-
1
-
-
0031459844
-
Mechanisms of progression in autosomal dominant polycystic kidney disease
-
GRANTHAM JJ: Mechanisms of progression in autosomal dominant polycystic kidney disease. Kidney Int (Suppl 63):S93-S97, 1997
-
(1997)
Kidney Int
, Issue.SUPPL. 63
-
-
Grantham, J.J.1
-
2
-
-
0035083551
-
The genetics and physiology of polycystic kidney disease
-
CALVET JP, GRANTHAM JJ: The genetics and physiology of polycystic kidney disease. Semin Nephrol 21:107-123, 2001
-
(2001)
Semin Nephrol
, vol.21
, pp. 107-123
-
-
Calvet, J.P.1
Grantham, J.J.2
-
3
-
-
0036707893
-
Genetics and pathogenesis of polycystic kidney disease
-
IGARASHI P, SOMLO S: Genetics and pathogenesis of polycystic kidney disease. J Am Soc Nephrol 13:2384-2398, 2002
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2384-2398
-
-
Igarashi, P.1
Somlo, S.2
-
4
-
-
0028278058
-
The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16
-
THE EUROPEAN POLYCYSTIC KIDNEY DISEASE CONSORTIUM: The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. Cell 77:881-894, 1994
-
(1994)
Cell
, vol.77
, pp. 881-894
-
-
-
5
-
-
0028942745
-
Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PDK1) gene predicts the presence of a leucine-rich repeat
-
THE AMERICAN PKD1 CONSORTIUM: Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PDK1) gene predicts the presence of a leucine-rich repeat. Hum Mol Genet 4:575-582, 1995
-
(1995)
Hum Mol Genet
, vol.4
, pp. 575-582
-
-
-
6
-
-
0029002967
-
Polycystic kidney disease: The complete structure of the PKD1 gene and its protein
-
THE INTERNATIONAL POLYCYSTIC KIDNEY DISEASE CONSORTIUM: Polycystic kidney disease: The complete structure of the PKD1 gene and its protein. Cell 8:289-298, 1995
-
(1995)
Cell
, vol.8
, pp. 289-298
-
-
-
7
-
-
15844385078
-
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
-
MOCHIZUKI T, WU G, HAYASHI T, et al: PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272:1339-1342, 1996
-
(1996)
Science
, vol.272
, pp. 1339-1342
-
-
Mochizuki, T.1
Wu, G.2
Hayashi, T.3
-
8
-
-
18344366124
-
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin transcription factor domain and parallel beta-helix 1 repeats
-
ONUCHIC LF, FURU L, NAGASAWA Y, et al: PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin transcription factor domain and parallel beta-helix 1 repeats. Am J Hum Genet 70:1305-1317, 2002
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1305-1317
-
-
Onuchic, L.F.1
Furu, L.2
Nagasawa, Y.3
-
9
-
-
0036509712
-
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
-
WARD CJ, HOGAN MC, ROSSETTI S, et al: The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 30:259-269, 2002
-
(2002)
Nat Genet
, vol.30
, pp. 259-269
-
-
Ward, C.J.1
Hogan, M.C.2
Rossetti, S.3
-
10
-
-
0030463257
-
Murine models of polycystic kidney disease
-
SCHIEREN G, PEY R, BACH J, et al: Murine models of polycystic kidney disease. Nephrol Dial Transplant 11 (Suppl 6):38-45, 1996
-
(1996)
Nephrol Dial Transplant
, vol.11
, Issue.SUPPL. 6
, pp. 38-45
-
-
Schieren, G.1
Pey, R.2
Bach, J.3
-
11
-
-
0023795612
-
Autosomal recessive polycystic kidney disease in a murine model. A gross and microscopic description
-
GATTONE VH 2nd, CALVET JP, COWLEY BD JR., et al: Autosomal recessive polycystic kidney disease in a murine model. A gross and microscopic description. Lab Invest 59:231-238, 1988
-
(1988)
Lab Invest
, vol.59
, pp. 231-238
-
-
Gattone II, V.H.1
Calvet, J.P.2
Cowley Jr., B.D.3
-
12
-
-
0036177603
-
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
-
HOU X, MRUQ M, YODER BK, et al: Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest 109:533-540, 2002
-
(2002)
J Clin Invest
, vol.109
, pp. 533-540
-
-
Hou, X.1
Mruq, M.2
Yoder, B.K.3
-
13
-
-
0031252295
-
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
-
LU W, PEISSEL B, BABAKHANLOU H, et al: Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet 17:179-181, 1997
-
(1997)
Nat Genet
, vol.17
, pp. 179-181
-
-
Lu, W.1
Peissel, B.2
Babakhanlou, H.3
-
14
-
-
0032540226
-
Somatic inactivation of Pkd2 results in polycystic kidney disease
-
WU G, D'AGATI V, CAI Y, et al: Somatic inactivation of Pkd2 results in polycystic kidney disease. Cell 93:177-188, 1998
