A novel method to calculate the extent and amount of drug transported into CSF after intranasal administration

International Journal of Pharmaceutics

Volumn 289, Issue 1-2, 2005, Pages 159-166

  Shi, Zhenqi ^a   Zhang, Qizhi ^a   Jiang, Xinguo ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Brain targeting; Cerebrospinal fluid; Clearance; Extent; Intranasal administration; Meptazinol hydrochloride

Indexed keywords

MEPTAZINOL;

AB INITIO CALCULATION; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; CISTERNA MAGNA; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG TRANSPORT; MALE; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; BIOLOGICAL AVAILABILITY; CARBON RADIOISOTOPES; CISTERNA MAGNA; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; MALE; MEPTAZINOL; OLFACTORY PATHWAYS; RATS; RATS, SPRAGUE-DAWLEY; SUCROSE; TISSUE DISTRIBUTION;

EID: 11844283921     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.11.006     Document Type: Article

References (23)

1. H.H. Chow, N. Anavy, and A. Villalobos Direct nose-brain transport of benzoylecgonine following intranasal administration in rats J. Pharm. Sci. 90 2001 1729 1735
2. K.J. Chou, and M.D. Donovan The distribution of local anaesthetics into the CSF following intranasal administration Int. J. Pharm. 168 1998 137 145
3. H. Cserr Potassium exchange between cerebrospinal fluid, plasma, and brain Am. J. Physiol. 209 1965 1219 1226
4. M. Dahlin, and E. Bjork Nasal absorption of (S)-UH-301 and its transport into the cerebrospinal fluid of rats Int. J. Pharm. 195 2000 197 205
5. M. Dahlin, and E. Bjork Nasal administration of a physostigmine analogue (NXX-066) for Alzheimer's disease to rats Int. J. Pharm. 212 2001 264 274
6. N. Einer-Jensen, and L. Larsen Local transfer of diazepam, but not of cocaine, from the nasal cavities to the brain arterial blood in rats Pharmacol. Toxicol. 87 2000 276 278
7. N. Einer-Jensen, and L. Larsen Transfer of tritiated water, tyrosine, and propanol from the nasal cavity to cranial arterial blood in rats Exp. Brain. Res. 130 2000 200 216
8. S.S. Erlich, J.G. McComb, S. Hyman, and M.H. Weiss Ultrastructural morphology of the olfactory pathway for cerebrospinal fluid drainage in the rabbit J. Neurosurg. 64 1986 466 473
9. R.A. Franklin The clinical pharmacokinetics and metabolism of the analgesic meptazinol Xenobiotica 18 1988 105 112
10. B.E. Hirsch, M. Amodio, A.I. Einzig, R. Halevy, and R. Soeiro Instillation of vancomycin into a cerebrospinal fluid reservoir to clear infection: pharmacokinetic considerations J. Infect. Dis. 163 1991 197 200
11. B. Holmes, and A. Ward Meptazinol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy Drugs 30 1985 285 312
12. L. Illum Transport of drugs from the nasal cavity to the central nervous system Eur. J. Pharm. Sci. 11 2000 1 18
13. L. Illum Nasal drug delivery - possibilities, problems and solutions J. Control Release 87 2003 187 198
14. J. Kawakami, K. Yamamoto, Y. Sawasa, and T. Iga Prediction of brain delivery of ofloxacin, a new quinolone, in the human from animal data J. Pharmacokinet. Biopharm. 22 1994 207 227
15. J. Kreuter, R.N. Alyautdin, D.A. Kharkevich, and A.A. Ivanov Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles) Brain Res. 674 1995 171 174
16. X.F. Liu, J.R. Fawcett, R.G. Thorne, and W.H. Frey II Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion Neurosci. Lett. 308 2001 91 94
17. K. Muraszko, C. Sung, S. Walbridge, L. Greenfield, R.L. Dedrick, E.H. Oldfield, and R.J. Youle Pharmacokinetics and toxicology of immnuotoxins administered into the subarachnoid space in nonhuman primates and rodents Cancer Res. 53 1993 3752 3757
18. R. Payne, T.L. Gradert, and C.E. Inturrisi Cerebrospinal fluid distribution of opioids after intraventricular and lumbar subarachnoid administration in sheep Life Sci. 59 1996 1307 1321
19. W.M. Pardridge Vector-mediated drug delivery to the brain Adv. Drug Deliv. Rev. 36 1999 299 321
20. T. Sakane, S. Yamashita, N. Yata, and H. Sezaki Transnasal delivery of 5-fluorouracil to the brain in the rat J. Drug Target 7 1999 233 240
21. M.P. Van den Berg, S.G. Romeijn, J.C. Verhoef, and F.W. Merkus Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity J. Neurosci. Methods 116 2002 99 107
22. Y. Wang, R. Aun, and F.L. Tse Brain uptake of dihydroergotamine after intravenous and nasal administration in the rat Biopharm. Drug Dispos. 19 1998 571 575
23. F. Wang, X. Jiang, and W. Lu Profiles of methotrexate in blood and CSF following intranasal and intravenous administration to rats Int. J. Pharm. 263 2003 1 7