Combined effects of AT1 and ETA receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats

General Pharmacology: The Vascular System

Volumn 34, Issue 5, 2000, Pages 337-342

  Pollock, David M ^a   Derebail, Vimal K ^a   Yamamoto, Tatsuo ^a   Pollock, Jennifer S ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Deoxycorticosterone; Endothelin 1; Hypertension; Kidney

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ATRASENTAN; CANDESARTAN HEXETIL; DEOXYCORTICOSTERONE ACETATE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; FIBRONECTIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG ANTAGONISM; DRUG EFFECT; DRUG PELLET; GLOMERULUS FILTRATION RATE; HEMODYNAMICS; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY MEDULLA; MALE; MALIGNANT HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; RECEPTOR BLOCKING; SODIUM EXCRETION; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; URINE VOLUME;

ANGIOTENSIN II; ANIMALS; BENZIMIDAZOLES; BLOOD PRESSURE; BODY WEIGHT; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ENDOTHELIN-1; HYPERTENSION; KIDNEY; MALE; NATRIURESIS; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; RECEPTORS, ENDOTHELIN; TETRAZOLES;

EID: 0034442454     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(00)00079-3     Document Type: Article

References (20)

1. A receptor blockade attenuates the hypertension but not renal dysfunction in DOCA-salt rats. Am. J. Physiol. Regul., Integr. Comp. Physiol. 275, R245-R252.
2. Benigni, A., Remuzzi, G., 1998. Mechanism of progression of renal disease: growth factors and related mechanisms. J. Hypertens. 16, S9-S12.
3. Border, W.A., Noble, N.A., 1994. Transforming growth factor β in tissue fibrosis. N. Engl. J. Med. 311, 1286-1292.
4. Border, W. A., Noble, N. A., 1998. Interactions of transforming growth factor-beta and angiotensin II in renal fibrosis. Hypertension 31, 181-188.
5. d'Uscio, L.V., Moreau, P., Shaw, S., Takase, H., Barton, M., Lüscher, T.F., 1997. Effects of chronic ETA-receptor blockade in angiotensin II-induced hypertension. Hypertension 29, 435-441.
6. Gomez-Garre, D., Ruiz-Ortega, M., Ortego, M., Largo, R., Lopez-Armada, J.J., Plaza, J.J., Gonzalez, E., Egido, J., 1996. Effects and interactions of endothelin-l and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension 27, 885-892.
7. Herizi, A., Jover, B., Bouriquet, N., Mimran, A., 1998. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade. Hypertension 31, 10-14.
8. Hutchinson, I.V., 1998. An endothelin-transforming growth factor beta pathway in the nephrotoxicity of immunosuppressive drugs. Curr. Opin. Nephrol. Hypertens. 7, 665-671.
9. Kirn, S., Ohta, K., Hamaguchi, A., Omura, T., Yukimura, T., Miura, K., Inada, Y., Wada, T., Ishimura, Y, Chatani, F., Iwao, H., 1994. Role of angiotensin II in renal injury of deoxycorticosterone acetate-salt hypertensive rats. Hypertension 24, 195-204.
10. Laragh, J.H., 1995. Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke). J. Hum. Hypertens. 9, 385-390.
11. Levy, B.I., 1998. The potential role of angiotensin II in the vasculature. J. Hum. Hypertens. 12, 283-287.
12. Morimoto, S., Ogihara, T., 1994. TCV-116: a new angiotensin II type-I receptor antagonist. Cardiovasc. Drug Rev. 12, 153-164.
13. Nicholls, M.G., Richards, A.M., Aganval, M., 1998. The importance of the renin-angiotensin system in cardiovascular disease. J. Hum. Hypertens. 12, 295-299.
14. A-selective receptor antagonist. J. Pharmacol. Exp. Ther. 276, 473-481.
15. Pollock, D.M., 2000. Renal endothelin in hypertension. Curr. Opin. Nephrol. Hypertens. 9, 157-164.
16. Pollock, D.M., Allcock, G.H., Pollock, J.S., 2000. Upregulation of endothelin B receptors in kidneys of DOCA-salt hypertensive rats. Am. J. Physiol: Renal Physiol. 278, F279-F286.
17. Ponicke, K., Heinroth-Hoffman, I., Becker, K., Brodde, O.E., 1997. Trophic effect of angiotensin II in neonatal rat cardiomyocytes: role of endothelin-1 and non-myocyte cells. Br. J. Pharmacol. 121,118 -124.
18. Rajagopalan, S., Laursen, J.B., Borthayre, A., Kurz, S., Keiser, J., Haleen, A., Giaid, A., Harrison, D.G., 1997. Role for endothelin-1 in angiotensin H-mediated hypertension. Hypertension 30, 29-34.
19. Wada, T., Kanagawa, R., Ishimura, Y., Inada, Y., Nishikawa, K., 1995. Role of angiotensin II in cerebrovascular and renal damage in deoxycorticosterone acetate-salt hypertensive rats. J. Hypertens. 13, 113-122.
20. Yamamoto, T., Watanabe, R., Ikegaya, N., Fujigaki, Y., Matsui, K., Masaoka, H., Nagase, M., Hishida, A., 1998. Expression of Types I, II and III TGF- receptors in human glomerulonephritis. J. Am. Soc. Nephrol. 9, 2253-2261.