-
(1998)
Cell
, vol.93
, pp. 177-188
-
-
Wu, G.1
D'agati, V.2
Cai, Y.3
-
15
-
-
0032909095
-
Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes
-
LU W, FAN X, BASORA N, et al: Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes. Nat Genet 21:160-161, 1999
-
(1999)
Nat Genet
, vol.21
, pp. 160-161
-
-
Lu, W.1
Fan, X.2
Basora, N.3
-
16
-
-
0034652247
-
Polycystin 1 is required for the structural integrity of blood vessels
-
KIM K, DRUMMOND I, IBRAGHIMOV-BESKROVNAYA O, et al: Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci USA 97:1731-1736, 2000
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1731-1736
-
-
Kim, K.1
Drummond, I.2
Ibraghimov-Beskrovnaya, O.3
-
17
-
-
0035834136
-
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
-
BOULTER C, MULROY S, WEBB S, et al: Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene. Proc Natl Acad Sci USA 98:12174-12179, 2001
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12174-12179
-
-
Boulter, C.1
Mulroy, S.2
Webb, S.3
-
18
-
-
0036785149
-
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
-
YODER BK, HOU X, GUAY-WOODFORD LM: The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 13:2508-2516, 2002
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2508-2516
-
-
Yoder, B.K.1
Hou, X.2
Guay-Woodford, L.M.3
-
19
-
-
0037884961
-
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
-
LIN F, HIESBERGER T, CORDES K, et al: Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 100:5286-5291, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5286-5291
-
-
Lin, F.1
Hiesberger, T.2
Cordes, K.3
-
20
-
-
0029810450
-
Expression of a cut-related homeobox gene in developing and polycystic mouse kidney
-
VANDEN HEUVEL GB, BOOMER R, MCCONNELL KR, et al: Expression of a cut-related homeobox gene in developing and polycystic mouse kidney. Kidney Int 50:453-461, 1996
-
(1996)
Kidney Int
, vol.50
, pp. 453-461
-
-
Vanden Heuvel, G.B.1
Boomer, R.2
McConnell, K.R.3
-
21
-
-
0032541492
-
The mammalian cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase
-
COQUERET O, BERUBE G, NEPVEU A: The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase. EMBO J 17:4680-4694, 1998
-
(1998)
EMBO J
, vol.17
, pp. 4680-4694
-
-
Coqueret, O.1
Berube, G.2
Nepveu, A.3
-
22
-
-
0036569798
-
Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in down-regulation of p27 (kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia
-
LEDFORD AW, BRANTLEY JG, KEMENY G, et al: Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in down-regulation of p27 (kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia. Dev Biol 245:157-171, 2002
-
(2002)
Dev Biol
, vol.245
, pp. 157-171
-
-
Ledford, A.W.1
Brantley, J.G.2
Kemeny, G.3
-
23
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
-
FERO ML, RIVKIN M, TASCH M, et al: A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 85:733-744, 1996
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
-
24
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
KIYOKAWA H, KINEMAN RD, MANOVA-TODOROVA KO, et al: Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 85:721-732, 1996
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
-
25
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
NAKAYAMA K, ISHIDA N, SHIRANE M, et al: Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720, 1996
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
-
27
-
-
0037133954
-
PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
-
BHUNIA AK, PIONTEK K, BOLETTA A, et al: PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 109:157-168, 2002
-
(2002)
Cell
, vol.109
, pp. 157-168
-
-
Bhunia, A.K.1
Piontek, K.2
Boletta, A.3
-
28
-
-
0035504102
-
Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
-
LU W, SHEN X, PAVLOVA A, et al: Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects. Hum Mol Genet 10:2385-2396, 2001
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2385-2396
-
-
Lu, W.1
Shen, X.2
Pavlova, A.3
-
29
-
-
0029787158
-
A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis
-
VANDEN HEUVEL GB, QUAGGIN SE, IGARASHI P: A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis. Biol Reprod 55:731-739, 1996.
