Antisense recognition of the HER-2 mRNA: Effects of phosphorothioate substitution and polyamines on DNA·RNA, RNA·RNA, and DNA·DNA duplex stability

Biochemistry

Volumn 44, Issue 1, 2005, Pages 303-312

  Venkiteswaran, Sripriya ^a,b   Vijayanathan, Veena ^a   Shirahata, Akira ^e   Thomas, Thresia ^a,c,d   Thomas, T J ^a,b,f  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^d RUTGERS UNIVERSITY   (United States)

^e JOSAI UNIVERSITY   (Japan)

^f Division of Internal Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOLOGICAL ORGANS; DNA; GENES; POSITIVE IONS; SPECTRUM ANALYSIS; TUMORS;

DUPLEXES; OLIGONUCLEOTIDES; POLYAMINES; SUBSETS;

RNA;

ANTISENSE OLIGODEOXYNUCLEOTIDE; AZAMETHONIUM; COMPLEMENTARY DNA; COMPLEMENTARY RNA; DOUBLE STRANDED DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; METHENAMINE; OLIGONUCLEOTIDE; PHOSPHODIESTERASE; PHOSPHOROTHIOIC ACID; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE;

ARTICLE; CIRCULAR DICHROISM; CODON; CONFORMATION; DNA HELIX; DNA RNA HYBRIDIZATION; GENE EXPRESSION; GENETIC STABILITY; MELTING POINT; MOLECULAR RECOGNITION; PRIORITY JOURNAL; RNA RNA HYBRIDIZATION; STRUCTURE ANALYSIS; THERMOSTABILITY;

BASE SEQUENCE; CIRCULAR DICHROISM; DNA; DRUG STABILITY; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHATES; POLYAMINES; RECEPTOR, ERBB-2; RNA; RNA, MESSENGER; THERMODYNAMICS;

EID: 11844280279     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0485272     Document Type: Article

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