Design of active analogues of a 15-residue peptide using D-optimal design, QSAR and a combinatorial search algorithm

Journal of Peptide Research

Volumn 49, Issue 1, 1997, Pages 89-102

  Mee, Roger P ^a   Auton, Tim R ^a   Morgan, Phillip J ^a  

^a Proteus Molecular Design   (United Kingdom)

Author keywords

Combinatorial search; Covariance; D optimal design; Partial least squares; Peptide; QSAR; Z scales

Indexed keywords

ANTIINFECTIVE AGENT; SYNTHETIC PEPTIDE;

ARTICLE; DRUG DESIGN; HYDROPHOBICITY; MATHEMATICAL MODEL; MINIMUM INHIBITORY CONCENTRATION; PEPTIDE ANALYSIS; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 0030914367     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1997.tb01125.x     Document Type: Article

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