; COMPLEMENTARY DNA; CYTOCHROME P450 1A; DIMETHYLNITROSAMINE; DNA GLYCOSYLTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE 45 ALPHA PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXIDOREDUCTASE; PROTEIN; PYRIMIDINE DERIVATIVE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; DNA MICROARRAY; FEEDING; GENE EXPRESSION; HISTOPATHOLOGY; LIVER CARCINOGENESIS; LIVER HISTOLOGY; MALE; METABOLISM; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; OXIDATIVE STRESS; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE;

ANIMALS; DIET; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; JUVENILE HORMONES; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED ICR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

INSECTA; OVIS ARIES;

EID: 12344335872     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.10.011     Document Type: Article

References (33)

1. C.A. Afshari, E.F. Nuwaysir, and J.C. Barrett Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation Cancer Res. 59 1999 4759 4760
2. D. Canistro, G. Cantelli-Forti, G.L. Biagi, and M. Palini Re: Dioxin increases reactive oxygen production in mouse liver mitcondria Toxicol. Appl. Pharmacol. 185 2002 74 75
3. K.C. Cater, A.J. Gandolfi, and I.G. Sipes Characterization of dimethylnitrosamine-induced focal nodular lesions in the livers of new born mice Toxicol. Pathol. 13 1985 3 9
4. H.Z. Chae, S.J. Chung, and S.G. Rhee Thioredoxin-dependent peroxide reductase from yeast J. Biol. Chem. 269 1994 27670 27678
5. H. Chen, J. Liu, B.A. Merrick, and M.P. Waalkes Genetic events associated with arsenic-induced malignant transformation: application of cDNA microarray technology Mol. Carcinog. 30 2001 79 87
6. L. Cheng, M.R. Spitz, W.K. Hong, and Q. Wei Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis Carcinogenesis 21 2000 1527 1530
7. A.J. Fornace Jr., D.W. Nebert, M.C. Hollander, J.D. Luethy, M. Papathanasiou, J. Frgnoli, and N.J. Holbrook Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents Mol. Cell. Biol. 9 1989 4196 4203
8. F.P. Guengerrich, and T. Shimada Oxidation of toxic and carcinogenic chemicals by human cytochrome P450 enzymes Chem. Res. Toxicol. 4 1991 391 407
9. M.C. Hollander, M.S. Sheikh, D. Bulavin, K. Lundren, L. Augeri-Henmueller, R. Shehee, T. Molinaro, K. Kim, E. Tolosa, J.D. Ashwell, M.D. Rosenberg, Q. Zhan, P.M. Ferna'ndez-Salguero, W.F. Morgan, C.X. Deng, and A.J. Fornace Jr. Genomic instability in Gadd45a-deficient mice Nat. Genet. 23 1999 176 184
10. M.C. Hollander, O. Kovalsky, J.M. Salvador, K.E. Kim, A.D. Patterson, D.C. Hairnes, and A.J. Fornace Jr. DMBA carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency Cancer Res. 61 2001 2487 2491
11. M. Iida, C.H. Anna, J. Hartis, M. Bruno, B. Wetmore, J.R. Dubin, S. Sieber, L. Bennett, M.L. Cunningham, R.S. Paules, K.B. Tomer, C.D. Houle, A.B. Merrick, R.C. Sills, and T.R. Devereux Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14, 643 Carcinogenesis 24 2003 757 770
12. R.D. Irwin, G.A. Boorman, M.L. Cunningham, A.N. Heinloth, D.E. Malarkey, and R.S. Paules Application of toxicogenomics to toxicology: basic concepts in the analysis of microarray data Toxicol. Pathol. 32 2004 72 83
13. H. Jeffrey, V.B. Dmitry, R.A.W. Miriam, A.M. Gregory, H. Christine, V. Lilit, and J.F. Albert Jr. Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53 Cancer Res. 62 2002 7305 7315
14. S. Jin, L. Mazzacurati, X. Zhu, T. Tong, Y. Song, S. Shujuan, K.L. Petrik, B. Rajasekaran, M. Wu, and Q. Zhan Gadd45a contribute to p53 stabilization in response to DNA damage Oncogene 22 2003 8536 8540
