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Volumn 6, Issue 2, 1997, Pages 175-180

Ultraviolet light-induced keratinocyte apoptosis: A potential mechanism for the induction of skin lesions and autoantibody production in LE

Author keywords

Apoptosis; Autoantibody; ICE; Keratinocytes; Lupus

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN;

EID: 0031046862     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/096120339700600213     Document Type: Article
Times cited : (155)

References (52)
  • 1
    • 0026352088 scopus 로고
    • Lupus erythematosus in the 1980s: A survey of 570 patients
    • Pistiner M et al. Lupus erythematosus in the 1980s: A survey of 570 patients. Semin Arthitis Rheum 1991; 21: 55-64.
    • (1991) Semin Arthitis Rheum , vol.21 , pp. 55-64
    • Pistiner, M.1
  • 2
    • 0022988494 scopus 로고
    • Systemic lupus erythematosus clinical issues
    • Stevens MB. Systemic lupus erythematosus clinical issues. Springer Semin Immunopathol 1986; 9: 251-270.
    • (1986) Springer Semin Immunopathol , vol.9 , pp. 251-270
    • Stevens, M.B.1
  • 3
    • 0028292951 scopus 로고
    • Genetic and structural evidence for antigen selection of anti-DNA antibodies
    • Radic MZ, Weigert M. Genetic and structural evidence for antigen selection of anti-DNA antibodies. Ann Rev Immunol 1994, 12: 487-520.
    • (1994) Ann Rev Immunol , vol.12 , pp. 487-520
    • Radic, M.Z.1    Weigert, M.2
  • 4
    • 0026750095 scopus 로고
    • The role of somatic mutation in the pathogenic anti-DNA response
    • Diamond et al. The role of somatic mutation in the pathogenic anti-DNA response. Ann Rev Immunol 1992; 10: 731-757.
    • (1992) Ann Rev Immunol , vol.10 , pp. 731-757
    • Diamond1
  • 5
    • 0027407108 scopus 로고
    • Dominance and crypticity of T cell antigenic determinants
    • Sercarz EE et al. Dominance and crypticity of T cell antigenic determinants. Ann Rev Immunol 1993; 11: 729-766.
    • (1993) Ann Rev Immunol , vol.11 , pp. 729-766
    • Sercarz, E.E.1
  • 6
    • 0029006389 scopus 로고
    • How can cryptic epitopes trigger autoimmunity?
    • Lanzavecchia A. How can cryptic epitopes trigger autoimmunity? J Exp Med 1995; 181: 1945-1948.
    • (1995) J Exp Med , vol.181 , pp. 1945-1948
    • Lanzavecchia, A.1
  • 7
    • 0024428816 scopus 로고
    • How some T cells escape tolerance induction
    • Gammon G, Sercarz EE. How some T cells escape tolerance induction. Nature 1989; 342: 183-185.
    • (1989) Nature , vol.342 , pp. 183-185
    • Gammon, G.1    Sercarz, E.E.2
  • 8
    • 0027479452 scopus 로고
    • The inability to process a self-peptide allows autoreactive T cells to escape tolerance
    • Mamula MJ. The inability to process a self-peptide allows autoreactive T cells to escape tolerance. J Exp Med 1993; 177: 567-571.
    • (1993) J Exp Med , vol.177 , pp. 567-571
    • Mamula, M.J.1
  • 9
    • 0028908106 scopus 로고    scopus 로고
    • Self-peptides in the initiation of lupus autoimmunity
    • Bockenstedt LK, Gee RJ, Mamula MJ. Self-peptides in the initiation of lupus autoimmunity. J Immunol 154; 154: 3516-3524.
    • J Immunol 154 , vol.154 , pp. 3516-3524
    • Bockenstedt, L.K.1    Gee, R.J.2    Mamula, M.J.3
  • 10
    • 0029069507 scopus 로고
    • HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing
    • Salemi et al. HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing. J Exp Med 1995; 181: 2253-2257.
    • (1995) J Exp Med , vol.181 , pp. 2253-2257
    • Salemi1
  • 11
    • 0027267589 scopus 로고
    • Suppressive effect of an antibody on processing of T ce1l epitopes
    • Watts C, Lanzavecchia A. Suppressive effect of an antibody on processing of T ce1l epitopes. J Exp Med 1993; 178: 1459-1463.
    • (1993) J Exp Med , vol.178 , pp. 1459-1463
    • Watts, C.1    Lanzavecchia, A.2
  • 12
    • 0029035307 scopus 로고
    • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
    • Simitsek PD et al. Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J Exp Med 1995; 181: 1957-1963.
    • (1995) J Exp Med , vol.181 , pp. 1957-1963
    • Simitsek, P.D.1
  • 13
    • 0028881847 scopus 로고
    • DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis
    • Casciola-Rosen LA, Anhalt GJ, Rosen A. DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. J Exp Med 1995; 182: 1625-1634.
    • (1995) J Exp Med , vol.182 , pp. 1625-1634
    • Casciola-Rosen, L.A.1    Anhalt, G.J.2    Rosen, A.3
  • 14
    • 0015898675 scopus 로고
    • Experimental skin lesions in mice resembling systemic lupus erythematosus
    • Natali PG, Tan EM. Experimental skin lesions in mice resembling systemic lupus erythematosus. Arthritis Rheum 1973; 16: 579-589.
    • (1973) Arthritis Rheum , vol.16 , pp. 579-589
    • Natali, P.G.1    Tan, E.M.2
  • 15
    • 0021674540 scopus 로고
    • Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes
    • LeFeber WP et al. Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes. J Clin Invest 1984; 74: 1545-1551.
    • (1984) J Clin Invest , vol.74 , pp. 1545-1551
    • Lefeber, W.P.1
  • 16
    • 0025139120 scopus 로고
    • Binding of antibodies to the extractable nuclear antigens of SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): Implications for the pathogenesis of photosensitive cutaneous lupus
