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Volumn 103, Issue 6, 2004, Pages 2284-2290

Molecular response to imatinib in late chronic-phase chronic myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ALPHA INTERFERON; BCR ABL PROTEIN; BETA 2 MICROGLOBULIN; IMATINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 12144290269     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-07-2575     Document Type: Article
Times cited : (74)

References (39)
  • 1
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the ABL tyrosine kinase on the growth of BCR/ABL positive cells
    • Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the ABL tyrosine kinase on the growth of BCR/ABL positive cells. Nat Med. 1996;2:561-566.
    • (1996) Nat Med , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3
  • 2
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • Carroll M, Ohno-Jones S, Tamura S, et al. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood. 1997;90: 4947-4952.
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3
  • 3
    • 0033816156 scopus 로고    scopus 로고
    • The Abl protein-tyrosine kinase inhibitor, STI571, inhibits in vitro signal transduction mediated by c-Kit and PDGF receptors
    • Buchdunger E, Cioffi CL, Law N, et al. The Abl protein-tyrosine kinase inhibitor, STI571, inhibits in vitro signal transduction mediated by c-Kit and PDGF receptors. Pharmacol Exp Ther. 2000;295: 139-145.
    • (2000) Pharmacol Exp Ther , vol.295 , pp. 139-145
    • Buchdunger, E.1    Cioffi, C.L.2    Law, N.3
  • 4
    • 0034254249 scopus 로고    scopus 로고
    • Inhibition of c-kit receptor tyrosine kinase activity by STI571, a selective tyrosine kinase inhibitor
    • Heinrich MC, Griffith DJ, Druker BJ, et al. Inhibition of c-kit receptor tyrosine kinase activity by STI571, a selective tyrosine kinase inhibitor. Blood. 2000;96:925-932.
    • (2000) Blood , vol.96 , pp. 925-932
    • Heinrich, M.C.1    Griffith, D.J.2    Druker, B.J.3
  • 5
    • 0030853063 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells
    • Deininger MW, Goldman JM, Lyndon N, et al. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells. Blood. 1997;90:3691-3698.
    • (1997) Blood , vol.90 , pp. 3691-3698
    • Deininger, M.W.1    Goldman, J.M.2    Lyndon, N.3
  • 7
    • 0035122485 scopus 로고    scopus 로고
    • Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
    • Vigneri P, Wang JYJ. Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nat Med. 2001;7:228-234.
    • (2001) Nat Med , vol.7 , pp. 228-234
    • Vigneri, P.1    Wang, J.Y.J.2
  • 8
    • 0037093082 scopus 로고    scopus 로고
    • Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation
    • Holtz MS, Slovak ML, Zhang F, et al. Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation. Blood. 2002;99:3792-3800.
    • (2002) Blood , vol.99 , pp. 3792-3800
    • Holtz, M.S.1    Slovak, M.L.2    Zhang, F.3
  • 9
    • 0030031766 scopus 로고    scopus 로고
    • Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
    • Buchdunger E, Zimmermann J, Mett H, et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res. 1996;56:100-104.
    • (1996) Cancer Res , vol.56 , pp. 100-104
    • Buchdunger, E.1    Zimmermann, J.2    Mett, H.3
  • 10
    • 0033585504 scopus 로고    scopus 로고
    • In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor
    • le Coutre P, Mologni L, Cleris L, et al. In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor. J Natl Cancer Inst. 1999;91:163-168.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 163-168
    • Le Coutre, P.1    Mologni, L.2    Cleris, L.3
  • 11
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344:1031-1037.
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 12
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001; 344:1038-1042.
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 13
    • 0037186915 scopus 로고    scopus 로고
    • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    • Kantarjian HM, Sawyers CL, Hochhaus A, et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002;346:645-652.
    • (2002) N Engl J Med , vol.346 , pp. 645-652
    • Kantarjian, H.M.1    Sawyers, C.L.2    Hochhaus, A.3
  • 14
    • 0037085785 scopus 로고    scopus 로고
    • Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
    • Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood. 2002;99:1928-1937.
    • (2002) Blood , vol.99 , pp. 1928-1937
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3
  • 15
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood. 2002;99:3530-3538.
    • (2002) Blood , vol.99 , pp. 3530-3538
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 16
    • 0037092980 scopus 로고    scopus 로고
    • Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase
    • Kantarjian HM, Cortes J, O'Brien S, et al. Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase. Blood. 2002;99:3547-3553.
