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Volumn 10, Issue 3, 2002, Pages 525-530

Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase

(7) Murray, Paul E a McNally, Virginia A a Lockyer, Stacey D a Williams, Kaye J a Stratford, Ian J a Jaffar, Mohammed a Freeman, Sally a

a UNIVERSITY OF MANCHESTER (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DIHYDROXYPYRIMIDIN 6 YL)PYRIDINIUM CHLORIDE; 1 (5 BROMO 2,4 DIHYDROXYPYRIMIDIN 6 YL)PYRIDINIUM CHLORIDE; 1 (5 CHLORO 2,4 DIHYDROXYPYRIMIDIN 6 YL)PYRIDINIUM CHLORIDE; 1 [(2,4 DIHYDROXY 5 METHYLPYRIMIDIN 1 YL)METHYL]PYRIDINIUM CHLORIDE; 1 [(2,4 DIHYDROXY 5 METHYLPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 1 [(2,4 DIHYDROXYPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 1 [(5 BROMO 2,4 DIHYDROXYPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 1 [(5 CHLORO 2,4 DIHYDROXYPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 1 [2 (2,4 DIHYDROXY 5 METHYLPYRIMIDIN 1 YL)ETHYL]PYRIDINIUM BROMIDE; 2 AMINO 1 [(5 CHLORO 2,4 DIHYDROXYPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 3 AMINO 1 [(5 CHLORO 2,4 DIHYDROXYPYRIMIDIN 6 YL)METHYL]PYRIDINIUM CHLORIDE; 6 AMINO 5 BROMOURACIL; PYRIDINIUM DERIVATIVE; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG; URACIL DERIVATIVE; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; URACIL;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; IC 50; NONHUMAN; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; DRUG ANTAGONISM; ENZYMOLOGY; NEOVASCULARIZATION (PATHOLOGY); SOLUBILITY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; ESCHERICHIA COLI; INHIBITORY CONCENTRATION 50; NEOVASCULARIZATION, PATHOLOGIC; PYRIDINIUM COMPOUNDS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; THYMIDINE PHOSPHORYLASE; URACIL;

EID: 0036152769 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00309-1 Document Type: Article

Times cited : (31)

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