Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: A possible gene-environment interaction for autoimmunity

Journal of Rheumatology

Volumn 30, Issue 2, 2003, Pages 276-282

  Fraser, Patricia A ^g   Ding, Wei Zi ^h   Mohseni, Mehrdad ^a   Treadwell, Edward L ^b   Dooley, Mary Anne ^c   St Clair, E William ^d   Gilkeson, Gary S ^e   Cooper, Glinda S ^f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^g CENTER FOR BLOOD RESEARCH   (United States)

^h NONE

Author keywords

Autoimmune disease; Glutathione S transferase; Metabolism; Systematic lupus erythematosus; Ultraviolet radiation

Indexed keywords

AUTOANTIBODY; DNA; GLUTATHIONE TRANSFERASE; REACTIVE OXYGEN METABOLITE;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE INTERACTION; GENOTYPE; HEREDITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; METABOLISM; NULL ALLELE; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; SUN EXPOSURE; SYSTEMIC LUPUS ERYTHEMATOSUS; ULTRAVIOLET RADIATION;

ADULT; AUTOANTIBODIES; AUTOIMMUNITY; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HOMOZYGOTE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; OCCUPATIONAL EXPOSURE; RISK FACTORS; SUNLIGHT; ULTRAVIOLET RAYS;

EID: 12244253788     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Lu L, Kaliyaperumal A, Boumpas DT, Datta SK. Major peptide autoepitopes for nucleosome-specific T cells of human lupus. J Clin Invest 1999;104:345-55.
2. Mohan C, Adams S, Stanik V, Datta SK. Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J Exp Med 1993;177:1367-81.
3. Burlingame RW, Boey ML, Starkebaum G, Rubin RL. The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus. J Clin Invest 1994;94:184-92.
4. Hayes JD, Strange RC. Glutathione-S-transferase polymorphisms and their biological consequences. Pharmacology 2000;61:154-66.
5. Watson M, Steward R, Smith G, Massey T, Bell D. Glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis 1998;19:275-80.
6. Landi S, Norppa H, Frenzilli G, et al. Individual sensitivity to cytogenetic effect of 1,2:3,4 - diepoxybutane in cultured human lymphocytes: influence of glutathione S-transferase M1, P1 and T1 genotypes. Pharmacogenetics 1998;8:461-71.
7. Ollikainen T, Hirvonen A, Norppa H. Influence of GSTT1 genotype on sister chromatid exchange induction by styrene-7,8-oxide in cultured human lymphocytes. Environ Mol Mutagen 1998; 31:311-5.
8. Xu X, Wiencke JK, Niu T, et al. Benzene exposure, glutathione S-transferase theta homozygous deletion, and sister chromatid exchanges. Am J Ind Med 1998;33:157-63.
9. Park JY, Schantz SP, Stem JC, Kaur T, Lazarus P. Association between glutathione S-transferase p polymorphisms and oral cancer risk. Pharmacogenetics 1999;9:497-504.
10. Shinka T, Ogura H, Morita T, Nishikawa T, Fuginaga T, Ohkawa T. Relationship between glutathione S-transferase M1 deficiency and urothelial cancer in dye workers exposed to aromatic amines. J Urol 1998;159:380-3.
11. Olshan AF, Weissler MC, Watson MA, Bell DA. GSTM1, GSTT1, GSTP1, CYP1A1, and NAT1 polymorphisms, tobacco use, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev 2000;9:185-91.
12. Millikan R, Pittman G, Tse C-K, Savitz DA, Newman B, Bell D. Gluathione S-transferases M1, T1, and P1 and breast cancer. Cancer Epidemiol Biomarkers Prev 2000;9:567-73.
13. Ollier W, Davies E, Snowden N, et al. Association of homozygosity for glutathione-S-transferase GSTM1 null alleles with the Ro+/Laautoantibody profile in patients with systemic lupus erythematosus. Arthritis Rheum 1996;39:1763-4.
14. Tew MB, Ahn CW, Friedman AW, et al. Systemic lupus erythematosus in three ethnic groups. VIII. Lack of association of glutathione S-transferase null alleles with disease manifestations. Arthritis Rheum 2001;44:981-3.
