Hyperleptinemia as a risk factor in obesity-related hypertension;Hiperleptinemia como factor de riesgo en hipertensión arterial asociada a obesidad

Medicina Clinica

Volumn 123, Issue 20, 2004, Pages 766-769

  Álvarez Aguilar, Cleto ^a,d   Mondragón Jiménez, Lourdes I ^b   Ramírez Enríquez, Jésus ^e   Gómez García, Anel ^c   Paniagua Sierra, Ramón ^e   Amato, Dante ^e  

^a U de Invest en Epidemiologia Clin   (Mexico)

^b Centro de Investigacion Biomedica   (Mexico)

^c HOSPITAL DE ESPECIALIDADES   (Mexico)

^d Hospital General Regional No 1 IMSS   (Mexico)

^e NONE

Author keywords

Dyslipidemia; High blood pressure; Hyperinsulinemia; Hyperleptinemia; Obesity; Risk factors for cardiovascular disease

Indexed keywords

CHOLESTEROL; CREATININE; INSULIN; LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CONCENTRATION RESPONSE; DYSLIPIDEMIA; FEMALE; HUMAN; HYPERINSULINEMIA; HYPERLEPTINEMIA; HYPERTENSION; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OBESITY; PATHOPHYSIOLOGY; RISK FACTOR;

EID: 12344277748     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1157/13069809     Document Type: Article

References (35)

1. Duncan HP. Obesity and hypertension. Diabetes Care 1991;14:488-504.
2. Hubert HB, Feinlieb M, McNamara PM, Castelli WP. Obesity as an independent risk factor: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983;67:968-77.
3. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Fridman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32.
4. Weigle DS, Bukpwski TR, Foster DC. Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. J Clin Invest 1995;96:2065-70.
5. Considine RV, Sinha MK, Heiman ML, Kriaunciunas A, Stephens TW, Nyce MR, et al. Serum inmunoreactive-leptin concentrations in normal weight and obese humans. N Engl J Med 1996;334:292-5.
6. Montague CT, Pirns JB, Sanders L, Digby JE, O'Rahilly S. Depot- and Sex-specific differences in leptin mRNA expression. Diabetes 1997;46:342-7.
7. Klein S, Coppack SW, Mohamed-Ali V, Landt M. Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes 1996;45:984-7.
8. Masuzaki H, Ogawa Y, Isse N, Satoh N, Okazaki T, Shigemoto M, et al. Human obese gene expression. Diabetes 1995;44:855-8.
9. Budo A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, et al. The stomach is a source of leptin. Nature 1998;394:790-3.
10. Hassink SG, de Lancey E, Sheslow DV, Smith-Kirwin SM, O'Connor DM, Considine RV, et. al. Placental leptin: an important new growth factor in intrauterine and neonatal development? Pediatrics 1997;100:1E-6E.
11. Esler M, Vaz M, Collier G, Nestel P, Jennings G, Kaye D, et al. Leptin in human plasma is derived in part from the brain, and cleared by the kidneys. Lancet 1998;351:879.
12. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995;269:546-9.
13. Cusin I, Rohner-Jeanrenaod F, Stricker-Krongard A, Jeanrenaud B. The weight-reducing effect of an intracerebroventricular bolus inyection of leptin in genetically obese fa/fa rats: reduced sensitivity compared with lean animals. Diabetes 1996;45:1446-50.
14. Elmquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB. Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology 1997;138:839-42.
15. Haynes WG, Morgan DA, Waish SA, Mark AL, Sivitz WI. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 1997;100:270-8.
16. Leyva F, Godsland IF, Ghatei M, Proudler AJ, Aldis S, Walton Ch, et al. Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Arterioscler Thromb Vasc Biol 1998;18:928-33.
17. Hamilton BS, Paglia D, Kwan AYM, Deitel M. Increased obese mRNA expression in omental fat cell from massively obese humans. Nature Med 1995;1:953-6.
18. Maffei M, Halaas J, Ravussin E. Leptin levels in human and rodents: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjets. Nature Med 1995;1:1155-61.
19. Lönnqvist F, Amer P, Nordfors L, Schalling M. Over-expression of the obese (ob) gene in adipose tissue of human obese subjects. Nature Med 1995;1:950-3.
20. Segal KR, Landt M, Klein S. Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes 1996;45:988-91.
21. Agata J, Masuda A, Takada M, Higahiura K, Murakami H, Miyazaki Y, et al. High plasma immunoreactive leptin level in essential hypertension. Am J Hypertens 1997;10:1171-4.
22. Dante A, Paniagua S. Prevalencia de insuficiencia renal crónica en la población derechohabiente del Instituto Mexicano del Seguro Social. En: García PMC, Reyes MH, Viniegra VL, editores. Las múltiples facetas de la investigación en salud: proyectos estratégicos del Instituto Mexicano del Seguro Social. México: Sestante, 2001; p. 153-70.
23. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Arch Inter Med 1997;157:2413-46.
24. Norma Oficial Mexicana NOM-174-11998, para el Manejo Integral de la Obesidad. Diario Oficial de la Federación México. Rev Med IMSS 2000;38:397-403.
25. National Cholesterol Education Program. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Bethesda: National Heart, Lung, and Blood Institute, 2002. NIH Publication N.° 01-3670. May 2001. JAMA 2001;285:248697.
26. Ma Zhongmin, Gingerich RL, Santiago JV, Klein S, Smith CH, Land M. Radioimmunoassay of leptin in human plasma. Clin Chem 1996;42:942-6.
27. Pfeifer MA, Halter JB, Porte D Jr. Insulin secretion in diabetes mellitus. Am J Med 1981;70:579-88.
28. Murakami T, Shima K. Cloning of rat obese cDNA and its expression in obese rats. Biochem Biophys Res Comm 1995;209:944-2.
29. Maffei M, Fei H, Lee GH. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc Natl Acad Sci USA 1995;92:6957-60.
30. Kissebah AH, Krakower GR. Regional adiposity and mortality. Physiol Rev 1994;74:761-811.
31. Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, et al. Acute and chronic effect of insulin on leptin production in humans. Diabetes 1996;45:699-701.
32. Muller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizumo TM, Warden CH, et. al. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 1998;139:551-8.
33. Schwatz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, et al. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 1996;45:531-8.
34. Shek EW, Brands MW, Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension 1998;31:409-14.
35. Hodge AM, Boyko EJ, De Courten M, Zimmet PZ, Chitson P, Tuomilehto J, et al. Leptin and other components of the metabolic syndrome in Mauritus - a factor analysis. Int J Obes Relat Metab Disord 2001;25:126-31.