    • Furukawa F, Kashihara-Sawami M, Lyons MB, Norris DA. Binding of antibodies to the extractable nuclear antigens of SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupus. J Invest Dermatol 1990; 94: 77-85.
    • (1990) J Invest Dermatol , vol.94 , pp. 77-85
    • Furukawa, F.1    Kashihara-Sawami, M.2    Lyons, M.B.3    Norris, D.A.4
  • 17
    • 0026779275 scopus 로고
    • Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation
    • Golan TD, Elkon KB, Gharavi AE, Krueger JG. Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation. J Clin Invest 1992; 90: 1067-1076.
    • (1992) J Clin Invest , vol.90 , pp. 1067-1076
    • Golan, T.D.1    Elkon, K.B.2    Gharavi, A.E.3    Krueger, J.G.4
  • 18
    • 0019793706 scopus 로고
    • The lupus band test
    • Provost YT. The lupus band test. Int J Dermatol 1981; 20: 475-481.
    • (1981) Int J Dermatol , vol.20 , pp. 475-481
    • Provost, Y.T.1
  • 19
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179: 1317-1330.
    • (1994) J Exp Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 20
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 21
    • 0029866102 scopus 로고    scopus 로고
    • Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in SLE
    • Casciola-Rosen LA, Rosen A, Petri M, Schlissel M. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in SLE. Proc Natl Acad Sci USA 1996; 93: 1624-1629.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1624-1629
    • Casciola-Rosen, L.A.1    Rosen, A.2    Petri, M.3    Schlissel, M.4
  • 22
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts?
    • Martin SJ, Green DR. Protease activation during apoptosis: Death by a thousand cuts?. Cell 1995; 82: 349-352.
    • (1995) Cell , vol.82 , pp. 349-352
    • Martin, S.J.1    Green, D.R.2
  • 24
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar S. ICE-like proteases in apoptosis. Trends Biochem Sci 1995; 20: 198-202.
    • (1995) Trends Biochem Sci , vol.20 , pp. 198-202
    • Kumar, S.1
  • 25
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to the mammalian interleukin-1 β-converting enzyme
    • Yuan et al. The C. elegans cell death gene ced-3 encodes a protein similar to the mammalian interleukin-1 β-converting enzyme. Cell 1993; 75: 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan1
  • 26
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell 1996; 85: 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 27
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996; 85: 817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1
  • 28
    • 0344053451 scopus 로고    scopus 로고
    • In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
    • Fernandes-Alnemri T et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci USA 1996; 93: 7464-7469.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7464-7469
    • Fernandes-Alnemri, T.1
  • 29
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 β-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 β-converting enzyme. J Biol Chem 1994; 269: 30761-30764.
    • (1994) J Biol Chem , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 30
    • 0028990125 scopus 로고
    • Yama/CPP32b, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari et al. Yama/CPP32b, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995; 81: 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari1
  • 31
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
    • Nicholson DW et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43.
    • (1995) Nature , vol.376 , pp. 37-43
    • Nicholson, D.W.1
  • 32
    • 0029025549 scopus 로고
    • Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family
    • Fernandes-Alnemri T, Litwack G, Alnemri ES. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res 1995; 55: 2737-2742.
    • (1995) Cancer Res , vol.55 , pp. 2737-2742
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 33
    • 0029891838 scopus 로고    scopus 로고
    • The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A
    • Orth K et al. The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A. J Biol Chem 1996; 271: 16443-16446.
    • (1996) J Biol Chem , vol.271 , pp. 16443-16446
    • Orth, K.1
  • 34
    • 0028884167 scopus 로고
    • Mch3, a novel human apoptotic cysteine protease highly related to CPP32
    • Fernandes-Alnemri T et al. Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res 1995; 55: 6045-6052.
    • (1995) Cancer Res , vol.55 , pp. 6045-6052
    • Fernandes-Alnemri, T.1
  • 35
    • 0024470862 scopus 로고
    • Iunduction of endonucleolytic DNA damage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann SH. Iunduction of endonucleolytic DNA damage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 1989; 49: 5870-5878.
    • (1989) Cancer Res , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 36
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly-(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann SH et al. Specific proteolytic cleavage of poly-(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res 1993; 53: 3976-3985.