15. Griffiths HR, Mistry P, Herbert KE, Lunec J. Molecular and cellular effects of ultraviolet light-induced genotoxicity. Crit Rev Clin Lab Sci 1998;35:189-237.
16. Muller L, Kasper P, Kersten B, Zhang J. Photochemical genotoxicity and photochemical carcinogenesis - two sides of a coin? Toxicol Lett 1998;102-3:383-7.
17. Record IR, Jannes M, Dreosti IE. Protection by zinc against UVA-and UVB-induced cellular and genomic damage in vivo and in vitro. Biol Trace Elem Res 1996;53:19-25.
18. Runger TM, Epe B, Moller K. Processing of directly and indirectly ultraviolet-induced DNA damage in human cells. Recent Results Cancer Res 1995;139:31-42.
19. Nived O, Johansen PB, Sturfelt G. Standardized ultraviolet-A exposure provokes skin reaction in systemic lupus erythematosus. Lupus 1993;2:247-50.
20. Nived O, Sturfelt G, Ryberg B. Two UV-induced episodes of myelitis in a patient with systemic lupus erythematosus. J Intern Med 1992;232:461-3.
21. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
22. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
23. Cooper GS, Dooley MA, Treadwell EL, St. Clair EW, Gilkeson GS. Hormonal and reproductive risk factors for development of systemic lupus erythematosus. Arthritis Rheum 2002;46:1830-9.
24. Cooper GS, Parks CG, Treadwell EL, et al. Differences by race, sex, and age in the clinical and immunologic features of recently-diagnosed systemic lupus erythematosus patients in the Southeastern United States. Lupus 2002;11:161-7.
25. Chen CL, Liu Q, Relling MV. Simultaneous characterization of glutathione S-transferase M1 and T1 polymorphisms by polymerase chain reaction in American whites and blacks. Pharmacogenetics 1996;6:187-91.
26. Nedelcheva KV, Andersen TI, Erikstein B, et al. Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients. Pharmacogenetics 1998;8:441-7.
27. Cooper GS, Dooley MA, Treadwell EL, St. Clair EW, Parks CG, Gilkeson GS. Hormonal, environmental, and infectious disease risk factors for the development of systemic lupus erythematosus. Arthritis Rheum 1998;41:1714-24.
28. Berardesca E, Maibach H. Racial differences in skin pathophysiology. J Am Acad Dermatol 1996;34:667-72.
29. Gilchrest BA, Eller MS. DNA photodamage stimulates melanogenesis and other photoprotective responses. J Invest Dermatol Symp Proc 1999;4:35-40.
30. Shono S, Imura M, Ota M, Ono S, Toda K. The relationship of skin color, UVB-induced erythema, and melanogenesis. J Invest Dermatol 1985;84:265-7.
31. Casciola-Rosen L, Rosen A. Ultraviolet light-induced keratinocyte apoptosis: a potential mechanism for the induction of skin lesions and autoantibody production in LE. Lupus 1997;6:175-80.
32. Rosen A, Casciola-Rosen L. Clearing the way to mechanisms of autoimmunity. Nature Med 2001;7:664-5.
33. Golan T, Elkon K, Ghatavi A, Krueger J. Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus. J Clin Invest 1992;90:1067-76.
34. English DR, Armstrong BK, Kricker A. Reproducibility of reported measurements of sun exposure in a case-control study. Cancer Epidemiol Biomarkers Prev 1998;7:857-63.
35. Moehrle M, Garbe C. Personal UV dosimetry by Bacillus subtilis spore films. Dermatology 2000;200:1-5.
36. Heenen M, Giacomoni PU, Golstein P. Individual variations in the correlation between erythemal threshold, UV-induced DNA damage and sun-burn cell formation. J Photochem Photobiol B 2001; 63:84-7.
37. Marrot L, Belaidi JP, Chaubo C, Meunier JR, Perez P, Agapakis-Causse C. An in vitro strategy to evaluate the phototoxicity of solar UV at the molecular and cellular level: application to photoprotection assessment. Eur J Dermatol 1998;8:403-12.