Prion protein with Y145STOP mutation induces mitochondria-mediated apoptosis and PrP-containing deposits in vitro

Biochemical and Biophysical Research Communications

Volumn 327, Issue 3, 2005, Pages 894-899

  Hachiya, Naomi S ^a,b   Watanabe, Kota ^a,b   Kawabata, Makiko Y ^a,b   Jozuka, Akiko ^a,b   Kozuka, Yoshimichi ^a   Sakasegawa, Yuji ^a   Kaneko, Kiyotoshi ^a,b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cellular prion protein; Green fluorescent protein; Mitochondria mediated apoptosis; PrP Y145STOP mutation; PrP containing deposits

Indexed keywords

CYTOCHROME C; DNA FRAGMENT; GREEN FLUORESCENT PROTEIN; PORIN; PRION PROTEIN; PROTEASOME;

AMBER MUTANT; ANIMAL CELL; APOPTOSIS; ARTICLE; CODON; CYTOSOL; ELECTRON; ENZYME INHIBITION; GENE MUTATION; GENETIC TRANSFECTION; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; HIPPOCAMPUS; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD LABELING; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SECRETION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CODON; CYTOCHROMES C; CYTOSOL; DNA; GERSTMANN-STRAUSSLER-SCHEINKER DISEASE; LYSOSOMES; MICE; MITOCHONDRIA; MUTATION; NEUROBLASTOMA; NEURONS; NEUROPROTECTIVE AGENTS; PRIONS;

EID: 11844304398     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.12.079     Document Type: Article

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