    • (1993) Cancer Res , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1
  • 37
    • 0027999537 scopus 로고
    • Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death
    • Casciola-Rosen LA, Miller DK, Anhalt GJ, Rosen A. Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. J Biol Chem 1994; 269: 30757-30760.
    • (1994) J Biol Chem , vol.269 , pp. 30757-30760
    • Casciola-Rosen, L.A.1    Miller, D.K.2    Anhalt, G.J.3    Rosen, A.4
  • 38
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • Casciola-Rosen LA et al. Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death. J Exp Med 1996; 183: 1957-1964.
    • (1996) J Exp Med , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.A.1
  • 39
    • 0029046470 scopus 로고
    • Studies of the lamin pioteinase reveal multiple parallel biochemical pathways during apoptotic execution
    • Lazebnik YA et al. Studies of the lamin pioteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci USA 1995; 92: 9042-9046.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9042-9046
    • Lazebnik, Y.A.1
  • 40
    • 0029876247 scopus 로고    scopus 로고
    • Cleavage of actin by interleukin 1β-converting enzyme to reverse DNaseI inhibition
    • Kayalar C. et al. Cleavage of actin by interleukin 1β-converting enzyme to reverse DNaseI inhibition. Proc Natl Acad Sci USA 1996; 93: 2234-2238.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2234-2238
    • Kayalar, C.1
  • 41
    • 0028934919 scopus 로고
    • Proteolysis of fodrin (non-erythroid spectrin) during apoptosis
    • Martin SJ et al. Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem 1995; 270: 6425-6428.
    • (1995) J Biol Chem , vol.270 , pp. 6425-6428
    • Martin, S.J.1
  • 42
    • 0028788309 scopus 로고
    • Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases
    • Brancolini C, Benedetti M, Schneider C. Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases. EMBO J 1995; 14: 5179-5190.
    • (1995) EMBO J , vol.14 , pp. 5179-5190
    • Brancolini, C.1    Benedetti, M.2    Schneider, C.3
  • 43
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis: An interleukin 1 β-converting enzyme-like protease as candidate
    • An B, Dou QP.. Cleavage of retinoblastoma protein during apoptosis: An interleukin 1 β-converting enzyme-like protease as candidate. Cancer Res 1996; 56: 438-442.
    • (1996) Cancer Res , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2
  • 44
    • 13344259987 scopus 로고
    • Proteolytic activation of protein kinase C δ by an ICE-like protease in apoptotic cells
    • Emoto Y et al. Proteolytic activation of protein kinase C δ by an ICE-like protease in apoptotic cells. EMBO J 1995; 14: 6148-6156.
    • (1995) EMBO J , vol.14 , pp. 6148-6156
    • Emoto, Y.1
  • 45
    • 15844409177 scopus 로고    scopus 로고
    • D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis
    • Na SQ et al. D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis. J Biol Chem 1996; 271: 11209-11213.
    • (1996) J Biol Chem , vol.271 , pp. 11209-11213
    • Na, S.Q.1
  • 46
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Ann Rev Immunol 1994; 12: 991-1045.
    • (1994) Ann Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 47
    • 0028923130 scopus 로고
    • Novel packages of viral and self-antigens are generated during apoptosis
    • Rosen A, Casciola-Rosen LA, Ahearn J. Novel packages of viral and self-antigens are generated during apoptosis. J Exp Med 1995; 181: 1557-1561.
    • (1995) J Exp Med , vol.181 , pp. 1557-1561
    • Rosen, A.1    Casciola-Rosen, L.A.2    Ahearn, J.3
  • 48
    • 0027532285 scopus 로고
    • Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene
    • Levine B et al. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 1993; 361: 739-742.
    • (1993) Nature , vol.361 , pp. 739-742
    • Levine, B.1
  • 49
    • 0025289578 scopus 로고
    • Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen
    • McCauliffe DP et al. Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen. J Clin Invest 1990; 85: 1379-1391.
    • (1990) J Clin Invest , vol.85 , pp. 1379-1391
    • McCauliffe, D.P.1
  • 50
    • 0028606112 scopus 로고
    • Identification of calreticulin as a rubella virus RNA binding protein
    • Singh NK, Atreya CD, Nakhasi HL. Identification of calreticulin as a rubella virus RNA binding protein. Proc Natl Acad Sci USA 1994; 91: 12770-12774.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12770-12774
    • Singh, N.K.1    Atreya, C.D.2    Nakhasi, H.L.3
  • 51
    • 0025930801 scopus 로고
    • Specific binding of host cell proteins to the 3′-terminal stem-loop structure of rubella virus negative-strand RNA
    • Nakhasi HL, Cao X, Roualt TA, Liu T. Specific binding of host cell proteins to the 3′-terminal stem-loop structure of rubella virus negative-strand RNA. J Virol 1991; 65: 5961-5967.
    • (1991) J Virol , vol.65 , pp. 5961-5967
    • Nakhasi, H.L.1    Cao, X.2    Roualt, T.A.3    Liu, T.4
  • 52
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin BL. Systemic lupus erythematosus. Cell 1996; 85: 303-306.
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.L.1


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