Monitoring HSVtk suicide gene therapy: The role of [18F]FHPG membrane transport

British Journal of Cancer

Volumn 91, Issue 12, 2004, Pages 2079-2085

  Buursma, A R ^a   Van Dillen, I J ^a   Van Waarde, A ^a   Vaalburg, W ^a   Hospers, G A P ^a   Mulder, N H ^a   De Vries, E F J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Acyclovir; Ganciclovin 18F FHPG; Gene therapy; Herpes simplex virus thymidine kinase; Membrane transport; Positron emission tomography

Indexed keywords

2 CHLOROADENOSINE; 9 [(3 FLUORO 1 HYDROXY 2 PROPOXY)METHYL]GUANINE F 18; ACICLOVIR; ADENINE; CARRIER PROTEIN; DIPYRIDAMOLE; GANCICLOVIR; NITROBENZYLTHIOINOSINE; NUCLEIC ACID BASE; NUCLEOBASE TRANSPORTER; NUCLEOSIDE TRANSPORTER; PRODRUG; PROTEIN INHIBITOR; THYMIDINE; THYMIDINE KINASE; THYMINE; TRACER; UNCLASSIFIED DRUG; URIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD SAMPLING; CELL LEVEL; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DRUG TISSUE LEVEL; DRUG TRANSPORT; DRUG UPTAKE; ENZYME ASSAY; ENZYME INHIBITION; FEMALE; GLIOMA CELL; HERPES SIMPLEX VIRUS 1; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHARMACOKINETICS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SUICIDE GENE THERAPY; TECHNIQUE; TRANSPORT KINETICS; TUMOR MODEL;

ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; FLUORINE RADIOISOTOPES; GANCICLOVIR; GENE THERAPY; GENES, TRANSGENIC, SUICIDE; GLIOMA; HERPESVIRUS 1, HUMAN; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RATS; THYMIDINE KINASE;

EID: 12344256916     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602216     Document Type: Article

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