Novel function of metallothionein in photoprotection: Metallothionein- null mouse exhibits reduced tolerance against ultraviolet B injury in the skin

Journal of Investigative Dermatology

Volumn 111, Issue 4, 1998, Pages 582-585

  Hanada, Katsumi ^a   Sawamura, Daisuke ^a   Tamai, Katsuto ^a   Baba, Takako ^a   Hashimoto, Isao ^a   Muramatsu, Tsutomu ^b   Miura, Nobuhiko ^c   Naganuma, Akira ^c  

^a HIROSAKI UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Apoptosis; Knockout mouse; Sunburn cell

Indexed keywords

CADMIUM CHLORIDE; GLUTATHIONE; METALLOTHIONEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; GLUTATHIONE METABOLISM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOCKOUT MOUSE; MALE; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; SKIN CULTURE; SKIN PROTECTION; SOLAR RADIATION; ULTRAVIOLET B RADIATION;

EID: 0031716179     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00342.x     Document Type: Article

References (31)

1. Baba T, Hanada K, Hashimoto I: The study of ultraviolet B-induced apoptosis in cultured mouse keratinocytes and in mouse skin. J Dermatol Sci 12:18-23, 1996
2. Bissett DL, Chatterjee R, Hannon DP: Photoprotective effect of superoxide, scavenging antioxidants against ultraviolet radiation-induced chronic skin damage in the hairless mouse. Photoderm Photoimmunol Photomed 7:56-62, 1990
3. Bobrow MN, Harris TD, Shaughnessy KJ, Litt GJ: Catalyzed reporter deposition, a novel method of signal amplification: application to immunoassays. J Immunol Meth 125:279-285, 1989
4. Brenner W, Gshnait F: Decreased DNA repair activity in sunburn cells. A possible pathogenetic factor of the epidermal sunburn reaction. Arch Dermatol Res 266:11-16, 1979
5. Danno K, Takigawa M, Horio T: Relationship of the cell cycle to sunburn cell formation. Photohem Photobiol 34:203-206, 1981
6. Danno K, Horio T, Taldgawa M, Immura S: Role of oxygen intermediates in UV-induced epidermal cell injury. J Invest Dermatol 83:166-168, 1984
7. Darr D, Combs S, Dunston S, Manning T, Pinnel S: Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage. Br J Dermatol 127:247-253, 1992
8. Gniadecki R, Hansen MR, Wulf HG: Two pathways for induction of apoptosis by ultraviolet radiation in cultured human keratinocytes. J Invest Dermatol 109:163-169, 1997
9. Griffith OW, Meister A: Translocation of intracellular glutathione to membrane-bound r-glutamyl transpeptidase as a discrete step in the γ-glutamyl cycle: glutathionuria after inhibition of transpeptidase. Proc. Natl Acad Sci USA 76:268-272, 1976
10. Hamer DH: Metallothionein. Ann Rev Biochem 55:913-951, 1986
11. Hanada K, Gange RW, Siebert E, Hassan T: Protective effects of cadmium chloride against UVB injury in mouse skin and in cultured human cells: a possible role of cadmium-induced metallothionein. Photodermatol Photoimmunol Photomed 8:111-115, 1991
12. Hanada K, Baba T, Hashimoto I, Fukui R, Watanabe S: Possible role of cutaneous metallothionein in protection against photo-oxidative stress: epidermal localization and scavenging activity for superoxide and hydroxyl radicals. Photodermatol Photoimmunol Photomed 9:209-213, 1993
13. Hanada K, Sawamura P, Tamai K, Hashimoto I, Kobayashi S: Photoprotective effect ofesterified glutathione against ultraviolet B-induced sunburn cell formation in the hairless mice. J Invest Dermatol 108:727-730, 1997
14. Hockenbery DM, Oltavai ZN, Yin XM, Milliman CL, Korsineyer W: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251, 1993
15. Iwata S, Hori T, Sato N, et al: Adult T-cell leukemia (ATQ-derived factor human thioredoxin prevents apoptosis of lymohoid cells induced by I-cysteine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state. J Immunol 158:3108-3117, 1997
16. Kane KS, Maytin EV: Ultraviolet B-induced apoptosis of keratinocytes in murine skin is reduced by mild local hyperthermia. J Invest Dermatol 104:62-67, 1995
17. Kerr JFR, Wyllie AH: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
18. Lafon-Cazal M, Pietri S, Culcasi M, Bokhaert J: NMDA-dependent superoxide production and neurotoxicity. Nature 364:535-537, 1993
19. Masters BA, Kelley EJ, Quaife CJ, Brinster RL: Targeted disruption of metallothionein I and Il genes increases sensitivity to cadmium. Proc Natl Acad Sci USA 91:584-588, 1994
20. Mathews-Roth MM: Carotenoids quench evolution of excited species in epidermis exposed to UV-B (290-320 nm) light. Photochem Photobiol 43:91-93, 1986
21. Michalska. A, Choo KHA: Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Natl Acad Sci USA 90:8088-8092, 1993
22. Miyachi Y, Horio T, Imamura S: Sunburn cell formation is prevented by scavenging oxygen intermediates. Clin Exp Dermatol 8:305-310, 1983
23. Muramatsu T, Tada H, Kobayashi H, Yaniji M, Shirat T, Ohnishi T: Induction of the 72-W heat shock protein in organ-cultured normal human skin. J Invest Dermatol 98:786-790, 1992
24. Naganuma A, Satoh M, Imura N: Prevention of lethal and renal toxicity of cis-diaminedichloroplatinum (II) by induction of metallothionein synthesis without compromising its antitumor activity in mice. Cancer Res 47:983-987, 1987
25. Oguira R, Sugiyarna M, Nishi J, Haramaki N: Mechanism of lipid radical formation following exposure of epidermal homogenate to ultraviolet light. J Invest Dermatol 97:1044-1047, 1991
26. Parat MO, Richard MJ, Pollet S, Hadjur C, Fvier A, Beani JC: Zinc and DNA fragmentation in keratinocyte apoptosis: its inhibitory effect in UVB irradiated cells. Photochem Photobiol B 37:101-106, 1997
27. Quaife G, Findley SD, Erickson JC, Froelick GJ, Kelly EJ, Zambrowicz BP, Palmiter RD: Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry 33:7250-7259, 1994
28. Sarafian TA, Bredesen DE: Invited commentary: Is apoptosis mediated by reactive oxygen species? Free Rad Res Commun 21:1-8, 1994
29. Schwart A, Bhardwaj R, Aragane Y, et al: Ultraviolet B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-cc in the formation of sunburn cells. J Invest Dermatol 104:922-927, 1995
30. Shitraishi N, Aona A, Utsumi K: Increased metallothionein content in liver induced by X-irradiation and exposure to high oxygen tension. Radiat Res 95:2958-2302, 1983
31. Thornalley PJ, Vasak M: Possible role of metallothionein protein against radiation-induced oxidative stress, kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochem Biophys Acta 827, Year?