-
(1996)
Biol Reprod
, vol.55
, pp. 731-739
-
-
Vanden Heuvel, G.B.1
Quaggin, S.E.2
Igarashi, P.3
-
30
-
-
0037378488
-
Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis
-
BRANTLEY JG, SHARMA M, ALCALAY NI, VANDEN HEUVEL GB: Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis. Kidney Int 63:1240-1248, 2003
-
(2003)
Kidney Int
, vol.63
, pp. 1240-1248
-
-
Brantley, J.G.1
Sharma, M.2
Alcalay, N.I.3
Vanden Heuvel, G.B.4
-
32
-
-
0033038906
-
Differential changes of cell cycle regulators and activities in kidneys during pre- and postnatal development
-
PARK SK, KIM W, LEE H, et al: Differential changes of cell cycle regulators and activities in kidneys during pre- and postnatal development. Nephron 81:334-341, 1999
-
(1999)
Nephron
, vol.81
, pp. 334-341
-
-
Park, S.K.1
Kim, W.2
Lee, H.3
-
33
-
-
0029805189
-
Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD)
-
LANOIX J, D'AGATI V, SZABOLCS M, TRUDEL M: Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD). Oncogene 13:1153-1160, 1996
-
(1996)
Oncogene
, vol.13
, pp. 1153-1160
-
-
Lanoix, J.1
D'agati, V.2
Szabolcs, M.3
Trudel, M.4
-
34
-
-
0029035757
-
Apoptosis and loss of renal tissue in polycystic kidney diseases
-
WOO D: Apoptosis and loss of renal tissue in polycystic kidney diseases. N Engl J Med 333:18-25, 1995
-
(1995)
N Engl J Med
, vol.333
, pp. 18-25
-
-
Woo, D.1
-
35
-
-
0030034551
-
Deregulation of cell survival in cystic and dysplastic renal development
-
WINYARD PJ, NAUTA J, LIRENMAN DS, et al: Deregulation of cell survival in cystic and dysplastic renal development. Kidney Int 49:135-146, 1996
-
(1996)
Kidney Int
, vol.49
, pp. 135-146
-
-
Winyard, P.J.1
Nauta, J.2
Lirenman, D.S.3
-
36
-
-
0036408651
-
Multiorgan mRNA misexpression in murine autosomal recessive polycystic kidney disease
-
GATTONE VH, RICKER JL, TRAMBAUGH CM, KLEIN RM: Multiorgan mRNA misexpression in murine autosomal recessive polycystic kidney disease. Kidney Int 62:1560-1569, 2002
-
(2002)
Kidney Int
, vol.62
, pp. 1560-1569
-
-
Gattone, V.H.1
Ricker, J.L.2
Trambaugh, C.M.3
Klein, R.M.4
|