NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain

Biochemistry

Volumn 44, Issue 2, 2005, Pages 694-703

  Finerty Jr , Patrick J ^a,b   Mittermaier, Anthony K ^a,b   Muhandiram, Ranjith ^b   Kay, Lewis E ^b,c   Forman Kay, Julie D ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOCHEMISTRY; NUCLEAR MAGNETIC RESONANCE; PROTEINS;

BINDING SITES; MOBILITY; NANOSECONDS; PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR);

POLYPEPTIDES;

PHOSPHOLIPASE C GAMMA; PHOSPHOLIPASE C GAMMA1; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; ENZYME SUBUNIT; LIGAND BINDING; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE;

AMIDES; CARBON ISOTOPES; DEUTERIUM; LIGANDS; NANOTECHNOLOGY; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOTYROSINE; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; PROTEIN CONFORMATION; SRC HOMOLOGY DOMAINS; THERMODYNAMICS; TIME FACTORS;

EID: 12144259853     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048641k     Document Type: Article

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