Large pore formation uniquely associated with P2X7 purinergic receptor channels. Focus on "Are second messengers crucial for opening the pore associated with P2X7 receptor?"

American Journal of Physiology - Cell Physiology

Volumn 288, Issue 2 57-2, 2005, Pages

  Liang, Lihua ^a   Schwiebert, Erik M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CASPASE; CATION CHANNEL; CELL PROTEIN; CYSTEINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PURINE P2X7 RECEPTOR; PURINE P2Y RECEPTOR;

ALPHA HELIX; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; EDITORIAL; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

EID: 12144277501     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00532.2004     Document Type: Editorial

References (16)

1. Abbracchio MP and Burnstock G. Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol Ther 64: 445-475, 1994.
2. 2+ influx. Biochem J 374: 51-61, 2003.
3. Benos DJ and Stanton BA. Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. J Physiol 520: 631-644, 1999.
4. 7R)-induced pore formation in human THP-1 cells. J Pharmacol Exp Ther 308: 1053-1061, 2004.
5. 7 receptor? Am J Physiol Cell Physiol 288: C194-C205, 2005.
6. 6 receptors by N-linked glycosylation: identification of a novel αβ-methylene ATP-sensitive phenotype. Mol Pharmacol 65: 979-985, 2004.
7. 7-transfected H-EK293 cells. Mol Biol Cell 14: 2655-2664, 2003.
8. North RA. Molecular physiology of P2X receptors. Physiol Rev 82: 1013-1067, 2002.
9. Schwiebert EM and Zsembery A. Extracellular ATP as a signaling molecule for epithelial cells. Biochim Biophys Acta 1615: 7-32, 2003.
10. 7 purinergic receptor stimulation activate a common cytolytic pore. Am J Physiol Cell Physiol 277: C766-C776, 1999.
11. 7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. J Blol Chem 278: 8853-8860, 2003.
12. 7-induced pore formation and cell death in pericyte-containing retinal microvessels. Am J Physiol Cell Physiol (In Press). doi:10.1152/ajpcell.00380.2004.
13. 7). Science 272: 735-738, 1996.
14. 7 receptor C terminus. J Biol Chem 277: 34017-34023, 2002.
15. Zsembery A, Boyce AT, Liang L, Peti-Peterdi J, Bell PD, and Schwiebert EM. Sustained calcium entry through P2X nucleotide receptor channels in human airway epithelial cells. J Biol Chem 278: 13398-13408, 2003.
16. Zsembery A, Fortenberry JA, Liang L, Bebok Z, Tucker TA, Boyce AT, Braunstein GM, Welty E, Bell PD, Sorscher EJ, Clancy JP, and Schwiebert EM. Extracellular zinc and ATP restore chloride secretion across cystic fibrosis airway epithelia by triggering calcium entry. J Biol Chem 279: 10720-10729, 2004.