Effects of chronic intrathecal infusion of a ∂ opioid agonist in dogs

Toxicological Sciences

Volumn 71, Issue 2, 2003, Pages 263-275

  Horais, Kjersti ^a   Hruby, Victor ^b   Rossi, Steven ^a   Cizkova, Dasa ^a   Meschter, Carol ^c   Dorr, Robert ^d   Yaksh, Tony L ^a  

^a University of California   (United States)

^b University of Arizona   (United States)

^c Veterinary Pathology   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

Author keywords

opioid agonist; Dog; DPDPE; Granuloma; Intrathecal

Indexed keywords

DELTA OPIATE RECEPTOR AGONIST; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BOLUS INJECTION; CATHETER; CELL INFILTRATION; CEREBROSPINAL FLUID ANALYSIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE SEVERITY; DOG; DOSE TIME EFFECT RELATION; DRUG CLEARANCE; DRUG INFUSION; FIBROSIS; GRANULOCYTE; GRANULOMA; HISTOPATHOLOGY; LEG; LONG TERM EXPOSURE; MACROPHAGE; MONOCYTE; NECROSIS; NEUROTOXICITY; NEUTROPHIL; NONHUMAN; REVIEW; SPINAL CORD; STEADY STATE; TISSUE REACTION;

ANALGESICS, OPIOID; ANIMALS; AREA UNDER CURVE; BEHAVIOR, ANIMAL; CATHETERS, INDWELLING; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, D-PENICILLAMINE (2,5)-; FEMALE; GRANULOMA; INJECTIONS, SPINAL; MALE; MOTOR ACTIVITY; SPINAL CORD; SPINAL CORD DISEASES;

ANIMALIA; CANIS FAMILIARIS;

EID: 12244298897     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/71.2.263     Document Type: Review

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