15. N. Kato, M. Shibutani, H. Takagi, C. Uneyama, K. Lee, S. Takigami, K. Mashima, and M. Hirose Gene expression profile in the livers of rats orally administered ethinylestradiol for 28 days using microarray technique Toxicology 200 2004 179 192
16. WAF1/Cip1, cyclin D1 and Ogg1 Carcinogenesis 24 2002 1389 1399
17. A. Kinoshita, H. Wanibuchi, K. Morimura, M. Wei, J. Shen, S. Imaoka, Y. Funae, and S. Fukushima Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression Carcinogenesis 24 2003 1389 1399
18. T.C. Laurent, E.C. Moore, and P. Reichard Enzymatic synthesis of deoxyribonucleotides. IV. Isolation and characterization of thioredoxin, the hydrogen donor from Escherichia coli B J. Biol. Chem. 239 1964 3436 3444
19. M. Luthman, and A. Holmgren Rat liver thioredoxin and thioredoxin reductase: purification and characterization Biochemistry 21 1982 6628 6633
20. M. Moto, Y. Sasaki, M. Okamura, M. Fujita, Y. Kashida, N. Machida, and K. Mitsumori Absence of in vivo genotoxicity and liver initiation activity of dicyclanil J. Toxicol. Sci. 28 2003 173 179
21. D. Mustacich, and G. Powis Thioredoxin reductase Biochem. J. 346 2000 1 8
22. D. Nakae, Y. Kobayashi, H. Akai, N. Andoh, H. Sato, K. Ohashi, M. Tsutsumi, and Y. Konishi Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylanine Cancer Res. 57 1997 1281 1287
23. S. Puntarulo, and A.I. Cederbaum Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes Free Radic. Biol. Med. 24 1998 1324 1330
24. A.M. Rutenberg, H. Kim, J.W. Fischbein, J.S. Hanker, H.L. Wasserkrug, and A.M. Seligman Histochemical and ultrastructural demonstration of γ-glutamyl transpeptidase activity J. Histochem. Cytochem. 17 1969 517 525
25. A. Sakurai, K. Yasuda, Y. Shoji, S. Himeno, M. Tsujimoto, M. Kunimoto, N. Imura, and S. Hara Over expression of thoredoxin reductase 1 regulates NF-κB activation J. Cell. Physiol. 198 2004 22 30
26. M. Shibutani, N. Takahashi, T. Kobayashi, C. Uneyama, N. Matsutomi, A. Nishikawa, and M. Hirose Molecular profiling of genes up-regulating during promotion by phenobarbital treatment in a medium-term rat liver bioassay Carcinogenesis 23 2002 1047 1055
27. T. Shirai A medium-term rat liver bioassay as a rapid in vivo test for carcinogenic potential: historical review of model development and summary of results from 291 test Toxicol. Pathol. 25 1997 436 460
28. M.L. Smith, J.M. Ford, M.C. Hollander, R.A. Bortnick, S.A. Amundson, Y.R. Seo, C.X. Deng, P.C. Hanawalt, and A.J. Fornace Jr. p53-mediated DNA responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes Mol. Cell. Biol. 20 2000 3705 3714
29. M. Tsuchida, T. Miura, and K. Aibara Lipofuscin and lipofuscin-like substances Chem. Phys. Lipids 44 1987 297 325
30. H. Tsuda, D.S. Sarma, S. Rajalakshmi, J. Zubroff, E. Farber, R.P. Batzinger, Y.N. Cha, and E. Bueding Induction of hepatic neoplastic lesions in mice with a single dose of hycanthone methanesulfonate after partial hepatectomy Cancer Res. 39 1979 4491 4496
31. M. Ueno, H. Masutani, J.R. Arai, A. Yamauchi, K. Hirota, T. Sakai, T. Inamoto, Y. Yamaoka, J. Yodoi, and T. Nikaido Thioredoxin-dependent redox regulation of p53-mediated p21 activation J. Biol. Chem. 274 1999 35809 35815
32. WHO Toxicological evaluation of certain veterinary drug residues in food 54th Meeting of the Joint FAO/WHO Expert Committee on Food Additives. WHO Food Additive Series, vol. 45 ##### 2000 75 89
33. M. Yoshida, K. Miyajima, K. Shiraki, J. Ando, K. Kudoh, D. Nakae, M. Takahashi, and A. Maekawa Hepatotoxicity and consequently increased cell proliferation are associated with flumequine hepatocarcinogenesis in mice Cancer Lett. 141 1999 99 107