Application of 'inductive' QSAR descriptors for quantification of antibacterial activity of cationic polypeptides

Molecules

Volumn 9, Issue 12, 2004, Pages 1034-1052

  Cherkasov, Artem ^a   Jankovic, Bojana ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

Antibacterial peptides; Antibiotics; Inductive descriptors; QSAR

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ARGINYLTRYPTOPHYLLYSYLLEUCYLASPARAGINYLASPARAGINYLASPARAGINYLISOLEUCYLGLYCYLALAN YLARGINYLLEUCYLLYSYLVALYLLEUCINAMIDE; CATION; GLYCYLTRYPTOPHYLARGINYLLEUCYLPHENYLALANYLARGINYLGLYCYLISOLEUCYLARGINYLALANYLVALY LLEUCYLASPARAGINYLVALYLLEUCINAMIDE; GLYCYLTRYPTOPHYLGLUTAMYLLEUCYLGLYCYLGLUTAMYLGLUTAMYLISOLEUCYLLEUCYLASPARAGINYLVA LYLLEUCYLLYSYLVALYLLEUCINAMIDE; GLYCYLTRYPTOPHYLLYSYLLEUCYLGLYCYLLEUCYLLYSYLISOLEUCYLLEUCYLASPARAGINYLVALYLLEUCY LLYSYLVALYLLEUCINAMIDE; HISTIDYLTRYPTOPHYLHISTIDYLLEUCYLHISTIDYLLYSYLHISTIDYLARGINYLGLYCYLALANYLARGINYLH ISTIDYLLYSYLVALYLLEUCINAMIDE; HISTIDYLTRYPTOPHYLLYSYLARGINYLPHENYLALANYLLEUCYLARGINYLISOLEUCYLGLYCYLHISTIDYLAS PARAGINYLLEUCYLASPARAGINYLVALYLASPARAGINAMIDE; HISTIDYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLHISTIDYLVALYLA SPARAGINYLLYSYLARGINYLLEUCINAMIDE; LEUCYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLEUCYLHISTIDYLISOLEUCYLLEUCYLALANYLVALYLL EUCYLLYSYLVALYLLEUCINAMIDE; LYSYLARGINYLGLYCYLLEUCYLPHENYLALANYLLYSYLLYSYLGLYCYLGLYCYLALANYLVALYLLEUCYLLYSYL GLYCYLLEUCINAMIDE; LYSYLASPARAGINYLLYSYLARGINYLASPARAGINYLLYSYLLYSYLISOLEUCYLGLYCYLALANYLVALYLLEUCY LLYSYLVALYLLEUCINAMIDE; LYSYLASPARAGINYLLYSYLLEUCYLGLUTAMYLLYSYLLYSYLISOLEUCYLGLYCYLALANYLVALYLLEUCYLLYS YLVALYLLEUCINAMIDE; LYSYLHISTIDYLASPARAGINYLLEUCYLPHENYLALANYLLYSYLGLYCYLISOLEUCYLGLYCYLALANYLVALYLL EUCYLLEUCYLVALYLLEUCINAMIDE; LYSYLHISTIDYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLALANYLHISTIDYLARGIN YLLYSYLARGINYLASPARAGINAMIDE; LYSYLTRYPTOPHYLASPARAGINYLLEUCYLASPARAGINYLGLYCYLASPARAGINYLISOLEUCYLASPARAGINYL ALANYLVALYLLEUCYLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLGLYCYLLEUCYLPHENYLALANYLLYSYLASPARAGINYLISOLEUCYLGLYCYLALANYLVALY LLEUCYLHISTIDYLVALYLASPARAGINAMIDE; LYSYLTRYPTOPHYLHISTIDYLLEUCYLARGINYLASPARAGINYLLYSYLISOLEUCYLGLYCYLALANYLVALYLAR GINYLASPARAGINYLASPARAGINYLLEUCINAMIDE; LYSYLTRYPTOPHYLHISTIDYLLEUCYLPHENYLALANYLLEUCYLLEUCYLISOLEUCYLLEUCYLALANYLVALYLL EUCYLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLHISTIDYLLEUCYLPHENYLALANYLLEUCYLLYSYLISOLEUCYLLEUCYLALANYLVALYLLE UCYLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLGLYCYLGLUTAMYLLEUCYLGLUTAMYLISOLEUCYLGLUTAMYLALANYLGLUTAMYLL EUCYLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLGLYCYLLYSYLGLYCYLISOLEUCYLGLYCYLALANYLVALYLGLYCYLLYSYL VALYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLASPARAGINYLARGINYLISOLEUCYLGLYCYLHISTIDYLA SPARAGINYLARGINYLLYSYLVALYLASPARAGINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLEUCYLGLYCYLISOLEUCYLLEUCYLALANYLVALYLLEUC YLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLASPARAGINYLASPARAGINYLASPARAGINY LASPARAGINYLASPARAGINYLLYSYLHISTIDYLASPARAGINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLHISTIDYLGLYCYLASPARAGINYLVALYLAR GINYLLYSYLVALYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLASPARAGINYLARGINY LASPARAGINYLLYSYLVALYLLEUCINAMIDE; POLYPEPTIDE; UNCLASSIFIED DRUG;

ACCURACY; ANTIBACTERIAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; DRUG DESIGN; MOLECULAR INTERACTION; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 12344320524     PISSN: 14203049     EISSN: None     Source Type: Journal    
DOI: 10.3390/91201034     Document Type: Article

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