Downregulation of NF-κB activity associated with alteration in proliferative response in the spleen after burn injury

Shock

Volumn 23, Issue 1, 2005, Pages 73-79

  Phan, Ho H ^b   Cho, Kiho ^b   Nelson, Heather A ^b   Shin, Soowan ^b   Jeong, Jayoung ^b   Greenhalgh, David G ^a  

^a SHRINERS HOSPITALS FOR CHILDREN NORTHERN CALIFORNIA   (United States)

^b NONE

Author keywords

B cells; I B ; Immune; PCNA; rel A (p65); T cells; Thermal

Indexed keywords

CYCLINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; IMMUNITY; IMMUNOCOMPETENT CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPLEEN CELL; WESTERN BLOTTING; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; CELL NUCLEUS; CYTOLOGY; CYTOPLASM; DENSITOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PHENOTYPE; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; T LYMPHOCYTE; TIME;

ANIMALS; B-LYMPHOCYTES; BLOTTING, WESTERN; BURNS; CELL NUCLEUS; CELL PROLIFERATION; CYTOPLASM; DENSITOMETRY; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; MICE; NF-KAPPA B; PHENOTYPE; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; T-LYMPHOCYTES; TIME FACTORS;

EID: 11444261016     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000148052.66645.67     Document Type: Article

References (27)

1. O'Riordain MG, Collins KH, Pilz M, Saporoschetz IB, Mannick JA, Rodrick ML: Modulation of macrophage hyperactivity improves survival in a burn-sepsis model. Arch Surg 127:152-157, 1992.
2. Schwacha MG, Schneider CP, Chaudry IH: Differential expression and tissue compartmentalization of the inflammatory response following thermal injury. Cytokine 17:266-274, 2002.
3. Biffl WL, Moore EE, Moore FA, Peterson VM: Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation? Ann Surg 224:647-664, 1996.
4. Nishimura T, Yamamoto H, deSerres S, Meyer AA: Transforming growth factor-β impairs postburn immunoglobulin production by limiting B-cell proliferation, but not cellular synthesis. J Trauma 46:881-885, 1999.
5. Teodorczyk-Injeyan JA, Sparkes BG, Mills GB, Peters WJ, Falk RE: Impairment of T cell activation in burn patients: a possible mechanism of thermal injury-induced immunosuppression. Clin Exp Immunol 65:570-581, 1986.
6. + signaling and proliferative responses during sepsis. Shock 1:267-272, 1994.
7. Markley K, Smallman ET: Effect of thermal trauma on numbers and function of T and B cells from mouse spleen. Int Arch Allergy Appl Immunol 54:238-246, 1977.
8. Organ BC, Antonacci AC, Chiao J, Kumar A, de Riesthal HF, Yuan L, Black D, Calvano SE: Changes in lymphocyte number and phenotype in seven lymphoid compartments after thermal injury. Ann Surg 210:78-89, 1989.
9. Caamano J, Hunter CA: NF-κB family of transcription factors: central regulators of innate and adaptive immune functions. Clin Microbiol Rev 15:414-429, 2002.
10. Barnes PJ, Karin M: Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071, 1997.
11. Samy TS, Ayala A, Catania RA, Chaudry IH: Trauma-hemorrhage activates signal transduction pathways in mouse splenic T cells. Shock 9:443-450, 1998.
12. O'Suilleabhain CB, Kim S, Rodrick MR, Mannick JA, Lederer JA: Injury induces alterations in T-cell NF-κB and AP-1 activation. Shock 15:432-437, 2001.
13. Maass DL, Hybki DP, White J, Horton JW: The time course of cardiac NF-κB activation and TNF-α secretion by cardiac myocytes after burn injury: contribution to burn-related cardiac contractile dysfunction. Shock 17:293-299, 2002.
14. Zingarelli B, Sheehan M, Wong HR: Nuclear factor-κB as a therapeutic target in critical care medicine. Crit Care Med 31:S105-S111, 2003.
15. Ito CY, Kazantsev AG, Baldwin AS Jr: Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNF-α. Nucleic Acids Res 22:3787-3792, 1994.
16. Krappmann D, Scheidereit C: Regulation of NF-κB activity by IκBα and IκBβ stability. Immunobiology 198:3-13, 1997.
17. Arenzana-Seisdedos F, Thompson J, Rodriguez MS, Bachelerie F, Thomas D, Hay RT: Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB. Mol Cell Biol 15:2689-2696, 1995.
18. Cho K, Adamson LK, Park J, Greenhalgh DG: Burn injury-mediated alterations in cell cycle progression in lymphoid organs of mice. Shock 19:138-143, 2003.
19. Stieritz DD, Holder IA: Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa. J Infect Dis 131:688-691, 1975.
20. Schreiber E, Matthias P, Muller MM, Schaffner W: Rapid detection of octamer binding proteins with "mini-extracts" prepared from a small number of cells. Nucleic Acids Res 17:6419, 1989.
21. Maga G, Hubscher U: Proliferating cell nuclear antigen (PCNA): a dancer with many partners. J Cell Sci 116:3051-3060, 2003.
22. Miyachi K, Fritzler MJ, Tan EM: Autoantibody to a nuclear antigen in proliferating cells. J Immunol 121:2228-2234, 1978.
23. Yamamoto H, Siltharm S, deSerres S, Hultman CS, Meyer AA: Immediate burn wound excision restores antibody synthesis to bacterial antigen. J Surg Res 63:157-162, 1996.
24. Chen F, Castranova V, Shi X: New insights into the role of nuclear factor-κB in cell growth regulation. Am J Pathol 159:387-397, 2001.
25. Rosenfeld ME, Prichard L, Shiojiri N, Fausto N: Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol 156:997-1007, 2000.
26. Gamelli RL, Hebert JC, Foster RS Jr: Effect of burn injury on granulocyte and macrophage production. J Trauma 25:615-619, 1985.
27. Schwacha MG: Macrophages and post-burn immune dysfunction. Burns 29:1-14, 2003.