Temperature effects on the catalytic activity of the D38E mutant of 3-Oxo-Δ5-steroid isomerase: Favorable enthalpies and entropies of activation relative to the nonenzymatic reaction catalyzed by acetate ion

Journal of the American Chemical Society

Volumn 126, Issue 50, 2004, Pages 16416-16425

  Houck, Wendy J ^a   Pollack, Ralph M ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; CATALYSIS; CATALYST ACTIVITY; ENTHALPY; ENTROPY; ISOMERIZATION;

ACETATE IONS; ARRHENIUS PLOT; CHEMICAL TRANSITION STATES; ENTHALPIC STABILIZATION;

ENZYMES;

ACETIC ACID; ANDROSTENEDIOL DERIVATIVE; ANDROSTENEDIONE; ENOLASE; MUTANT PROTEIN; STEROID DELTA ISOMERASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENTHALPY; ENTROPY; EVALUATION; INTERMETHOD COMPARISON; ISOMERIZATION; LINEAR SYSTEM; NONHUMAN; PARAMETER; REACTION ANALYSIS; REDUCTION; STATISTICAL MODEL; TEMPERATURE;

CATALYSIS; ENZYME ACTIVATION; KINETICS; MUTAGENESIS, SITE-DIRECTED; STEROID ISOMERASES; TEMPERATURE; THERMODYNAMICS;

EID: 11444252914     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja046819k     Document Type: Article

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