    • (2002) Blood , vol.99 , pp. 3547-3553
    • Kantarjian, H.M.1    Cortes, J.2    O'Brien, S.3
  • 17
    • 0037105560 scopus 로고    scopus 로고
    • A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias
    • Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood. 2002;100: 1965-1971.
    • (2002) Blood , vol.100 , pp. 1965-1971
    • Ottmann, O.G.1    Druker, B.J.2    Sawyers, C.L.3
  • 18
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348:994-1004.
    • (2003) N Engl J Med , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 19
    • 10744231480 scopus 로고    scopus 로고
    • Result of high-dose imatinib mesylate in patients with Philadelphia chromosome-positive chronic myeloid leukemia after failure of interferon-α
    • Cortes J, Giles F, O'Brien S, et al. Result of high-dose imatinib mesylate in patients with Philadelphia chromosome-positive chronic myeloid leukemia after failure of interferon-α. Blood. 2003;102: 83-86.
    • (2003) Blood , vol.102 , pp. 83-86
    • Cortes, J.1    Giles, F.2    O'Brien, S.3
  • 20
    • 0027207407 scopus 로고
    • Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: Correlations with acute graft-versus-host disease and relapse
    • Cross NCP, Hughes TP, Feng L, et al. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft-versus-host disease and relapse. Br J Haematol. 1993;84:67-74.
    • (1993) Br J Haematol , vol.84 , pp. 67-74
    • Cross, N.C.P.1    Hughes, T.P.2    Feng, L.3
  • 21
    • 0030873760 scopus 로고    scopus 로고
    • Detection of BCR/ABL RNA transcripts using the polymerase chain reaction is highly predictive for relapse in patients transplanted with unrelated marrow grafts for chronic myelogenous leukaemia
    • Drobyski WR, Endean DJ, Klein JP, Hessner MJ. Detection of BCR/ABL RNA transcripts using the polymerase chain reaction is highly predictive for relapse in patients transplanted with unrelated marrow grafts for chronic myelogenous leukaemia. Br J Haematol. 1997;98:458-466.
    • (1997) Br J Haematol , vol.98 , pp. 458-466
    • Drobyski, W.R.1    Endean, D.J.2    Klein, J.P.3    Hessner, M.J.4
  • 22
    • 0033135248 scopus 로고    scopus 로고
    • Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making?
    • Federl SF, Talpaz M, Kantarjian HM, et al. Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making? Blood. 1999;93:2755-2759.
    • (1999) Blood , vol.93 , pp. 2755-2759
    • Federl, S.F.1    Talpaz, M.2    Kantarjian, H.M.3
  • 23
    • 0034650993 scopus 로고    scopus 로고
    • Persistence of BCR-ABL genomic rearrangement in chronic myeloid leukemia patients in complete and sustained cytogenetic remission after interferon-α therapy or allogeneic bone marrow transplantation
    • Chomel JC, Brizard F, Veinstein A, et al. Persistence of BCR-ABL genomic rearrangement in chronic myeloid leukemia patients in complete and sustained cytogenetic remission after interferon-α therapy or allogeneic bone marrow transplantation. Blood. 2000;95:404-409.
    • (2000) Blood , vol.95 , pp. 404-409
    • Chomel, J.C.1    Brizard, F.2    Veinstein, A.3
  • 24
    • 0035885940 scopus 로고    scopus 로고
    • The significance of bcr-abl molecular detection in chronic myeloid leukemia patients "late," 18 months or more after transplantation
    • Radich JP, Gooley T, Bryant E, et al. The significance of bcr-abl molecular detection in chronic myeloid leukemia patients "late," 18 months or more after transplantation. Blood. 2001;98:1701-1707.
    • (2001) Blood , vol.98 , pp. 1701-1707
    • Radich, J.P.1    Gooley, T.2    Bryant, E.3
  • 26
    • 0032757710 scopus 로고    scopus 로고
    • Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia
    • Van Dongen JJ, Gabert JA, Delabesse E, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia. 1999;13:1901-1928.
    • (1999) Leukemia , vol.13 , pp. 1901-1928
    • Van Dongen, J.J.1    Gabert, J.A.2    Delabesse, E.3
  • 27
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of "real-time" quantitative reverse transcriptase polymerase chain reaction (RQ-PCR) of fusion gene transcripts for residual disease detection in leukemia: A Europe Against Cancer Program
    • Gabert J, Van Der Velden VH, Bi W, et al. Standardization and quality control studies of "real-time" quantitative reverse transcriptase polymerase chain reaction (RQ-PCR) of fusion gene transcripts for residual disease detection in leukemia: a Europe Against Cancer Program. Leukemia. 2003;17:2318-2357.
    • (2003) Leukemia , vol.17 , pp. 2318-2357
    • Gabert, J.1    Van Der Velden, V.H.2    Bi, W.3
  • 28
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation in each patient; II, analysis and examples
    • Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation in each patient; II, analysis and examples. Br J Cancer. 1977;35:1-39.
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3
  • 29
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 30
    • 20844461361 scopus 로고    scopus 로고
    • Risk and early cytogenetic response to imatinib and interferon in chronic myeloid leukemia
    • Rosti G, Trabacchi E, Bassi S, et al. Risk and early cytogenetic response to imatinib and interferon in chronic myeloid leukemia. Hematologica. 2003;88:256-259.
    • (2003) Hematologica , vol.88 , pp. 256-259
    • Rosti, G.1    Trabacchi, E.2    Bassi, S.3
  • 31
    • 0031440310 scopus 로고    scopus 로고
    • New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia
    • Carella AM, Frassoni F, Melo J, et al. New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia. Haematologica. 1997;82:478-495.
    • (1997) Haematologica , vol.82 , pp. 478-495
    • Carella, A.M.1    Frassoni, F.2    Melo, J.3
  • 32
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999;340:1330-1340.
    • (1999) N Engl J Med , vol.340 , pp. 1330-1340
    • Sawyers, C.L.1
  • 33
    • 18744419356 scopus 로고    scopus 로고
    • Molecular heterogeneity in complete cytogenetic responders after interferon-a therapy for chronic myelogenous leukemia: Low levels of minimal residual disease are associated with continuing remission
    • Hochhaus A, Reiter A, Saubele S, et al. Molecular heterogeneity in complete cytogenetic responders after interferon-a therapy for chronic myelogenous leukemia: low levels of minimal residual disease are associated with continuing remission. Blood. 2000;95:62-66.
    • (2000) Blood , vol.95 , pp. 62-66
    • Hochhaus, A.1    Reiter, A.2    Saubele, S.3
  • 34
    • 0034126172 scopus 로고    scopus 로고
    • Quantification of BCR-ABL transcripts in CML patients in cytogenetic remission after interferon-alpha-based therapy
    • Martinelli G, Testoni N, Amabile M, et al. Quantification of BCR-ABL transcripts in CML patients in cytogenetic remission after interferon-alpha-based therapy. Bone Marrow Transplant. 2000; 25:729-736.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 729-736
    • Martinelli, G.1    Testoni, N.2    Amabile, M.3
  • 35
    • 0037255789 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for chronic myeloid leukemia
    • Barret J. Allogeneic stem cell transplantation for chronic myeloid leukemia. Semin Hematol. 2003; 40:59-71.
    • (2003) Semin Hematol , vol.40 , pp. 59-71
    • Barret, J.1
  • 36
    • 26744448589 scopus 로고    scopus 로고
    • Dynamics of BCR-ABL mRNA transcript expression in newly diagnosed CML patients treated with imatinib or interferon alpha
    • Mueller MC, Gattermann N, Lahaye T, et al. Dynamics of BCR-ABL mRNA transcript expression in newly diagnosed CML patients treated with imatinib or interferon alpha [abstract]. Blood. 2002;100:1413a.
    • (2002) Blood , vol.100
    • Mueller, M.C.1    Gattermann, N.2    Lahaye, T.3
  • 37
    • 0037568145 scopus 로고    scopus 로고
    • Molecular responses to imatinib (STI571) or interferon + Ara-C as initial therapy for CML: Results in the IRIS study
    • Hughes T, Kaeda J, Brandford S, et al. Molecular responses to imatinib (STI571) or interferon + Ara-C as initial therapy for CML: results in the IRIS study [abstract]. Blood. 2002;100:345a.
    • (2002) Blood , vol.100
    • Hughes, T.1    Kaeda, J.2    Brandford, S.3
  • 38
    • 0037315281 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias
    • Gambacorti-Passerini CB, Gunby RH, Piazza R, et al. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet. 2003;4:75-85.
    • (2003) Lancet , vol.4 , pp. 75-85
    • Gambacorti-Passerini, C.B.1    Gunby, R.H.2    Piazza, R.3
  • 39
    • 0037260861 scopus 로고    scopus 로고
    • Management decisions in chronic myeloid leukemia
    • Goldman JM, Marin D. Management decisions in chronic myeloid leukemia. Semin Hematol. 2003; 40:97-103.
    • (2003) Semin Hematol , vol.40 , pp. 97-103
    • Goldman, J.M.1    Marin, D.2


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